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5WGQ
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Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-BCP1
分子名称: ESTRADIOL, Estrogen receptor, SRC2-BCP1
著者Fanning, S.W, Speltz, T.E, Mayne, C.G, Siddiqui, Z, Greene, G.L, Tajkhorshid, E, Moore, T.W.
登録日2017-07-14
公開日2018-06-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A "cross-stitched" peptide with improved helicity and proteolytic stability.
Org. Biomol. Chem., 16, 2018
7NHQ
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Structure of PSII-I prime (PSII with Psb28, and Psb34)
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
登録日2021-02-11
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
7NHP
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Structure of PSII-I (PSII with Psb27, Psb28, and Psb34)
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
登録日2021-02-11
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
7NHO
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BU of 7nho by Molmil
Structure of PSII-M
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M.
登録日2021-02-11
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural insights into photosystem II assembly.
Nat.Plants, 7, 2021
1LDF
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BU of 1ldf by Molmil
CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) MUTATION W48F, F200T
分子名称: GLYCEROL, Glycerol uptake facilitator protein, MAGNESIUM ION, ...
著者Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M.
登録日2002-04-08
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
1LDA
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CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL
分子名称: Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside
著者Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M.
登録日2002-04-08
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
1LDI
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CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL
分子名称: Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside
著者Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M.
登録日2002-04-08
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
4XI3
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BU of 4xi3 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain in Complex with Bazedoxifene
分子名称: Bazedoxifene, Estrogen receptor
著者Fanning, S.W, Mayne, C.G, Toy, W, Carlson, K, Greene, B, Nowak, J, Walter, R, Panchamukhi, S, Tajhorshid, E, Nettles, K.W, Chandarlapaty, S, Katzenellenbogen, J, Greene, G.L.
登録日2015-01-06
公開日2016-01-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.491 Å)
主引用文献The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Elife, 7, 2018
6RHY
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BU of 6rhy by Molmil
Structure of pore-forming amyloid-beta tetramers
分子名称: Amyloid beta A4 protein
著者Bardiaux, B, Ciudad, S, Carulla, N.
登録日2019-04-23
公開日2019-09-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A beta (1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage.
Nat Commun, 11, 2020
6DZY
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BU of 6dzy by Molmil
Cryo-EM structure of the ts2-active human serotonin transporter in complex with 15B8 Fab and 8B6 ScFv bound to ibogaine
分子名称: (5beta)-12-methoxyibogamine, 15B8 antibody heavy chain, 15B8 antibody light chain, ...
著者Coleman, J.A, Yang, D, Gouaux, E.
登録日2018-07-05
公開日2019-04-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
6DZV
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BU of 6dzv by Molmil
Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in occluded conformation
分子名称: (5beta)-12-methoxyibogamine, 15B8 antibody heavy chain, 15B8 antibody light chain, ...
著者Coleman, J.A, Yang, D, Gouaux, E.
登録日2018-07-05
公開日2019-04-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
6DZZ
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BU of 6dzz by Molmil
Cryo-EM Structure of the wild-type human serotonin transporter in complex with ibogaine and 15B8 Fab in the inward conformation
分子名称: (5beta)-12-methoxyibogamine, 15B8 antibody heavy chain, 15B8 antibody light chain, ...
著者Yang, D, Coleman, J.A, Gouaux, E.
登録日2018-07-05
公開日2019-04-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
6DZW
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BU of 6dzw by Molmil
Cryo-EM structure of the ts2-inactive human serotonin transporter in complex with paroxetine and 15B8 Fab and 8B6 ScFv
分子名称: 15B8 antibody heavy chain, 15B8 antibody light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Coleman, J.A, Yang, D, Gouaux, E.
登録日2018-07-05
公開日2019-04-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
5XLS
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BU of 5xls by Molmil
Crystal structure of UraA in occluded conformation
分子名称: 12-TUNGSTOPHOSPHATE, URACIL, Uracil permease
著者Yu, X.Z, Yang, G.H, Yan, C.Y, Yan, N.
登録日2017-05-11
公開日2017-07-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters
Cell Res., 27, 2017
4EZC
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BU of 4ezc by Molmil
Crystal Structure of the UT-B Urea Transporter from Bos Taurus
分子名称: OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ...
著者Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2012-05-02
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EZD
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BU of 4ezd by Molmil
Crystal Structure of the UT-B Urea Transporter from Bos Taurus Bound to Selenourea
分子名称: OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ...
著者Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2012-05-02
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and permeation mechanism of a mammalian urea transporter.
Proc.Natl.Acad.Sci.USA, 109, 2012
7USX
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Structure of Contracted C. elegans TMC-1 complex
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jeong, H, Clark, S, Gouaux, E.
登録日2022-04-26
公開日2022-10-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
7USW
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Structure of Expanded C. elegans TMC-1 complex
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jeong, H, Clark, S, Gouaux, E.
登録日2022-04-26
公開日2022-10-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
7USY
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Structure of C. elegans TMC-1 complex with ARRD-6
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jeong, H, Clark, S, Gouaux, E.
登録日2022-04-26
公開日2022-10-19
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
8FMV
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BU of 8fmv by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-2HT/ATP
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Tang, Q, Mchaourab, H.
登録日2022-12-24
公開日2023-11-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8FHK
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Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ATP: BmrCD_OC-ATP
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Tang, Q, Mchaourab, H.
登録日2022-12-14
公開日2023-11-15
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
6OL1
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Structure of VcINDY in complex with Succinate
分子名称: SODIUM ION, SUCCINIC ACID, Transporter, ...
著者Sauer, D.B, Marden, J.J, Wang, D.N.
登録日2019-04-15
公開日2020-10-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.088 Å)
主引用文献Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
Biorxiv, 2022
6D9G
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BU of 6d9g by Molmil
X-ray Structure of the FAB Fragment of 15B8, a Murine Monoclonal Antibody Specific for the Human Serotonin Transporter
分子名称: Antibody heavy chain Fab, Antibody light chain Fab
著者Coleman, J.A, Yang, D, Gouaux, E.
登録日2018-04-29
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
1Z98
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BU of 1z98 by Molmil
Crystal structure of the spinach aquaporin SoPIP2;1 in a closed conformation
分子名称: CADMIUM ION, aquaporin
著者Tornroth-Horsefield, S, Hedfalk, K, Johanson, U, Karlsson, M, Neutze, R, Kjellbom, P.
登録日2005-04-01
公開日2005-12-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural mechanism of plant aquaporin gating
Nature, 439, 2006
5HD8
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BU of 5hd8 by Molmil
Crystal structure of disulfide cross-linked D417C ClC-ec1
分子名称: CHLORIDE ION, FAB FRAGMENT (HEAVY CHAIN), FAB FRAGMENT (LIGHT CHAIN), ...
著者Mathews, I.I, Khantwal, C.M, Maduke, M.
登録日2016-01-05
公開日2017-01-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Conformational change in CLC transporters: beyond the rotation of Gluex
To be published

221051

件を2024-06-12に公開中

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