1W19
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![BU of 1w19 by Molmil](/molmil-images/mine/1w19) | Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)propane 1-phosphate | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (4S,5S)-1,2-DITHIANE-4,5-DIOL, ... | 著者 | Morgunova, E, Meining, W, Illarionov, B, Haase, I, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | 登録日 | 2004-06-03 | 公開日 | 2005-03-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,) Biochemistry, 44, 2005
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1MNT
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![BU of 1mnt by Molmil](/molmil-images/mine/1mnt) | SOLUTION STRUCTURE OF DIMERIC MNT REPRESSOR (1-76) | 分子名称: | MNT REPRESSOR | 著者 | Burgering, M.J.M, Boelens, R, Gilbert, D.E, Breg, J.N, Knight, K.L, Sauer, R.T, Kaptein, R. | 登録日 | 1994-06-28 | 公開日 | 1994-09-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of dimeric Mnt repressor (1-76). Biochemistry, 33, 1994
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1EJB
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![BU of 1ejb by Molmil](/molmil-images/mine/1ejb) | LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE | 分子名称: | 5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID, LUMAZINE SYNTHASE | 著者 | Meining, W, Mortl, S, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | 登録日 | 2000-03-02 | 公開日 | 2001-03-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue. J.Mol.Biol., 299, 2000
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5WJD
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![BU of 5wjd by Molmil](/molmil-images/mine/5wjd) | Crystal structure of Naa80 bound to acetyl-CoA | 分子名称: | ACETYL COENZYME *A, CG8481, isoform B, ... | 著者 | Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T. | 登録日 | 2017-07-21 | 公開日 | 2018-03-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7MX2
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2GEQ
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![BU of 2geq by Molmil](/molmil-images/mine/2geq) | Crystal Structure of a p53 Core Dimer Bound to DNA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*CP*GP*TP*GP*AP*GP*CP*AP*TP*GP*CP*TP*CP*AP*C)-3', Cellular tumor antigen p53, ... | 著者 | Ho, W.C, Fitzgerald, M.X, Marmorstein, R. | 登録日 | 2006-03-20 | 公開日 | 2006-05-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the p53 Core Domain Dimer Bound to DNA. J.Biol.Chem., 281, 2006
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1MQX
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![BU of 1mqx by Molmil](/molmil-images/mine/1mqx) | NMR Solution Structure of Type-B Lantibiotics Mersacidin in MeOH/H2O Mixture | 分子名称: | LANTIBIOTIC MERSACIDIN | 著者 | Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M. | 登録日 | 2002-09-17 | 公開日 | 2003-03-11 | 最終更新日 | 2024-07-10 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity J.Biol.Chem., 278, 2003
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1N1Q
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![BU of 1n1q by Molmil](/molmil-images/mine/1n1q) | Crystal structure of a Dps protein from Bacillus brevis | 分子名称: | DPS Protein, MU-OXO-DIIRON | 著者 | Ren, B, Tibbelin, G, Kajino, T, Asami, O, Ladenstein, R. | 登録日 | 2002-10-19 | 公開日 | 2003-05-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Multi-layered Structure of Dps with a Novel Di-nuclear Ferroxidase Center J.Mol.Biol., 329, 2003
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1MQZ
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![BU of 1mqz by Molmil](/molmil-images/mine/1mqz) | NMR solution structure of type-B lantibiotics mersacidin bound to lipid II in DPC micelles | 分子名称: | LANTIBIOTIC MERSACIDIN | 著者 | Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M. | 登録日 | 2002-09-17 | 公開日 | 2003-03-11 | 最終更新日 | 2024-07-10 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity J.Biol.Chem., 278, 2003
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1MQY
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![BU of 1mqy by Molmil](/molmil-images/mine/1mqy) | NMR solution structure of type-B lantibiotics mersacidin in DPC micelles | 分子名称: | LANTIBIOTIC MERSACIDIN | 著者 | Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M. | 登録日 | 2002-09-17 | 公開日 | 2003-03-11 | 最終更新日 | 2024-07-10 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity J.Biol.Chem., 278, 2003
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2RC4
