3VBO
 
 | | Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K) | | 分子名称: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | 登録日 | 2012-01-02 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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3VBH
 | | Crystal structure of formaldehyde treated human enterovirus 71 (space group R32) | | 分子名称: | CHLORIDE ION, Genome Polyprotein, capsid protein VP1, ... | | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | 登録日 | 2012-01-02 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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3VBS
 | | Crystal structure of human Enterovirus 71 | | 分子名称: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | | 登録日 | 2012-01-02 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
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8J19
 | | Cryo-EM structure of the LY237-bound GPR84 receptor-Gi complex | | 分子名称: | 6-nonylpyridine-2,4-diol, Antibody fragment ScFv16, G-protein coupled receptor 84, ... | | 著者 | Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2023-04-12 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84.
Nat Commun, 14, 2023
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8J1A
 | | Cryo-EM structure of the GPR84 receptor-Gi complex with no ligand modeled | | 分子名称: | Antibody fragment ScFv16, G-protein coupled receptor 84, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2023-04-12 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84.
Nat Commun, 14, 2023
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8J18
 | | Cryo-EM structure of the 3-OH-C12-bound GPR84 receptor-Gi complex | | 分子名称: | (3R)-3-HYDROXYDODECANOIC ACID, Antibody fragment ScFv16, G-protein coupled receptor 84, ... | | 著者 | Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2023-04-12 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84.
Nat Commun, 14, 2023
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4JGY
 | | Crystal structure of human coxsackievirus A16 uncoating intermediate (space group P4232) | | 分子名称: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | | 著者 | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, Mcauley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | | 登録日 | 2013-03-04 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Picornavirus uncoating intermediate captured in atomic detail.
Nat Commun, 4, 2013
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4JGZ
 | | Crystal structure of human coxsackievirus A16 uncoating intermediate (space group I222) | | 分子名称: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | | 著者 | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, McAuley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | | 登録日 | 2013-03-04 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Picornavirus uncoating intermediate captured in atomic detail.
Nat Commun, 4, 2013
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8H0P
 | | Structure of the NMB30-NMBR and Gq complex | | 分子名称: | G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, C, Xu, Y, Liu, H, Cai, H, Xu, H.E, Yin, W. | | 登録日 | 2022-09-30 | | 公開日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Molecular recognition of itch-associated neuropeptides by bombesin receptors
Cell Res., 33, 2023
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8H0Q
 | | Structure of the GRP14-27-GRPR-Gq complex | | 分子名称: | CHOLESTEROL, G-alpha q, GRP, ... | | 著者 | Li, C, Xu, Y, Liu, H, Cai, H, Xu, H.E, Yin, W. | | 登録日 | 2022-09-30 | | 公開日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular recognition of itch-associated neuropeptides by bombesin receptors
Cell Res., 33, 2023
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4QPG
 | | Crystal structure of empty hepatitis A virus | | 分子名称: | CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ... | | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | | 登録日 | 2014-06-23 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
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7F4H
 | | Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein, Nb35 and scFv16 | | 分子名称: | Afamelanotide, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | | 登録日 | 2021-06-18 | | 公開日 | 2021-09-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor.
Cell Res., 31, 2021
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7F4D
 | | Cryo-EM structure of alpha-MSH-bound melanocortin-1 receptor in complex with Gs protein and Nb35 | | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | | 登録日 | 2021-06-18 | | 公開日 | 2021-09-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor.
Cell Res., 31, 2021
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7F4F
 | | Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein and scFv16 | | 分子名称: | Afamelanotide, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | | 登録日 | 2021-06-18 | | 公開日 | 2021-09-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor.
Cell Res., 31, 2021
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7F4I
 | | Cryo-EM structure of SHU9119-bound melanocortin-1 receptor in complex with Gs protein and Nb35 | | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | | 登録日 | 2021-06-18 | | 公開日 | 2021-09-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor.
Cell Res., 31, 2021
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7FIJ
 | | luteinizing hormone/choriogonadotropin receptor | | 分子名称: | Lutropin-choriogonadotropic hormone receptor | | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | 登録日 | 2021-07-31 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
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7FIH
 | | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex | | 分子名称: | 5-azanyl-N-tert-butyl-2-methylsulfanyl-4-[3-(2-morpholin-4-ylethanoylamino)phenyl]thieno[2,3-d]pyrimidine-6-carboxamide, Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, ... | | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | 登録日 | 2021-07-31 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
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7FII
 | | luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex | | 分子名称: | Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, Glycoprotein hormones alpha chain, ... | | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | 登録日 | 2021-07-31 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
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7FIG
 | | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid antibody VHH fragment Nb35, Choriogonadotropin subunit beta 3, ... | | 著者 | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | 登録日 | 2021-07-31 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
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7XO4
 | | SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with two mouse ACE2 Bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2022-04-30 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
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7XOA
 | | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with one mouse ACE2 Bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2022-05-01 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
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7XO9
 | | SARS-CoV-2 Omicron BA.2 Variant RBD complexed with human ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2022-05-01 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
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7XO5
 | | SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with one mouse ACE2 Bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2022-05-01 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
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7XO7
 | | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two human ACE2 Bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2022-05-01 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
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7XOD
 | | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three JMB2002 Fab Bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of JMB2002 Fab, ... | | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | | 登録日 | 2022-05-01 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins.
Cell Res., 32, 2022
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