5CVC
 
 | | Structure of maize serine racemase | | 分子名称: | MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Serine racemase | | 著者 | Song, Y, Zou, L, Fan, J. | | 登録日 | 2015-07-26 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Crystal structure of maize serine racemase with pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.F, 72, 2016
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7Y6D
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5YHY
 | | Structure of Lactococcus lactis ZitR, C30S mutant | | 分子名称: | ZINC ION, Zinc transport transcriptional regulator | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5YHZ
 | | Structure of Lactococcus lactis ZitR, E41A mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ZINC ION, ... | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5YI3
 | | Structure of Lactococcus lactis ZitR, C30S mutant in complex with DNA | | 分子名称: | DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION, Zinc transport transcriptional regulator | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5YHX
 | | Structure of Lactococcus lactis ZitR, wild type | | 分子名称: | ZINC ION, Zinc transport transcriptional regulator | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5YI0
 | | Structure of Lactococcus lactis ZitR, C30AH42A mutant | | 分子名称: | ZINC ION, Zinc transport transcriptional regulator | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5YI1
 | | Structure of Lactococcus lactis ZitR, C30AH42A mutant in apo form | | 分子名称: | Zinc transport transcriptional regulator | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5YI2
 | | Structure of Lactococcus lactis ZitR, wild type in complex with DNA | | 分子名称: | DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION, Zinc transport transcriptional regulator | | 著者 | Song, Y, Liu, H, Zhu, R, Yi, C, Chen, P. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
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5XOR
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7AGQ
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7AKC
 | | Structure of the of AcylTransferase domain of phenolphthiocerol/phtiocerol synthase A from Mycobacterium bovis (BCG) | | 分子名称: | Phenolpthiocerol synthesis type-I polyketide synthase ppsA, SODIUM ION | | 著者 | Brison, Y, Nahoum, V, Mourey, L, Maveyraud, L. | | 登録日 | 2020-09-30 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15, 2020
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7AGU
 | | Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated with MethylMalonyl-coenzyme A | | 分子名称: | 1,2-ETHANEDIOL, METHYLMALONIC ACID, Mycocerosic acid synthase | | 著者 | Brison, Y, Mourey, L, Maveyraud, L. | | 登録日 | 2020-09-23 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15, 2020
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7AGT
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7AGR
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7AGS
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7AGP
 | | Structure of the AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis | | 分子名称: | 1,2-ETHANEDIOL, Mycocerosic acid synthase | | 著者 | Brison, Y, Nahoum, V, Mourey, L, Maveyraud, L. | | 登録日 | 2020-09-23 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15, 2020
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5V58
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5V59
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6R8I
 | | PP4R3A EVH1 domain bound to FxxP motif | | 分子名称: | SER-LEU-PRO-PHE-THR-PHE-LYS-VAL-PRO-ALA-PRO-PRO-PRO-SER-LEU-PRO-PRO-SER, Serine/threonine-protein phosphatase 4 regulatory subunit 3A | | 著者 | Ueki, Y, Kruse, T, Weisser, M.B, Sundell, G.N, Yoo Larsen, M.S, Lopez Mendez, B, Jenkins, N.P, Garvanska, D.H, Cressey, L, Zhang, G, Davey, N, Montoya, G, Ivarsson, Y, Kettenbach, A, Nilsson, J. | | 登録日 | 2019-04-02 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.517 Å) | | 主引用文献 | A Consensus Binding Motif for the PP4 Protein Phosphatase.
Mol.Cell, 76, 2019
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4PM0
 | | PDE7A catalytic domain in complex with 2-(Cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivative | | 分子名称: | 2-(cyclopentylamino)-3-ethyl-7-ethynylthieno[3,2-d]pyrimidin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | | 著者 | Kawai, K, Endo, Y, Asano, T, Amano, S, Sawada, K, Ueo, N, Takahashi, N, Sonoda, Y, Kamei, N, Nagata, N. | | 登録日 | 2014-05-20 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery of 2-(Cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one Derivatives as a New Series of Potent Phosphodiesterase 7 Inhibitors.
J.Med.Chem., 57, 2014
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5HS5
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7S82
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7ZX4
 | | Clathrin N-terminal domain in complex with a HURP phospho-peptide | | 分子名称: | CHLORIDE ION, Clathrin heavy chain 1, Disks large-associated protein 5, ... | | 著者 | Kliche, J, Badgujar, D, Dobritzsch, D, Ivarsson, Y. | | 登録日 | 2022-05-20 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Mol.Syst.Biol., 19, 2023
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4Y2B
 | | Co-crystal structure of 3-ethyl-2-(isopropylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one bound to PDE7A | | 分子名称: | 3-ethyl-2-(propan-2-ylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | | 著者 | Endo, Y, Kawai, K, Asano, T, Amano, S, Asanuma, Y, Sawada, K, Onodera, Y, Ueo, N, Takahashi, N, Sonoda, Y, Kamei, N, Irie, T. | | 登録日 | 2015-02-09 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | 2-(Isopropylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as selective phosphodiesterase 7 inhibitors with potent in vivo efficacy
Bioorg.Med.Chem.Lett., 25, 2015
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