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1MJZ
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BU of 1mjz by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N
分子名称: INORGANIC PYROPHOSPHATASE
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
1YT5
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BU of 1yt5 by Molmil
Crystal structure of NAD kinase from Thermotoga maritima
分子名称: SULFATE ION, inorganic polyphosphate/ATP-NAD kinase
著者Berkeley Structural Genomics Center (BSGC)
登録日2005-02-09
公開日2005-04-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005
1JFD
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BU of 1jfd by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE
分子名称: INORGANIC PYROPHOSPHATASE, SULFATE ION
著者Oganesyan, V, Avaeva, S.M, Huber, R, Harutyunyan, E.H.
登録日1997-05-31
公開日1997-12-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Escherichia coli inorganic pyrophosphatase complexed with SO4(2-). Ligand-induced molecular asymmetry.
FEBS Lett., 410, 1997
1MJW
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BU of 1mjw by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D42N
分子名称: INORGANIC PYROPHOSPHATASE, SULFATE ION
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Samygina, V.R, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
1MJX
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BU of 1mjx by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D65N
分子名称: INORGANIC PYROPHOSPHATASE, SULFATE ION
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
8TJF
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BU of 8tjf by Molmil
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
分子名称: Fab Lambda light chain, IgG1 Fab heavy chain
著者Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C.
登録日2023-07-21
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
8TI4
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BU of 8ti4 by Molmil
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
分子名称: GLYCEROL, IgG1 Fab heavy chain, mutated to promote correct pairing, ...
著者Oganesyan, V.Y, van Dyk, N, Mazor, Y.
登録日2023-07-19
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
6WIB
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BU of 6wib by Molmil
Next generation monomeric IgG4 Fc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION
著者Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N.
登録日2020-04-09
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WOL
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BU of 6wol by Molmil
Next generation monomeric IgG4 Fc bound to neonatal Fc receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ...
著者Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
登録日2020-04-24
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WNA
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BU of 6wna by Molmil
Next generation monomeric IgG4 Fc
分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ...
著者Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
登録日2020-04-22
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WMH
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BU of 6wmh by Molmil
Next generation monomeric IgG4 Fc
分子名称: Immunoglobulin heavy constant gamma 4
著者Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
登録日2020-04-21
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
4UB0
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BU of 4ub0 by Molmil
New design for monovalent bispecific IgG through cysteine engineering of the CH1-CL interface
分子名称: IgG1, heavy chain, light chain
著者Oganesyan, V.Y, Dall'Acqua, W.F.
登録日2014-08-11
公開日2015-07-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Improving target cell specificity using a novel monovalent bispecific IgG design.
Mabs, 7, 2015
4QXG
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BU of 4qxg by Molmil
Antigen binding fragment of an anti IFNAR1 antibody
分子名称: Fab, heavy chain, IgG1, ...
著者Oganesyan, V.Y, Dall'Acqua, W.F.
登録日2014-07-20
公開日2015-02-25
最終更新日2015-04-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-alpha receptor 1 antibody.
MAbs, 7, 2015
5HVW
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BU of 5hvw by Molmil
Monomeric IgG4 Fc
分子名称: GLYCEROL, Ig gamma-4 chain C region, ZINC ION, ...
著者Oganesyan, V.Y, Shan, L, Dall'Acqua, W.F.
登録日2016-01-28
公開日2016-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Generation and Characterization of an IgG4 Monomeric Fc Platform.
Plos One, 11, 2016
3SKJ
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BU of 3skj by Molmil
Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody
分子名称: Antibody, heavy chain, light chain, ...
著者Oganesyan, V.Y, Wu, H, Dall'Acqua, W.F.
登録日2011-06-22
公開日2011-08-31
最終更新日2017-05-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody.
J.Mol.Biol., 413, 2011
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