6HVO
 
 | | Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta | | 分子名称: | DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION | | 著者 | Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-10-11 | | 公開日 | 2019-01-23 | | 最終更新日 | 2019-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
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8ABQ
 | | Structure of the SNX1-SNX5 complex, Pt derivative | | 分子名称: | PLATINUM (II) ION, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E.N, Banos-Mateos, S, Vidaurrazaga, A, Rojas, A.L, Castano, D, Hierro, A. | | 登録日 | 2022-07-04 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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8AFZ
 | | Architecture of the ESCPE-1 membrane coat | | 分子名称: | Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5 | | 著者 | Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A. | | 登録日 | 2022-07-18 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
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8ASA
 | | Crystal structure of AO75L | | 分子名称: | 1,2-ETHANEDIOL, BICINE, CALCIUM ION, ... | | 著者 | Laugeri, M.E, Speciale, I, Gimeno, A, Lin, S, Poveda, A, Lowary, T, Van Etten, J.L, Barbero, J.J, De Castro, C, Tonetti, M, Rojas, A.L. | | 登録日 | 2022-08-18 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of AO75L
To Be Published
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8AVQ
 | | AO75L in Complex with UDP-Xylose | | 分子名称: | 1,2-ETHANEDIOL, AO75L, BICINE, ... | | 著者 | Laugeri, M.E, Speciale, I, Gimeno, A, Lin, S, Poveda, A, Lowary, T, Van Etten, J.L, Barbero, J.J, De Castro, C, Tonetti, M, Rojas, A.L. | | 登録日 | 2022-08-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | AO75L in Complex with UDP-Xylose
To Be Published
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5OSI
 | | Structure of retromer VPS29-VPS35C subunits complexed with RidL harpin loop (163-176) | | 分子名称: | 1,2-ETHANEDIOL, Interaptin, SODIUM ION, ... | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OSH
 | | Structure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236) | | 分子名称: | Interaptin, Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OT4
 | | Structure of the Legionella pneumophila effector RidL (1-866) | | 分子名称: | GLYCEROL, Interaptin | | 著者 | Romano-Moreno, M, Rojas, A.L, Lucas, M, Isupov, M.N, Hierro, A. | | 登録日 | 2017-08-20 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5N35
 | | Gadolinium phased PBP2 (SSO6202) at 2.2 Ang | | 分子名称: | GADOLINIUM ATOM, GLYCEROL, NITRATE ION, ... | | 著者 | Yan, J, Beattie, T.R, Rojas, A.L, Schermerhorn, K, Gristwood, T, Trinidad, J.C, Albers, S.V, Roversi, P, Gardner, A.F, Abrescia, N.G.A, Bell, S.D. | | 登録日 | 2017-02-08 | | 公開日 | 2017-05-17 | | 最終更新日 | 2017-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.
Nat Commun, 8, 2017
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5A1I
 | | The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP. | | 分子名称: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, 1,2-ETHANEDIOL, ADENOSINE, ... | | 著者 | Murray, B, Antonyuk, S.V, Marina, A, Lu, S.C, Mato, J.M, Hasnain, S.S, Rojas, A.L. | | 登録日 | 2015-04-30 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5A1G
 | | The structure of Human MAT2A in complex with S-adenosylethionine and PPNP. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, IMIDAZOLE, ... | | 著者 | Murray, B, Antonyuk, S.V, Marina, A, Lu, S.C, Mato, J.M, Hasnain, S.S, Rojas, A.L. | | 登録日 | 2015-04-30 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5A19
 | | The structure of MAT2A in complex with PPNP. | | 分子名称: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Murray, B, Antonyuk, S.V, Marina, A, Lu, S.C, Mato, J.M, Hasnain, S.S, Rojas, A.L. | | 登録日 | 2015-04-28 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F0J
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0L
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0K
 | | Structure of VPS35 N terminal region | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.074 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0M
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 (SeMet labeled) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5F0P
 | | Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Natural resistance-associated macrophage protein 2, ... | | 著者 | Lucas, M, Gershlick, D, Vidaurrazaga, A, Rojas, A.L, Bonifacino, J.S, Hierro, A. | | 登録日 | 2015-11-27 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell, 167, 2016
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5M3D
 | | Structural tuning of CD81LEL (space group P31) | | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen, PHOSPHATE ION | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-14 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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5LJI
 | | Streptococcus pneumonia TIGR4 flavodoxin: structural and biophysical characterization of a novel drug target | | 分子名称: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, Flavodoxin | | 著者 | Rodriguez-Cardenas, A, Rojas, A.L, Velazquez-Campoy, A, Hurtado-Guerrero, R, Sancho, J. | | 登録日 | 2016-07-18 | | 公開日 | 2016-08-31 | | 最終更新日 | 2016-09-28 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target.
Plos One, 11, 2016
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5M4R
 | | Structural tuning of CD81LEL (space group C2) | | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen, SULFATE ION | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-19 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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5M2C
 | | Structural tuning of CD81LEL (space group P32 1 2) | | 分子名称: | CD81 antigen, PHOSPHATE ION | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-12 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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5M6R
 | | Human porphobilinogen deaminase in complex with reaction intermediate | | 分子名称: | 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHOSPHATE ION, ... | | 著者 | Pluta, P, Millet, O, Roversi, P, Rojas, A.L, Gu, S. | | 登録日 | 2016-10-25 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Structural basis of pyrrole polymerization in human porphobilinogen deaminase.
Biochim Biophys Acta Gen Subj, 1862, 2018
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5ME8
 | | N-terminal domain of the human tumor suppressor ING5 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5 | | 著者 | Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R. | | 登録日 | 2016-11-14 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
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5MTO
 | | N-terminal domain of the human tumor suppressor ING5 C19S mutant | | 分子名称: | Inhibitor of growth protein 5, SODIUM ION, SULFATE ION | | 著者 | Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J. | | 登録日 | 2017-01-10 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
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5M7F
 | | Human porphobilinogen deaminase in complex with DPM cofactor | | 分子名称: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase, SULFATE ION | | 著者 | Pluta, P, Millet, O, Roversi, P, Rojas, A.L, Gu, S. | | 登録日 | 2016-10-27 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structural basis of pyrrole polymerization in human porphobilinogen deaminase.
Biochim Biophys Acta Gen Subj, 1862, 2018
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