2BLN
 
 | | N-terminal formyltransferase domain of ArnA in complex with N-5- formyltetrahydrofolate and UMP | | 分子名称: | ACETATE ION, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, PROTEIN YFBG, ... | | 著者 | Williams, G.J, Breazeale, S.D, Raetz, C.R.H, Naismith, J.H. | | 登録日 | 2005-03-07 | | 公開日 | 2005-04-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure and Function of Both Domains of Arna, a Dual Function Decarboxylase and a Formyltransferase, Involved in 4-Amino-4-Deoxy-L-Arabinose Biosynthesis.
J.Biol.Chem., 280, 2005
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4J6E
 | | Structure of LPXI D225A Mutant | | 分子名称: | (2R,3R,4R,5S,6R)-2-{[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(3R)-3-hydroxytetradecanoyl]amino}tetrahydro-2H-pyran-4-yl (3R)-3-hydroxytetradecanoate, UDP-2,3-diacylglucosamine pyrophosphatase LpxI | | 著者 | Metzger IV, L.E, Lee, J.K, Finer-Moore, J.S, Raetz, C.R.H, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | | 登録日 | 2013-02-11 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | LpxI structures reveal how a lipid A precursor is synthesized.
Nat.Struct.Mol.Biol., 19, 2012
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1LXA
 | | UDP N-ACETYLGLUCOSAMINE ACYLTRANSFERASE | | 分子名称: | UDP N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE | | 著者 | Roderick, S.L. | | 登録日 | 1995-10-07 | | 公開日 | 1995-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase.
Science, 270, 1995
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3I3A
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3I3X
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3B74
 | | Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylethanolamine | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Uncharacterized protein YKL091C | | 著者 | Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V. | | 登録日 | 2007-10-30 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
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3B7N
 | | Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylinositol | | 分子名称: | (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ACETATE ION, PHOSPHATE ION, ... | | 著者 | Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V. | | 登録日 | 2007-10-31 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
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3B7Z
 | | Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylcholine or Phosphatidylinositol | | 分子名称: | (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Uncharacterized protein YKL091C | | 著者 | Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V. | | 登録日 | 2007-10-31 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
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3B7Q
 | | Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylcholine | | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V. | | 登録日 | 2007-10-31 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
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5Y9X
 | | Crystal structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase in complex with alphaketoglutarate and coblat(II) | | 分子名称: | 2-OXOGLUTARIC ACID, ACETATE ION, CHLORIDE ION, ... | | 著者 | Chung, H.S, Pemble, C.W, Joo, S.H, Raetz, C.R. | | 登録日 | 2017-08-29 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Biochemical and structural insights of Fe(II)/alpha-ketoglutarate/O2-dependent dioxygenase, KdoO from Methylacidiphilum infernorum V4
To Be Published
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5Y9Y
 | | Crystal structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase in complex with succinate and Co(II) | | 分子名称: | ACETATE ION, CHLORIDE ION, COBALT (II) ION, ... | | 著者 | Chung, H.S, Pemble, C.W, Joo, S.H, Raetz, C.R. | | 登録日 | 2017-08-29 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Biochemical and structural insights of Fe(II)/alpha-ketoglutarate/O2-dependent dioxygenase, KdoO from Methylacidiphilum infernorum V4
To Be Published
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3P3C
 | | Crystal Structure of the Aquifex aeolicus LpxC/LPC-009 complex | | 分子名称: | N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, PHOSPHATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... | | 著者 | Lee, C.-J, Zhou, P. | | 登録日 | 2010-10-04 | | 公開日 | 2011-01-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
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3P3E
 | | Crystal Structure of the PSEUDOMONAS AERUGINOSA LpxC/LPC-009 complex | | 分子名称: | N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, NITRATE ION, SODIUM ION, ... | | 著者 | Lee, C.-J, Zhou, P. | | 登録日 | 2010-10-04 | | 公開日 | 2011-01-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
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3P3G
 | | Crystal Structure of the Escherichia coli LpxC/LPC-009 complex | | 分子名称: | 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, ... | | 著者 | Lee, C.-J, Zhou, P. | | 登録日 | 2010-10-04 | | 公開日 | 2011-01-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
Chem.Biol., 18, 2011
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3PS1
 | | Crystal structure of the Escherichia Coli LPXC/LPC-011 complex | | 分子名称: | 4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]benzamide, 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, ... | | 著者 | Lee, C.-J, Zhou, P. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.
Bioorg.Med.Chem., 19, 2011
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3PS2
 | | Crystal structure of the Escherichia Coli LPXC/LPC-012 complex | | 分子名称: | 4-[4-(3-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3R)-3-hydroxy-1-nitroso-1-oxobutan-2-yl]benzamide, 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, ... | | 著者 | Lee, C.-J, Zhou, P. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.
Bioorg.Med.Chem., 19, 2011
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3PS3
 | | Crystal structure of the Escherichia Coli LPXC/LPC-053 complex | | 分子名称: | 4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3S)-3-hydroxy-1-nitroso-1-oxobutan-2-yl]benzamide, 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, ... | | 著者 | Lee, C.-J, Zhou, P. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.
Bioorg.Med.Chem., 19, 2011
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6HY2
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8T0J
 | | Salmonella Typhimurium ArnD | | 分子名称: | Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD | | 著者 | Sousa, M.C, Munoz-Escudero, D, Lee, M. | | 登録日 | 2023-06-01 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.
Biochemistry, 62, 2023
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3FID
 | | LpxR from Salmonella typhimurium | | 分子名称: | GLYCEROL, PENTAETHYLENE GLYCOL MONODECYL ETHER, Putative outer membrane protein (LpxR), ... | | 著者 | Rutten, L, Gros, P. | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium
Proc.Natl.Acad.Sci.USA, 106, 2009
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5F42
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6A2E
 | | Apo structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase | | 分子名称: | ACETATE ION, Kdo hydroxylase, KdoO, ... | | 著者 | Chung, H.S, Pemble, C.W, Joo, S.H. | | 登録日 | 2018-06-11 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | | 主引用文献 | Biochemical and Structural Insights into an Fe(II)/ alpha-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO).
J. Mol. Biol., 430, 2018
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