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CryoEM structure of DH270.I1.6-CH848.10.17
分子名称:	CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, DH270.I1.6 variable heavy chain, ...
著者	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日	2023-04-02
公開日	2023-04-19
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB2

CryoEM structure of DH270.I2-CH848.10.17
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
著者	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日	2023-04-02
公開日	2023-04-19
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (3.5 Å)
主引用文献	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB0

CryoEM structure of DH270.I4.6-CH848.10.17
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
著者	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日	2023-04-02
公開日	2023-04-19
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

8SB1

CryoEM structure of DH270.I3-CH848.10.17
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17.SOSIP gp41, ...
著者	Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日	2023-04-02
公開日	2023-04-19
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (4.3 Å)
主引用文献	Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023

6XRJ

Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
分子名称:	DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
著者	Manne, K, Nicely, N.I, Acharya, P.
登録日	2020-07-13
公開日	2020-12-30
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.15 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

8CSA

Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)
分子名称:	Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2022-05-12
公開日	2022-07-20
最終更新日	2024-01-31
実験手法	ELECTRON MICROSCOPY (3.84 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity Science, 2021

7SG4

Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
著者	Gobeil, S, Acharya, P.
登録日	2021-10-04
公開日	2021-11-10
最終更新日	2022-02-09
実験手法	ELECTRON MICROSCOPY (3.43 Å)
主引用文献	A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice. Sci Transl Med, 14, 2022

7LYK

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (3.65 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYQ

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (3.34 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYL

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (3.72 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYO

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (3.32 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYP

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (4.05 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LYN

South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-07
公開日	2021-03-31
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (3.32 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

6X2A

SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
分子名称:	Spike glycoprotein
著者	Henderson, R, Acharya, P.
登録日	2020-05-20
公開日	2020-05-27
最終更新日	2021-08-04
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X2B

SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
分子名称:	Spike glycoprotein
著者	Henderson, R, Acharya, P.
登録日	2020-05-20
公開日	2020-05-27
最終更新日	2021-08-04
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X29

SARS-CoV-2 rS2d Down State Spike Protein Trimer
分子名称:	Spike glycoprotein
著者	Henderson, R, Acharya, P.
登録日	2020-05-20
公開日	2020-05-27
最終更新日	2020-10-21
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

6X2C

SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
分子名称:	Spike glycoprotein
著者	Henderson, R, Acharya, P.
登録日	2020-05-20
公開日	2020-05-27
最終更新日	2021-07-07
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Controlling the SARS-CoV-2 spike glycoprotein conformation. Nat.Struct.Mol.Biol., 27, 2020

7LD1

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-12
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LCN

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1050.1 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-11
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.35 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LAB

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-06
公開日	2021-03-10
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.97 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LAA

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1041 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-06
公開日	2021-03-17
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.42 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

8U1D

Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env Local Refinement
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1285 Heavy Chain, DH1285 Light Chain, ...
著者	Thakur, B, Stalls, V.D, Acharya, P.
登録日	2023-08-31
公開日	2024-01-03
最終更新日	2024-07-17
実験手法	ELECTRON MICROSCOPY (4.25 Å)
主引用文献	Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques. Cell, 187, 2024

7THT

CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 heavy chain, ...
著者	Manne, K, May, A, Acharya, P.
登録日	2022-01-12
公開日	2022-02-16
最終更新日	2023-04-12
実験手法	ELECTRON MICROSCOPY (3.42 Å)
主引用文献	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

8DKF

Antibody DH1030.1 Fab fragment
分子名称:	DH1030.1 Heavy chain, DH1030.1 Light chain
著者	Gobeil, S, Acharya, P.
登録日	2022-07-05
公開日	2023-07-12
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.79 Å)
主引用文献	DH1030.1 glycan reactive Ab To Be Published

8DP1

Cryo-EM structure of HIV-1 Env(BG505.T332N SOSIP) in complex with DH1030.1 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1030.1 Fab Heavy chain, ...
著者	Gobeil, S, Acharya, P.
登録日	2022-07-14
公開日	2023-07-19
実験手法	ELECTRON MICROSCOPY (3.46 Å)
主引用文献	Shared recognition mechanism for HIV-1 envelope-reactive V3 glycan broadly neutralizing B cell lineage maturation in humans and macaques To Be Published

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