5A19

The structure of MAT2A in complex with PPNP.

Summary for 5A19

Related5A1G 5A1I
DescriptorS-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2, DI(HYDROXYETHYL)ETHER, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, ... (8 entities in total)
Functional Keywordstransferase, methionine adenosyltransferase, cell growth, liver cancer, methylation.
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total molecular weight44721.77
Authors
Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L. (deposition date: 2015-04-28, release date: 2016-02-17, Last modification date: 2016-03-09)
Primary citation
Murray, B.,Antonyuk, S.V.,Marina, A.,Lu, S.C.,Mato, J.M.,Hasnain, S.S.,Rojas, A.L.
Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
Proc.Natl.Acad.Sci.USA, 113:2104-, 2016
PubMed: 26858410 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.1510959113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.34 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20810 1.6% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170172
PDB entries from 2020-10-21