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1P00
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BU of 1p00 by Molmil
NMR structure of ETD151, mutant of the antifungal defensin ARD1 from Archaeoprepona demophon
分子名称: defensin ARD1
著者Landon, C, Guenneugues, M, Barbault, F, Legrain, M, Menin, L, Schott, V, Vovelle, F, Dimarcq, J.L.
登録日2003-04-10
公開日2004-03-09
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Lead optimization of antifungal peptides with 3D NMR structures analysis.
Protein Sci., 13, 2004
3QDA
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BU of 3qda by Molmil
Crystal structure of W95L beta-2 microglobulin
分子名称: Beta-2-microglobulin, TRIETHYLENE GLYCOL
著者Ricagno, S, Bellotti, V, Bolognesi, M.
登録日2011-01-18
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
BMC Evol Biol, 11, 2011
1Q3J
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BU of 1q3j by Molmil
Solution structure of ALO3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus
分子名称: ALO3
著者Barbault, F, Landon, C, Guenneugues, M, Meyer, J.P, Schott, V, Dimarrcq, J.L, Vovelle, F.
登録日2003-07-30
公開日2003-12-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus.
Biochemistry, 42, 2003
1KSQ
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BU of 1ksq by Molmil
NMR Study of the Third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1
分子名称: LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 1
著者Lack, J, O'leary, J.M, Knott, V, Yuan, X, Rifkin, D.B, Handford, P.A, Downing, A.K.
登録日2002-01-14
公開日2003-08-26
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly of the Large Latent Complex that Sequesters Latent TGF-beta.
J.Mol.Biol., 334, 2003
2VB5
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BU of 2vb5 by Molmil
Solution structure of W60G mutant of human beta2-microglobulin
分子名称: BETA-2-MICROGLOBULIN
著者Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V.
登録日2007-09-06
公開日2007-09-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties.
J.Mol.Biol., 378, 2008
4DTT
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BU of 4dtt by Molmil
Crystal structure of human insulin degrading enzyme (ide) in complex with compund 41367
分子名称: 2-[[2-[[(2S)-3-(3H-IMIDAZOL-4-YL)-1-METHOXY-1-OXO-PROPAN-2-YL]AMINO]-2-OXO-ETHYL]-(PHENYLMETHYL)AMINO]ETHANOIC ACID, Insulin-degrading enzyme, ZINC ION
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2012-02-21
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Eur.J.Med.Chem., 79, 2014
2G74
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BU of 2g74 by Molmil
Y104F mutant of type 1 isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase
分子名称: Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, MANGANESE (II) ION
著者de Ruyck, J, Wouters, J.
登録日2006-02-27
公開日2006-04-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography.
J.Biol.Chem., 281, 2006
1LYY
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BU of 1lyy by Molmil
AMYLOIDOGENIC VARIANT (ASP67HIS) OF HUMAN LYSOZYME
分子名称: LYSOZYME
著者Sunde, M, Blake, C.C.F.
登録日1997-01-16
公開日1997-04-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis.
Nature, 385, 1997
3IIY
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BU of 3iiy by Molmil
Crystal structure of Eed in complex with a trimethylated histone H1K26 peptide
分子名称: Histone H1K26 peptide, Polycomb protein EED
著者Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J.
登録日2009-08-03
公開日2009-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IIW
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BU of 3iiw by Molmil
Crystal structure of Eed in complex with a trimethylated histone H3K27 peptide
分子名称: Histone H3 peptide, Polycomb protein EED
著者Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J.
登録日2009-08-03
公開日2009-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IJ0
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BU of 3ij0 by Molmil
Crystal structure of Eed in complex with a trimethylated histone H3K9 peptide
分子名称: Histone H3K9 peptide, Polycomb protein EED
著者Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J.
登録日2009-08-03
公開日2009-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IJC
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BU of 3ijc by Molmil
Crystal structure of Eed in complex with NDSB-195
分子名称: ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, Polycomb protein EED
著者Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J.
登録日2009-08-04
公開日2009-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3IJ1
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BU of 3ij1 by Molmil
Crystal structure of Eed in complex with a trimethylated histone H4K20 peptide
分子名称: Histone H4K20 peptide, Polycomb protein EED
著者Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J.
登録日2009-08-03
公開日2009-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
8PWT
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BU of 8pwt by Molmil
Solution structure of the peptide U11-MYRTX-Tb1a from the venom of the ant Tetramorium bicarinatum
分子名称: U11-myrmicitoxin-Tb1a
著者Jouvensal, L, Paquet, F, Loth, K.
登録日2023-07-21
公開日2023-10-25
最終更新日2023-11-08
実験手法SOLUTION NMR
主引用文献Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom.
