Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylcholine or Phosphatidylinositol

Summary for 3B7Z

Related3B74 3B7N 3B7Q
DescriptorUncharacterized protein YKL091C, (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, ... (4 entities in total)
Functional Keywordssec14, golgi, phospholipid, phosphatidylinositol, phosphatidycholine, signaling protein
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Total number of polymer chains1
Total molecular weight39041.98
Ortlund, E.A.,Schaaf, G.,Redinbo, M.R.,Bankaitis, V. (deposition date: 2007-10-31, release date: 2008-02-19, Last modification date: 2018-02-14)
Primary citation
Schaaf, G.,Ortlund, E.A.,Tyeryar, K.R.,Mousley, C.J.,Ile, K.E.,Garrett, T.A.,Ren, J.,Woolls, M.J.,Raetz, C.R.,Redinbo, M.R.,Bankaitis, V.A.
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29:191-206, 2008
PubMed: 18243114 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2007.11.026
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2308 0.3% 3.2% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28