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2OCP
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BU of 2ocp by Molmil
Crystal Structure of Human Deoxyguanosine Kinase
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxyguanosine kinase
著者Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H.
登録日2006-12-21
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Substrate Specificities of Cellular Deoxyribonucleoside Kinases.
Nat.Struct.Biol., 8, 2001
3RTP
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BU of 3rtp by Molmil
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
分子名称: Mitogen-activated protein kinase 10, N-[4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide
著者Bowers, S, Truong, A.P, Neitz, R.J, Hom, R.K, Sealy, J.M, Probst, G.D, Quincy, Q, Peterson, B, Chan, W, Galemmo Jr, R.A, Konradi, A.W, Sham, H.L, Pan, H, Lin, M, Yao, N, Artis, D.R, Zhang, H, Chen, L, Dryer, M, Samant, B, Zmolek, W, Wong, K, Lorentzen, C, Goldbach, E, Tonn, G, Quinn, K.P, Sauer, J, Wright, S, Powell, K, Ruslim, L, Ren, Z, Bard, F, Yednock, T.A, Griswold-Prenne, I.
登録日2011-05-03
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration.
Bioorg.Med.Chem.Lett., 21, 2011
1RRU
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BU of 1rru by Molmil
The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals
分子名称: Peptide Nucleic Acid, (H-P(*CPN*GPN*TPN*APN*CPN*GPN)-LYS-NH2)
著者Rasmussen, H, Liljefors, T, Petersson, B, Nielsen, P.E, Kastrup, J.S.
登録日2003-12-09
公開日2004-01-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Influence of a Chiral Amino Acid on the Helical Handedness of PNA in Solution and in Crystals
J.Biomol.Struct.Dyn., 21, 2004
2JCS
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BU of 2jcs by Molmil
Active site mutant of dNK from D. melanogaster with dTTP bound
分子名称: DEOXYNUCLEOSIDE KINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
著者Egeblad-Welin, L, Sonntag, Y, Eklund, H, Munch-Petersen, B.
登録日2007-01-03
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional Studies of Active-Site Mutants from Drosophila Melanogaster Deoxyribonucleoside Kinase. Investigations of the Putative Catalytic Glutamate- Arginine Pair and of Residues Responsible for Substrate Specificity.
FEBS J., 274, 2007
2JJ8
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BU of 2jj8 by Molmil
Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase
分子名称: 3'-azido-3'-deoxythymidine, DEOXYNUCLEOSIDE KINASE, SULFATE ION
著者Mikkelsen, N.E, Munch-Petersen, B, Eklund, H.
登録日2008-03-19
公開日2008-04-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
1H0A
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BU of 1h0a by Molmil
Epsin ENTH bound to Ins(1,4,5)P3
分子名称: 1,4-DIETHYLENE DIOXIDE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, EPSIN
著者Ford, M.G.J, McMahon, H.T, Evans, P.R.
登録日2002-06-12
公開日2002-10-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Curvature of Clathrin-Coated Pits Driven by Epsin
Nature, 419, 2002
7PZR
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BU of 7pzr by Molmil
Cryo-EM structure of POLRMT in free form.
分子名称: DNA-directed RNA polymerase, mitochondrial
著者Das, H, Hallberg, B.M.
登録日2021-10-13
公開日2022-11-16
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
7PZP
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BU of 7pzp by Molmil
Mitochondrial DNA dependent RNA polymerase homodimer.
分子名称: DNA-directed RNA polymerase, mitochondrial
著者Das, H, Hallberg, B.M.
登録日2021-10-13
公開日2022-09-28
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
6LUL
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BU of 6lul by Molmil
NMR structure and dynamics studies of yeast respiratory super-complex factor 2 in micelles
分子名称: Respiratory supercomplex factor 2, mitochondrial
著者Zhou, S, Pontus, P, Peter, B, Maler, L, Adelroth, P.
登録日2020-01-29
公開日2020-10-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Structure and Dynamics Studies of Yeast Respiratory Supercomplex Factor 2.
Structure, 29, 2021
6ZDB
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BU of 6zdb by Molmil
NMR structural analysis of yeast Cox13 reveals its C-terminus in interaction with ATP
分子名称: Cytochrome c oxidase subunit 13, mitochondrial
著者Shu, Z, Pontus, P, Peter, B, Lena, M, Pia, A.
