8HPK
 
 | | Crystal structure of the bacterial oxalate transporter OxlT in an oxalate-bound occluded form | | 分子名称: | Fab fragment Heavy chein, Fab fragment Light chain, OXALATE ION, ... | | 著者 | Shimamura, T, Hirai, T, Yamashita, A. | | 登録日 | 2022-12-12 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-04-12 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota.
Nat Commun, 14, 2023
|
|
8HPJ
 | |
7KYP
 | |
7KYO
 | |
7P34
 | |
7P1K
 | | Cryo EM structure of bison NHA2 in nano disc structure | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2 | | 著者 | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | | 登録日 | 2021-07-01 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7P1J
 | | Cryo EM structure of bison NHA2 in detergent structure | | 分子名称: | mitochondrial sodium/hydrogen exchanger 9B2 | | 著者 | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | | 登録日 | 2021-07-01 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7P1I
 | | Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix | | 分子名称: | mitochondrial sodium/hydrogen exchanger 9B2 | | 著者 | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | | 登録日 | 2021-07-01 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7VGR
 | |
7VGS
 | |
7W9W
 | | 2.02 angstrom cryo-EM structure of the pump-like channelrhodopsin ChRmine | | 分子名称: | CHOLESTEROL, ChRmine, PALMITIC ACID, ... | | 著者 | Kishi, K.E, Kim, Y, Fukuda, M, Yamashita, K, Deisseroth, K, Kato, H.E. | | 登録日 | 2021-12-11 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine.
Cell, 185, 2022
|
|
7WU9
 | | Cryo-EM structure of the human EP3-Gi signaling complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Suno, R, Sugita, Y, Morimoto, K, Iwasaki, K, Kato, T, Kobayashi, T. | | 登録日 | 2022-02-07 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.375 Å) | | 主引用文献 | Structural insights into the G protein selectivity revealed by the human EP3-G i signaling complex.
Cell Rep, 40, 2022
|
|
5YHL
 | | Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an antagonist Br-derivative | | 分子名称: | 4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl)propanoyl]amino]-4-cyano-phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | | 登録日 | 2017-09-28 | | 公開日 | 2018-12-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
|
|
6AAJ
 | | Crystal structure of JAK2 in complex with peficitinib | | 分子名称: | 4-[[(1S,3R)-5-oxidanyl-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, Tyrosine-protein kinase JAK2 | | 著者 | Amano, Y, Tateishi, Y. | | 登録日 | 2018-07-18 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
Bioorg. Med. Chem., 26, 2018
|
|
6AAH
 | | Crystal structure of JAK1 in complex with peficitinib | | 分子名称: | 4-[[(1S,3R)-5-oxidanyl-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, Tyrosine-protein kinase JAK1 | | 著者 | Amano, Y. | | 登録日 | 2018-07-18 | | 公開日 | 2018-08-15 | | 最終更新日 | 2018-10-24 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
Bioorg. Med. Chem., 26, 2018
|
|
6AAK
 | | Crystal structure of JAK3 in complex with peficitinib | | 分子名称: | 4-[[(1S,3R)-5-oxidanyl-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, Tyrosine-protein kinase JAK3 | | 著者 | Amano, Y. | | 登録日 | 2018-07-18 | | 公開日 | 2018-08-15 | | 最終更新日 | 2018-10-24 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
Bioorg. Med. Chem., 26, 2018
|
|
5YWY
 | | Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208 | | 分子名称: | 4-[4-cyano-2-[[(2R)-2-(4-fluoranylnaphthalen-1-yl)propanoyl]amino]phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | | 登録日 | 2017-11-30 | | 公開日 | 2018-12-05 | | 最終更新日 | 2018-12-19 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
|
|
2WUH
 | | Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide | | 分子名称: | COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2 | | 著者 | Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E. | | 登録日 | 2009-10-05 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2
Structure, 17, 2009
|
|
8J7W
 | | Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
8J7X
 | | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
8J7V
 | | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
8J7U
 | | Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
8J80
 | | Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
8J7T
 | | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
8J7Y
 | | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation | | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | | 著者 | Han, B.B, Inaba, K, Watanabe, S. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
|
|
