1YT5
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1JFD
| STRUCTURE OF INORGANIC PYROPHOSPHATASE | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | 著者 | Oganesyan, V, Avaeva, S.M, Huber, R, Harutyunyan, E.H. | 登録日 | 1997-05-31 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Escherichia coli inorganic pyrophosphatase complexed with SO4(2-). Ligand-induced molecular asymmetry. FEBS Lett., 410, 1997
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1MJY
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D70N | 分子名称: | INORGANIC PYROPHOSPHATASE | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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1MJW
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D42N | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Samygina, V.R, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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1MJX
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D65N | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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1MJZ
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N | 分子名称: | INORGANIC PYROPHOSPHATASE | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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8TFT
| Fab of O13-1 human IgG1 antibody bound to IgV domain of human TIM-3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, O-13-1 IgG1 Fab heavy chain, O-13-1 IgG1 Fab light chain, ... | 著者 | Oganesyan, V.Y, van Dyk, N, Mazor, Y, Yang, C. | 登録日 | 2023-07-11 | 公開日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Generation of AZD7789, a novel PD-1 and TIM-3 targeting bispecific antibody, which binds to a differentiated epitope of TIM-3 To be published
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5HVW
| Monomeric IgG4 Fc | 分子名称: | GLYCEROL, Ig gamma-4 chain C region, ZINC ION, ... | 著者 | Oganesyan, V.Y, Shan, L, Dall'Acqua, W.F. | 登録日 | 2016-01-28 | 公開日 | 2016-08-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Generation and Characterization of an IgG4 Monomeric Fc Platform. Plos One, 11, 2016
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3SKJ
| Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody | 分子名称: | Antibody, heavy chain, light chain, ... | 著者 | Oganesyan, V.Y, Wu, H, Dall'Acqua, W.F. | 登録日 | 2011-06-22 | 公開日 | 2011-08-31 | 最終更新日 | 2017-05-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody. J.Mol.Biol., 413, 2011
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8TJF
| monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface | 分子名称: | Fab Lambda light chain, IgG1 Fab heavy chain | 著者 | Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C. | 登録日 | 2023-07-21 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023
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8TI4
| monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface | 分子名称: | GLYCEROL, IgG1 Fab heavy chain, mutated to promote correct pairing, ... | 著者 | Oganesyan, V.Y, van Dyk, N, Mazor, Y. | 登録日 | 2023-07-19 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023
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4QXG
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4UB0
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6WIB
| Next generation monomeric IgG4 Fc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION | 著者 | Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N. | 登録日 | 2020-04-09 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
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6WMH
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6WNA
| Next generation monomeric IgG4 Fc | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ... | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | 登録日 | 2020-04-22 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
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6WOL
| Next generation monomeric IgG4 Fc bound to neonatal Fc receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | 登録日 | 2020-04-24 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
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