8T4Y
 
 | | Human HCN1 F186C S264C C309A bound to cAMP, reconstituted in LMNG + SPL | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | | 登録日 | 2023-06-12 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural basis for hyperpolarization-dependent opening of human HCN1 channel.
Nat Commun, 15, 2024
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8T50
 | | Open human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Burtscher, V, Mount, J, Cowgill, J, Chang, Y, Bickel, K, Yuan, P, Chanda, B. | | 登録日 | 2023-06-12 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for hyperpolarization-dependent opening of human HCN1 channel.
Nat Commun, 15, 2024
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7UX1
 | | EcMscK in an Open Conformation | | 分子名称: | Mechanosensitive channel MscK | | 著者 | Mount, J.W, Yuan, P. | | 登録日 | 2022-05-04 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel.
Nat Commun, 13, 2022
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7UW5
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6M97
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6M98
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6BBJ
 | | Xenopus Tropicalis TRPV4 | | 分子名称: | Transient receptor potential cation channel, subfamily V, member 4 | | 著者 | Deng, Z, Hite, R.K, Yuan, P. | | 登録日 | 2017-10-18 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
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6C8G
 | | Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of barium | | 分子名称: | BARIUM ION, Transient receptor potential cation channel, subfamily V, ... | | 著者 | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | | 登録日 | 2018-01-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (6.31 Å) | | 主引用文献 | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
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6C8H
 | | Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of gadolinium | | 分子名称: | GADOLINIUM ATOM, Transient receptor potential cation channel, subfamily V, ... | | 著者 | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | | 登録日 | 2018-01-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | | 主引用文献 | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
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6CD2
 | | Crystal structure of the PapC usher bound to the chaperone-adhesin PapD-PapG | | 分子名称: | Chaperone protein PapD, Outer membrane usher protein PapC, PapGII adhesin protein | | 著者 | Omattage, N.S, Deng, Z, Yuan, P, Hultgren, S.J. | | 登録日 | 2018-02-07 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.
Nat Microbiol, 3, 2018
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6C8F
 | | Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of cesium | | 分子名称: | CESIUM ION, Transient receptor potential cation channel, subfamily V, ... | | 著者 | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | | 登録日 | 2018-01-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | | 主引用文献 | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Nat. Struct. Mol. Biol., 25, 2018
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5IT3
 | | Swirm domain of human Lsd1 | | 分子名称: | Lysine-specific histone demethylase 1A, MAGNESIUM ION | | 著者 | Jeffrey, P.D, Yuan, P. | | 登録日 | 2016-03-16 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells
To Be Published
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5KUK
 | | Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant | | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION | | 著者 | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | | 登録日 | 2016-07-13 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
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5KUM
 | | Crystal Structure of Inward Rectifier Kir2.2 K62W Mutant In Complex with PIP2 | | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DECYL-BETA-D-MALTOPYRANOSIDE, POTASSIUM ION, ... | | 著者 | Lee, S.-J, Ren, F, Heyman, S, Yuan, P, Nichols, C.G. | | 登録日 | 2016-07-13 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
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6UW6
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6UW9
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6UW4
 | | Cryo-EM structure of human TRPV3 determined in lipid nanodisc | | 分子名称: | SODIUM ION, Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Deng, Z, Yuan, P. | | 登録日 | 2019-11-04 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020
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6V6D
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6UW8
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6UZY
 | | Cryo-EM structure of Xenopus tropicalis pannexin 1 | | 分子名称: | HEXADECANE, Pannexin, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Deng, Z, He, Z, Yuan, P. | | 登録日 | 2019-11-15 | | 公開日 | 2020-04-01 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Cryo-EM structures of the ATP release channel pannexin 1.
Nat.Struct.Mol.Biol., 27, 2020
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6V5A
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6VXN
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6VXM
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6VXP
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8F7C
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