Toxins, 15, 2023
4WID
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BU of 4wid by Molmil
Crystal structure of the immediate-early 1 protein (IE1) at 2.31 angstrom (tetragonal form after crystal dehydration)
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhUL123
著者Klingl, S, Scherer, M, Sevvana, M, Muller, Y.A, Stamminger, T.
登録日2014-09-25
公開日2014-10-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions.
Plos Pathog., 10, 2014
2YPU
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BU of 2ypu by Molmil
human insulin degrading enzyme E111Q in complex with inhibitor compound 41367
分子名称: 2-[[2-[[(2S)-3-(3H-IMIDAZOL-4-YL)-1-METHOXY-1-OXO-PROPAN-2-YL]AMINO]-2-OXO-ETHYL]-(PHENYLMETHYL)AMINO]ETHANOIC ACID, INSULIN-DEGRADING ENZYME, ZINC ION
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.-J.
登録日2012-11-01
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Imidazole-Derived 2-[N-Carbamoylmethyl-Alkylamino]Acetic Acids,Substrate-Dependent Modulators of Insulin-Degrading Enzyme in Amyloid-Beta Hydrolysis
Eur J Med Chem, 79C, 2014
4GSF
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BU of 4gsf by Molmil
The structure analysis of cysteine free insulin degrading enzyme (ide) with (s)-2-{2-[carboxymethyl-(3-phenyl-propionyl)-amino]-acetylamino}-3-(3h-imidazol-4-yl)-propionic acid methyl ester
分子名称: Insulin-degrading enzyme, ZINC ION, methyl N-(carboxymethyl)-N-(3-phenylpropanoyl)glycyl-D-histidinate
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2012-08-27
公開日2013-08-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.
Eur.J.Med.Chem., 90, 2015
4GS8
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BU of 4gs8 by Molmil
Structure analysis of cysteine free insulin degrading enzyme (ide) with compound bdm43079 [{[(s)-2-(1h-imidazol-4-yl)-1-methylcarbamoyl-ethylcarbamoyl]-methyl}-(3-phenyl-propyl)-amino]-acetic acid
分子名称: Insulin-degrading enzyme, N-(carboxymethyl)-N-(3-phenylpropyl)glycyl-N-methyl-L-histidinamide, ZINC ION
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2012-08-27
公開日2013-08-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Eur.J.Med.Chem., 79, 2014
4GSC
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BU of 4gsc by Molmil
Structure analysis of insulin degrading enzyme with compound bdm41559 ((s)-2-[2-(carboxymethyl-phenethyl-amino)-acetylamino]-3-(1h-imidazol-4-yl)-propionic acid methyl ester)
分子名称: Insulin-degrading enzyme, ZINC ION, methyl N-(carboxymethyl)-N-(2-phenylethyl)glycyl-L-histidinate
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2012-08-27
公開日2013-08-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Eur.J.Med.Chem., 79, 2014
1EMN
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BU of 1emn by Molmil
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
分子名称: CALCIUM ION, FIBRILLIN
著者Downing, A.K, Campbell, I.D, Handford, P.A.
登録日1996-08-05
公開日1996-12-23
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1EMO
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BU of 1emo by Molmil
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES
分子名称: CALCIUM ION, FIBRILLIN
著者Downing, A.K, Campbell, I.D, Handford, P.A.
登録日1996-08-05
公開日1996-12-23
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
4QIA
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BU of 4qia by Molmil
Crystal structure of human insulin degrading enzyme (ide) in complex with inhibitor N-benzyl-N-(carboxymethyl)glycyl-L-histidine
分子名称: Insulin-degrading enzyme, N-benzyl-N-(carboxymethyl)glycyl-L-histidine, ZINC ION
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2014-05-30
公開日2015-05-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.
Eur.J.Med.Chem., 90, 2015
3QZ2
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BU of 3qz2 by Molmil
The structure of cysteine-free human insulin degrading enzyme
分子名称: Insulin-degrading enzyme, ZINC ION
著者Guo, Q, Tang, W.J.
登録日2011-03-04
公開日2012-01-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Eur.J.Med.Chem., 79, 2014
3M1O
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BU of 3m1o by Molmil
Human Transthyretin (TTR) complexed with 2-((3,5-dichloro-4-hydroxyphenyl)amino)benzoic acid
分子名称: 2-[(3,5-dichloro-4-hydroxyphenyl)amino]benzoic acid, Transthyretin
著者Kolstoe, S.E, Wood, S.P.
登録日2010-03-05
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3NA4
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BU of 3na4 by Molmil
D53P beta-2 microglobulin mutant
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin
著者Azinas, S, Ricagno, S, Bolognesi, M.
登録日2010-06-01
公開日2011-06-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献D-strand perturbation and amyloid propensity in beta-2 microglobulin
Febs J., 278, 2011

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