8J18

Cryo-EM structure of the 3-OH-C12-bound GPR84 receptor-Gi complex

Summary for 8J18

• Entry DOI: 10.2210/pdb8j18/pdb
• Related: 8J19 8J1A
• EMDB information: 35913 35914 35915
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 160585.69

Authors

Liu, H.,Yin, W.,Xu, H.E. (deposition date: 2023-04-12, release date: 2023-06-21, Last modification date: 2023-07-05)

• Primary citation: Liu, H.,Zhang, Q.,He, X.,Jiang, M.,Wang, S.,Yan, X.,Cheng, X.,Liu, Y.,Nan, F.J.,Xu, H.E.,Xie, X.,Yin, W.; Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84; Nat Commun, 14:3271-, 2023; DOI: 10.1038/s41467-023-38985-6

Experimental method

ELECTRON MICROSCOPY (2.89 Å)