3VLX
 
 | | Assimilatory nitrite reductase (Nii3) - N226K mutant - ligand free form from tobacco leaf | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ... | | 著者 | Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K. | | 登録日 | 2011-12-05 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | X-ray crystal structure of a mutant assimilatory nitrite reductase that shows sulfite reductase-like activity
Chem.Biodivers., 9, 2012
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1WTG
 | | Human Factor Viia-Tissue Factor Complexed with ethylsulfonamide-D-biphenylalanine-Gln-p-aminobenzamidine | | 分子名称: | 2-(3-BIPHENYL-4-YL-2-ETHANESULFONYLAMINO-PROPIONYLAMINO)-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE), CALCIUM ION, Coagulation factor VII, ... | | 著者 | Kadono, S, Sakamoto, S, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Kitazawa, K, Yoshihashi, T, Suzuki, T, Koga, T, Hattori, K, Shiraishi, T, Kodama, M, Haramura, H, Ono, Y, Esaki, T, Sato, H, Watanabe, Y, Itoh, S, Ohta, M, Kozono, T. | | 登録日 | 2004-11-23 | | 公開日 | 2005-11-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor
Biochem.Biophys.Res.Commun., 326, 2005
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7D45
 | | eIF2B-eIF2(aP), aP1 complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2020-09-22 | | 公開日 | 2020-12-09 | | 最終更新日 | 2021-01-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol.Cell, 81, 2021
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7D44
 | | eIF2B-eIF2(aP), aP2 complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2020-09-22 | | 公開日 | 2020-12-09 | | 最終更新日 | 2021-01-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol.Cell, 81, 2021
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7D46
 | | eIF2B apo | | 分子名称: | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2020-09-22 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol.Cell, 81, 2021
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7D43
 | | eIF2B-eIF2(aP), aPg complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2020-09-22 | | 公開日 | 2020-12-09 | | 最終更新日 | 2021-01-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol.Cell, 81, 2021
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7VLK
 | | eIF2B-SFSV NSs C2-imposed | | 分子名称: | Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-10-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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1IXD
 | | Solution structure of the CAP-GLY domain from human cylindromatosis tomour-suppressor CYLD | | 分子名称: | Cylindromatosis tumour-suppressor CYLD | | 著者 | Saito, K, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-06-19 | | 公開日 | 2002-12-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The CAP-Gly domain of CYLD associates with the proline-rich sequence in NEMO/IKKgamma
STRUCTURE, 12, 2004
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5B71
 | | Crystal structure of complement C5 in complex with SKY59 | | 分子名称: | Complement C5 beta chain, SKY59 Fab heavy chain, SKY59 Fab light chain | | 著者 | Irie, M, Shimizu, Y, Sampei, Z, Fukuzawa, T. | | 登録日 | 2016-06-03 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases.
Sci Rep, 7, 2017
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7F66
 | | eIF2B-SFSV NSs-1-eIF2 | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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7F67
 | | eIF2B-SFSV NSs-2-eIF2 | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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7F64
 | | eIF2B-SFSV NSs | | 分子名称: | Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-24 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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6JLZ
 | | P-eIF2a - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, PHOSPHATE ION, Probable translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2019-03-07 | | 公開日 | 2019-05-01 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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6JLY
 | | eIF2a - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, PHOSPHATE ION, Probable translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2019-03-07 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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6IP8
 | | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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6IP6
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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6K72
 | | eIF2(aP) - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Kashiwagi, K, Yokoyama, T, Ito, T. | | 登録日 | 2019-06-05 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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6IP5
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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6K71
 | | eIF2 - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Kashiwagi, K, Yokoyama, T, Ito, T. | | 登録日 | 2019-06-05 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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2DX1
 | | Crystal structure of RhoGEF protein Asef | | 分子名称: | Rho guanine nucleotide exchange factor 4 | | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-22 | | 公開日 | 2007-01-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism
J.Biol.Chem., 282, 2007
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3ADE
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