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4J6E

Structure of LPXI D225A Mutant

Replaces:  4GGI
Summary for 4J6E
Entry DOI10.2210/pdb4j6e/pdb
Related4GGM
DescriptorUDP-2,3-diacylglucosamine pyrophosphatase LpxI, (2R,3R,4R,5S,6R)-2-{[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(3R)-3-hydroxytetradecanoyl]amino}tetrahydro-2H-pyran-4-yl (3R)-3-hydroxytetradecanoate (3 entities in total)
Functional Keywordsstructural genomics, psi-biology, center for structures of membrane proteins, csmp, hydrolase, lipid binding
Biological sourceCaulobacter crescentus
Total number of polymer chains1
Total formula weight30975.77
Authors
Metzger IV, L.E.,Lee, J.K.,Finer-Moore, J.S.,Raetz, C.R.H.,Stroud, R.M.,Center for Structures of Membrane Proteins (CSMP) (deposition date: 2013-02-11, release date: 2013-05-08, Last modification date: 2024-02-28)
Primary citationMetzger IV, L.E.,Lee, J.K.,Finer-Moore, J.S.,Raetz, C.R.H.,Stroud, R.M.
LpxI structures reveal how a lipid A precursor is synthesized.
Nat.Struct.Mol.Biol., 19:1132-1138, 2012
Cited by
PubMed: 23042606
DOI: 10.1038/nsmb.2393
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.52 Å)
Structure validation

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