登録日2020-06-14
公開日2021-05-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structural analysis of the yeast cytochrome c oxidase subunit Cox13 and its interaction with ATP.
Bmc Biol., 19, 2021
7ZC4
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BU of 7zc4 by Molmil
Cryo-EM structure of POLRMT mutant.
分子名称: DNA-directed RNA polymerase, mitochondrial
著者Das, H, Hallberg, B.M.
登録日2022-03-25
公開日2023-02-01
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
5F9J
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BU of 5f9j by Molmil
Structure of HLA-A2:01 with peptide Y9L
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-12-09
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
5FA3
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BU of 5fa3 by Molmil
Structure of HLA-A2:01 with peptide G9V
分子名称: Beta-2-microglobulin, G9V, GLYCEROL, ...
著者Zajonc, D.M, Remesh, S.G.
登録日2015-12-10
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
6B9J
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BU of 6b9j by Molmil
Structure of vaccinia virus D8 protein bound to human Fab vv138
分子名称: Fab vv138 Heavy chain, Fab vv138 Light chain, GLYCEROL, ...
著者Zajonc, D.M.
登録日2017-10-10
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
4U6H
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BU of 4u6h by Molmil
Vaccinia L1/M12B9-Fab complex
分子名称: Heavy chain of murine anti-vaccinia L1 IgG2a antibody M12B9, Light chain of murine anti-vaccinia L1 IgG2a antibody M12B9, Protein L1
著者Matho, M.H, Schlossman, A, Zajonc, D.M.
登録日2014-07-29
公開日2014-08-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in l1 protein.
J.Virol., 88, 2014
5DDH
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BU of 5ddh by Molmil
Structure of HLA-A2:01 with the 12-mer peptide F12K
分子名称: 12-mer peptide F12K, Beta-2-microglobulin, GLYCEROL, ...
著者Remesh, S.G, Zajonc, D.
登録日2015-08-24
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove.
Elife, 5, 2016
5EOT
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BU of 5eot by Molmil
Structure of HLA-A2:01 with peptide G13E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Zajonc, D.M, Remesh, S.G.
登録日2015-11-10
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
5USH
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BU of 5ush by Molmil
Structure of vaccinia virus D8 protein bound to human Fab vv66
分子名称: Fab vv66 heavy chain, Fab vv66 light chain, IMV membrane protein
著者Zajonc, D.M.
登録日2017-02-13
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
5EOR
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BU of 5eor by Molmil
Structure of the murine antibody Fab 8E3 bound to the vaccinia virus A27 peptide 101-110
分子名称: Protein A27, SODIUM ION, anti vaccinia virus A27 antibody 8E3 heavy chain, ...
著者Matho, M.H, Zajonc, D.M.
登録日2015-11-10
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016
5ENW
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BU of 5enw by Molmil
Structure of HLA-A2:01 with peptide G9L
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-11-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
5EOQ
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BU of 5eoq by Molmil
Structure of the murine Fab 1G6 bound to the vaccinia virus A27 peptide 31-40
分子名称: Anti vaccinia virus A27 antibody Fab 1G6 heavy chain, Anti vaccinia virus A27 antibody Fab 1G6 light chain, Protein A27
著者Matho, M.H, Zajonc, D.M.
登録日2015-11-10
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016
5USL
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BU of 5usl by Molmil
Structure of vaccinia virus D8 protein bound to human Fab vv304
分子名称: Fab vv304 Heavy chain, Fab vv304 Light chain, IMV membrane protein
著者Zajonc, D.M.
登録日2017-02-13
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
J. Biol. Chem., 293, 2018
3UPR
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BU of 3upr by Molmil
HLA-B*57:01 complexed to pep-V and Abacavir
分子名称: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ...
著者Pompeu, Y.A, Ostrov, D.A.
登録日2011-11-18
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proc.Natl.Acad.Sci.USA, 109, 2012
5D9S
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BU of 5d9s by Molmil
Structure of HLA-A2:01 with the 11-mer peptide F11V
分子名称: 11-mer peptide F11V, Beta-2-microglobulin, GLYCEROL, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-08-19
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove.
Elife, 5, 2016
5F7D
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BU of 5f7d by Molmil
Structure of HLA-A2:01 with peptide G11N
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Zajonc, D.M, Remesh, S.G.
登録日2015-12-07
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017

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