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3LVX
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BU of 3lvx by Molmil
Crystal structure of human alpha-defensin 1 (I6A mutant)
分子名称: GLYCEROL, Neutrophil defensin 1, SULFATE ION
著者Pazgier, M, Lu, W.
登録日2010-02-22
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
4EYC
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BU of 4eyc by Molmil
Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD)
分子名称: Cathelicidin antimicrobial peptide
著者Pazgier, M, Pozharski, E, Toth, E, Lu, W.
登録日2012-05-01
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37.
Biochemistry, 52, 2013
3LO1
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BU of 3lo1 by Molmil
Crystal structure of human alpha-defensin 1 (Y16A mutant)
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, AZIDE ION, Neutrophil defensin 1
著者Pazgier, M, Lu, W.
登録日2010-02-03
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LNZ
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BU of 3lnz by Molmil
Crystal structure of human MDM2 with a 12-mer peptide inhibitor PMI (N8A mutant)
分子名称: 12-mer peptide inhibitor, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2
著者Pazgier, M, Lu, W.
登録日2010-02-03
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.
J.Mol.Biol., 398, 2010
3LOE
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BU of 3loe by Molmil
Crystal structure of human alpha-defensin 1 (F28A mutant)
分子名称: GLYCEROL, Neutrophil defensin 1, SULFATE ION
著者Pazgier, M, Lu, W.
登録日2010-02-03
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LNJ
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BU of 3lnj by Molmil
Crystal structure of human MDM2 in complex with D-peptide inhibitor (DPMI-alpha)
分子名称: CHLORIDE ION, D-peptide inhibitor, E3 ubiquitin-protein ligase Mdm2, ...
著者Pazgier, M, Lu, W.
登録日2010-02-02
公開日2010-03-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A left-handed solution to peptide inhibition of the p53-MDM2 interaction.
Angew.Chem.Int.Ed.Engl., 49, 2010
3LO4
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BU of 3lo4 by Molmil
Crystal structure of human alpha-defensin 1 (R24A mutant)
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Neutrophil defensin 1
著者Pazgier, M, Lu, W.
登録日2010-02-03
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
4LB7
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BU of 4lb7 by Molmil
Crystal structure of human alpha-defensin 1 (HNP1) Y16A/I20A/L25A/F28A mutant.
分子名称: Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
4LB1
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BU of 4lb1 by Molmil
Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant
分子名称: Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
4LBB
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BU of 4lbb by Molmil
Crystal structure of human alpha-defensin 1 (HNP1) I20A mutant
分子名称: CHLORIDE ION, Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.719 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
4LBF
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BU of 4lbf by Molmil
Crystal structure of HUMAN ALPHA-DEFENSIN 1 (HNP1) I20A/L25A mutant
分子名称: GLYCEROL, Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
5VK0
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BU of 5vk0 by Molmil
Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
5VK1
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BU of 5vk1 by Molmil
Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
3TPX
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BU of 3tpx by Molmil
Crystal structure of human MDM2 in complex with a trifluoromethylated D-peptide inhibitor
分子名称: ACETATE ION, CHLORIDE ION, D-peptide inhibitor DPMI-delta, ...
著者Wu, X, Pazgier, M.
登録日2011-09-08
公開日2012-06-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An Ultrahigh Affinity d-Peptide Antagonist Of MDM2.
J.Med.Chem., 55, 2012
4RE8
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BU of 4re8 by Molmil
Crystal Structure of TR3 LBD in complex with Molecule 5
分子名称: 1-(3,4,5-trihydroxyphenyl)dodecan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Weijia, W, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W.
登録日2014-09-22
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity
Chem.Biol., 22, 2015
5TXF
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BU of 5txf by Molmil
Crystal structure of Lecithin:cholesterol acyltransferase (LCAT) in a closed conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phosphatidylcholine-sterol acyltransferase, ...
著者Manthei, K.A, Glukhova, A, Tesmer, J.J.G.
登録日2016-11-16
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I.
J. Biol. Chem., 292, 2017
5XME
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BU of 5xme by Molmil
Solution structure of C-terminal domain of TRADD
分子名称: Tumor necrosis factor receptor type 1-associated DEATH domain protein
著者Lin, Z, Zhang, N.
登録日2017-05-15
公開日2017-09-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily.
Sci Rep, 7, 2017
1POB
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BU of 1pob by Molmil
CRYSTAL STRUCTURE OF COBRA-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE
分子名称: 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2
著者White, S.P, Scott, D.L, Otwinowski, Z, Sigler, P.B.
登録日1992-09-07
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue.
Science, 250, 1990
1POC
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BU of 1poc by Molmil
CRYSTAL STRUCTURE OF BEE-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE
分子名称: 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2
著者Scott, D.L, Otwinowski, Z, Sigler, P.B.
登録日1992-09-07
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.
Science, 250, 1990
1POE
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BU of 1poe by Molmil
STRUCTURES OF FREE AND INHIBITED HUMAN SECRETORY PHOSPHOLIPASE A2 FROM INFLAMMATORY EXUDATE
分子名称: 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2
著者Scott, D.L, White, S.P, Sigler, P.B.
登録日1992-09-07
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of free and inhibited human secretory phospholipase A2 from inflammatory exudate.
Science, 254, 1991
8JQ9
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BU of 8jq9 by Molmil
Novel Anti-phage System
分子名称: Endonuclease GajA
著者Li, J, Wang, Z, Wang, L.
登録日2023-06-13
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8JQB
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BU of 8jqb by Molmil
Structure of Gabija GajA-GajB 4:4 Complex
分子名称: Endonuclease GajA, Gabija protein GajB
著者Li, J, Wang, Z, Wang, L.
登録日2023-06-13
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8JQC
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BU of 8jqc by Molmil
Novel Anti-phage System
分子名称: Endonuclease GajA, Gabija protein GajB
著者Li, J, Wang, Z, Wang, L.
登録日2023-06-13
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8GUG
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BU of 8gug by Molmil
Structure of VPA0770 toxin bound to VPA0769 antitoxin in Vibrio parahaemolyticus
分子名称: DUF2384 domain-containing protein, RES domain-containing protein
著者Song, X.J, Zhang, Y, Xu, Y.Y, Lin, Z.
登録日2022-09-12
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus.
Int.J.Biol.Macromol., 242, 2023
7DFE
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BU of 7dfe by Molmil
NMR structure of TuSp2-RP
分子名称: B6 protein
著者Lin, Z, Fan, T, Fan, J.
登録日2020-11-07
公開日2021-11-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H, 15N and 13C resonance assignments of a repetitive domain of tubuliform spidroin 2
Biomol.Nmr Assign., 15, 2021

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