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7SAV
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BU of 7sav by Molmil
Native mu-conotoxin KIIIA isomer
分子名称: Mu-conotoxin KIIIA
著者Schroeder, C.I, Tran, H.N.T.
登録日2021-09-23
公開日2022-05-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers.
J.Biol.Chem., 298, 2022
7RZ3
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BU of 7rz3 by Molmil
The solution structure of remipede double-ICK toxin phi-Xibalbin3-Xt3a
分子名称: Xt3a
著者Maxwell, M, Chin, Y.K, Mobli, M.
登録日2021-08-27
公開日2022-08-31
最終更新日2023-03-08
実験手法SOLUTION NMR
主引用文献A bivalent remipede toxin promotes calcium release via ryanodine receptor activation.
Nat Commun, 14, 2023
7S7P
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BU of 7s7p by Molmil
NMR solution structure of a neurotoxic thionin from Urtica ferox
分子名称: urthionin-Uf1a
著者Durek, T, Harvey, P.J, Craik, D.J.
登録日2021-09-16
公開日2022-07-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox.
J.Biol.Chem., 298, 2022
6CUC
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BU of 6cuc by Molmil
Solution structure of double knot toxin (DkTx)
分子名称: Tau-theraphotoxin-Hs1a
著者Ramanujam, V, Mobli, M.
登録日2018-03-25
公開日2019-03-27
最終更新日2024-04-24
実験手法SOLUTION NMR
主引用文献Structural Basis of the Bivalency of the TRPV1 Agonist DkTx.
Angew.Chem.Int.Ed.Engl., 63, 2024
2N7F
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BU of 2n7f by Molmil
NMR solution structure of muO-conotoxin MfVIA
分子名称: muO-conotoxin MfVIA
著者Schroeder, C.I, Mobli, M.
登録日2015-09-09
公開日2016-04-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Development of a mu O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
J.Biol.Chem., 291, 2016
2N9T
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BU of 2n9t by Molmil
NMR solution structure of ProTx-II
分子名称: Beta/omega-theraphotoxin-Tp2a
著者Schroeder, C.I.
登録日2015-12-08
公開日2016-07-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
J.Biol.Chem., 291, 2016
2MT7
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BU of 2mt7 by Molmil
Solution structure of spider-venom peptide Hs1a
分子名称: Hs1a
著者Klint, J.K, King, G.F, Mobli, M.
登録日2014-08-14
公開日2015-08-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Nav1.7 inhibitors normalise mechanical responses in chronic visceral hypersensitivity
To be Published
2MXM
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BU of 2mxm by Molmil
NMR solution structure of TRTX-Tp1a from the tarantula Thrixopelma pruriens
分子名称: entity
著者Rosengren, K.
登録日2015-01-08
公開日2015-06-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification and Characterization of ProTx-III [ mu-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
Mol.Pharmacol., 88, 2015
2MPQ
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BU of 2mpq by Molmil
Solution structure of the sodium channel toxin Hd1a
分子名称: Hd1a
著者Klint, J.K, Mobli, M, King, G.F.
登録日2014-06-01
公開日2015-03-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.
Br.J.Pharmacol., 172, 2015
2KRA
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BU of 2kra by Molmil
Solution structure of Bv8
分子名称: Prokineticin Bv8
著者Daly, N.L, Craik, D.J, Mobli, M.
登録日2009-12-14
公開日2010-08-11
最終更新日2014-04-23
実験手法SOLUTION NMR
主引用文献Chemical synthesis and structure of the prokineticin Bv8
CHEMBIOCHEM, 11, 2010
4HHF
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BU of 4hhf by Molmil
Crystal Structure of chemically synthesized scorpion alpha-toxin OD1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-toxin OD1
著者Wang, C.I.A, Lewis, R.J, Alewood, P.F, Durek, T.
登録日2012-10-09
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
Acs Chem.Biol., 8, 2013
8BWF
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BU of 8bwf by Molmil
PTBP1 RRM1 bound to an allosteric inhibitor
分子名称: AMINO GROUP, GLYCEROL, Ligand, ...
著者Schmeing, S, Vetter, I, t Hart, P, Gasper, R.
登録日2022-12-06
公開日2023-10-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.
Chem Sci, 14, 2023
3T5D
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BU of 3t5d by Molmil
Crystal structure of Septin 7 in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Septin-7
著者Zent, E, Wittinghofer, A.
登録日2011-07-27
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and biochemical properties of Sept7, a unique septin required for filament formation.
Biol.Chem., 392, 2011
1PRE
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BU of 1pre by Molmil
PROAEROLYSIN
分子名称: PROAEROLYSIN
著者Parker, M.W, Buckley, J.T, Postma, J.P.M, Tucker, A.D, Tsernoglou, D.
登録日1995-09-15
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states.
Nature, 367, 1994
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