3RBQ
 
 | | Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide | | 分子名称: | Guanine nucleotide-binding protein G(t) subunit alpha-1, Protein unc-119 homolog A | | 著者 | Constantine, R, Whitby, F.G, Hill, C.P, Baehr, W. | | 登録日 | 2011-03-29 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | UNC119 is required for G protein trafficking in sensory neurons.
Nat.Neurosci., 14, 2011
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6E93
 | | Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA | | 分子名称: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | | 著者 | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | | 登録日 | 2018-07-31 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | | 主引用文献 | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38.
J. Biol. Chem., 293, 2018
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6E94
 | | Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 K1055R in complex with methylated DNA | | 分子名称: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | | 著者 | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | | 登録日 | 2018-07-31 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.594 Å) | | 主引用文献 | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38.
J. Biol. Chem., 293, 2018
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1JPI
 | | Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | 登録日 | 2001-08-02 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
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1JPK
 | | Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | 登録日 | 2001-08-02 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
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1JPH
 | | Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | 登録日 | 2001-08-02 | | 公開日 | 2001-12-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
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4LCB
 | | Structure of Vps4 homolog from Acidianus hospitalis | | 分子名称: | CHLORIDE ION, Cell division protein CdvC, Vps4 | | 著者 | Han, H, Hill, C.P, Whitby, F.G, Monroe, N. | | 登録日 | 2013-06-21 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | The Oligomeric State of the Active Vps4 AAA ATPase.
J.Mol.Biol., 426, 2014
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4LGM
 | | Crystal Structure of Sulfolobus solfataricus Vps4 | | 分子名称: | CHLORIDE ION, Vps4 AAA ATPase | | 著者 | Han, H, Hill, C.P, Whitby, F.G, Monroe, N. | | 登録日 | 2013-06-28 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.711 Å) | | 主引用文献 | The Oligomeric State of the Active Vps4 AAA ATPase.
J.Mol.Biol., 426, 2014
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7TXE
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7U2V
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2Q71
 | | Uroporphyrinogen Decarboxylase G168R single mutant enzyme in complex with coproporphyrinogen-III | | 分子名称: | COPROPORPHYRINOGEN III, Uroporphyrinogen decarboxylase | | 著者 | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | | 登録日 | 2007-06-05 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Two Novel Uropophyrinogen Decarboxylase (URO-D) Mutations Causing Hepatoerythropoietic Porphyria (HEP)
Transl.Res., 149, 2007
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2Q6Z
 | | Uroporphyrinogen Decarboxylase G168R single mutant apo-enzyme | | 分子名称: | Uroporphyrinogen decarboxylase | | 著者 | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | | 登録日 | 2007-06-05 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP).
Transl.Res., 149, 2007
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7SMU
 | | Crystal Structure of Consomatin-Ro1 | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaoctatetracontane-1,48-diol, Consomatin-Ro1 | | 著者 | Ramiro, I.B.L, Whitby, F.G, Hill, C.P, Safavi-Hemami, H, Concepcion, G.P, Olivera, B.M. | | 登録日 | 2021-10-26 | | 公開日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads.
Sci Adv, 8, 2022
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3MGN
 | | D-Peptide inhibitor PIE71 in complex with IQN17 | | 分子名称: | D-PEPTIDE INHIBITOR PIE71, IQN17 | | 著者 | Hill, C.P, Whitby, F.G, Kay, M, Francis, N. | | 登録日 | 2010-04-07 | | 公開日 | 2011-03-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.
J.Virol., 84, 2010
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3OYZ
 | | Haloferax volcanii Malate Synthase Pyruvate/Acetyl-CoA Ternary Complex | | 分子名称: | ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | | 登録日 | 2010-09-24 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.
Bmc Struct.Biol., 11, 2011
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3OYX
 | | Haloferax volcanii Malate Synthase Magnesium/Glyoxylate Complex | | 分子名称: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | | 登録日 | 2010-09-24 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.
Bmc Struct.Biol., 11, 2011
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3PUG
 | | Haloferax volcanii Malate Synthase Native at 3mM Glyoxylate | | 分子名称: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | | 著者 | Howard, B.R, Bracken, C.D, Neighbor, A.M, Thomas, G.C, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | | 登録日 | 2010-12-04 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.
Bmc Struct.Biol., 11, 2011
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1JR2
 | | Structure of Uroporphyrinogen III Synthase | | 分子名称: | UROPORPHYRINOGEN-III SYNTHASE | | 著者 | Mathews, M.A, Schubert, H.L, Whitby, F.G, Alexander, K.J, Schadick, K, Bergonia, H.A, Phillips, J.D, Hill, C.P. | | 登録日 | 2001-08-10 | | 公開日 | 2001-11-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystal structure of human uroporphyrinogen III synthase.
EMBO J., 20, 2001
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1TLB
 | | Yeast coproporphyrinogen oxidase | | 分子名称: | Coproporphyrinogen III oxidase, SULFATE ION | | 著者 | Phillip, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | 登録日 | 2004-06-09 | | 公開日 | 2004-07-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the oxygen-dependent coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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1TK1
 | | YEAST OXYGEN-DEPENDENT COPROPORPHYRINOGEN OXIDASE | | 分子名称: | Coproporphyrinogen III oxidase | | 著者 | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | 登録日 | 2004-06-08 | | 公開日 | 2004-07-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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1TKL
 | | Yeast Oxygen-Dependent Coproporphyrinogen Oxidase | | 分子名称: | Coproporphyrinogen III oxidase | | 著者 | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | 登録日 | 2004-06-08 | | 公開日 | 2004-07-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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3B6H
 | | Crystal structure of human prostacyclin synthase in complex with inhibitor minoxidil | | 分子名称: | 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, ... | | 著者 | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | | 登録日 | 2007-10-29 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
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3B99
 | | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) in complex with substrate analog U51605 | | 分子名称: | (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}hept-5-enoic acid, PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | | 著者 | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | | 登録日 | 2007-11-03 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
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3B98
 | | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | | 著者 | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | | 登録日 | 2007-11-03 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
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3C3Q
 | | ALIX Bro1-domain:CHMIP4B co-crystal structure | | 分子名称: | Charged multivesicular body protein 4b peptide, GLYCEROL, Programmed cell death 6-interacting protein | | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | | 登録日 | 2008-01-28 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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