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![BU of 2rc4 by Molmil](/molmil-images/mine/2rc4) | Crystal Structure of the HAT domain of the human MOZ protein | 分子名称: | ACETYL COENZYME *A, Histone acetyltransferase MYST3, ZINC ION | 著者 | Holbert, M.A, Sikorski, T, Snowflack, D, Marmorstein, R. | 登録日 | 2007-09-19 | 公開日 | 2007-11-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting. J.Biol.Chem., 282, 2007
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4PO2
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![BU of 4po2 by Molmil](/molmil-images/mine/4po2) | Crystal Structure of the Stress-Inducible Human Heat Shock Protein HSP70 Substrate-Binding Domain in Complex with Peptide Substrate | 分子名称: | HSP70 substrate peptide, Heat shock 70 kDa protein 1A/1B, PHOSPHATE ION, ... | 著者 | Zhang, P, Leu, J.I, Murphy, M.E, George, D.L, Marmorstein, R. | 登録日 | 2014-02-24 | 公開日 | 2014-08-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with Peptide substrate. Plos One, 9, 2014
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4V7G
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![BU of 4v7g by Molmil](/molmil-images/mine/4v7g) | Crystal Structure of Lumazine Synthase from Bacillus Anthracis | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION | 著者 | Morgunova, E, Illarionov, B, Saller, S, Popov, A, Sambaiah, T, Bacher, A, Cushman, M, Fischer, M, Ladenstein, R. | 登録日 | 2009-09-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracis. Acta Crystallogr.,Sect.D, 66, 2010
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4PZT
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![BU of 4pzt by Molmil](/molmil-images/mine/4pzt) | Crystal structure of p300 histone acetyltransferase domain in complex with an inhibitor, Acetonyl-Coenzyme A | 分子名称: | DIMETHYL SULFOXIDE, Histone acetyltransferase p300, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-2,2-DIMETHYL-4-OXO-4-{[3-OXO-3-({2-[(2-OXOPROPYL)THIO]ETHYL}AMINO)PROPYL]AMINO}BUTYL DIHYDROGEN DIPHOSPHATE | 著者 | Maksimoska, J, Marmorstein, R. | 登録日 | 2014-03-31 | 公開日 | 2014-06-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues. Biochemistry, 53, 2014
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5ICV
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![BU of 5icv by Molmil](/molmil-images/mine/5icv) | Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue | 分子名称: | MET-LYS-ALA-VAL-LIG, N-alpha-acetyltransferase 60, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate | 著者 | Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T. | 登録日 | 2016-02-23 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation. Structure, 24, 2016
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6POE
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6POF
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6PPL
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6PW9
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![BU of 6pw9 by Molmil](/molmil-images/mine/6pw9) | Cryo-EM structure of human NatE/HYPK complex | 分子名称: | ACETYL COENZYME *A, Huntingtin-interacting protein K, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Deng, S, Marmorstein, R. | 登録日 | 2019-07-22 | 公開日 | 2020-02-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK. Nat Commun, 11, 2020
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8ARV
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5WJE
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![BU of 5wje by Molmil](/molmil-images/mine/5wje) | Crystal structure of Naa80 bound to a bisubstrate analogue | 分子名称: | Actin N-terminus peptide, CARBOXYMETHYL COENZYME *A, CG8481, ... | 著者 | Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T. | 登録日 | 2017-07-21 | 公開日 | 2018-03-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.765 Å) | 主引用文献 | Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6O07
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6UV5
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6UUW
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![BU of 6uuw by Molmil](/molmil-images/mine/6uuw) | Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA | 分子名称: | (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | 著者 | Wei, X, Marmorstein, R. | 登録日 | 2019-11-01 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27, 2020
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6VP9
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![BU of 6vp9 by Molmil](/molmil-images/mine/6vp9) | Cryo-EM structure of human NatB complex | 分子名称: | CARBOXYMETHYL COENZYME *A, MDVFM peptide, N-alpha-acetyltransferase 20, ... | 著者 | Deng, S, Marmorstein, R. | 登録日 | 2020-02-02 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Molecular basis for N-terminal alpha-synuclein acetylation by human NatB. Elife, 9, 2020
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