7XTX
| High resolution crystal structure of human macrophage migration inhibitory factor in complex with methotrexate | 分子名称: | 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... | 著者 | Sugishima, K, Noguchi, K, Yohda, M, Odaka, M, Matsumura, H. | 登録日 | 2022-05-18 | 公開日 | 2023-05-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Identification of methotrexate as an inhibitor of macrophage migration inhibitory factor by high-resolution crystal structure analysis To Be Published
|
|
5JYM
| |
5JYL
| Human P-cadherin MEC1 with scFv TSP7 bound | 分子名称: | CHLORIDE ION, Cadherin-3, GLYCEROL, ... | 著者 | Caaveiro, J.M.M, Kudo, S, Tsumoto, K. | 登録日 | 2016-05-14 | 公開日 | 2016-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin Sci Rep, 7, 2017
|
|
5I20
| Crystal structure of protein | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, SULFATE ION, Uncharacterized protein | 著者 | Ishitani, R, Nureki, O. | 登録日 | 2016-02-08 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for amino acid export by DMT superfamily transporter YddG. Nature, 534, 2016
|
|
4LZ1
| X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 12 nucleobase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | 著者 | Pica, A, Russo Krauss, I, Merlino, A, Sica, F. | 登録日 | 2013-07-31 | 公開日 | 2014-01-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer. Febs J., 280, 2013
|
|
4LZ4
| X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 3 nucleobase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, ... | 著者 | Pica, A, Russo Krauss, I, Merlino, A, Sica, F. | 登録日 | 2013-07-31 | 公開日 | 2014-01-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer. Febs J., 280, 2013
|
|
8I60
| |
6AF7
| DJ-1 C106S unbound | 分子名称: | CHLORIDE ION, PENTAETHYLENE GLYCOL, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AFI
| DJ-1 with compound 11 | 分子名称: | 1-ethylindole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AF5
| DJ-1 after backsoaking | 分子名称: | CHLORIDE ION, ISATIN, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AFG
| DJ-1 with compound 9 | 分子名称: | 1-methylindole-2,3-dione, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AFH
| DJ-1 with compound 10 | 分子名称: | 1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AFA
| |
6AFE
| DJ-1 with compound 7 | 分子名称: | 7-(trifluoromethyl)-1~{H}-indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AF9
| |
6AFF
| DJ-1 with compound 8 | 分子名称: | CHLORIDE ION, Protein/nucleic acid deglycase DJ-1, methyl 2,3-bis(oxidanylidene)-1~{H}-indole-7-carboxylate | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
6AFJ
| DJ-1 with compound 13 | 分子名称: | CHLORIDE ION, Protein/nucleic acid deglycase DJ-1, butyl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
|
|
8H8N
| Crystal structure of apo-R52Y/E56Y/R59Y/E63Y-rHLFr | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | 著者 | Hishikawa, Y, Noya, H, Maity, B, Abe, S, Ueno, T. | 登録日 | 2022-10-23 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Elucidating Conformational Dynamics and Thermostability of Designed Aromatic Clusters by Using Protein Cages. Chemistry, 29, 2023
|
|
8H8L
| Crystal structure of apo-R52F/E56F/R59F/E63F-rHLFr | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | 著者 | Hishikawa, Y, Noya, H, Maity, B, Abe, S, Ueno, T. | 登録日 | 2022-10-23 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Elucidating Conformational Dynamics and Thermostability of Designed Aromatic Clusters by Using Protein Cages. Chemistry, 29, 2023
|
|
8H8M
| Crystal structure of apo-E53F/E57F/E60F/E64F-rHLFr | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | 著者 | Hishikawa, Y, Noya, H, Maity, B, Abe, S, Ueno, T. | 登録日 | 2022-10-23 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Elucidating Conformational Dynamics and Thermostability of Designed Aromatic Clusters by Using Protein Cages. Chemistry, 29, 2023
|
|
8H8O
| Crystal structure of apo-R52W/E56W/R59W/E63W-rHLFr | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | 著者 | Hishikawa, Y, Noya, H, Maity, B, Abe, S, Ueno, T. | 登録日 | 2022-10-23 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Elucidating Conformational Dynamics and Thermostability of Designed Aromatic Clusters by Using Protein Cages. Chemistry, 29, 2023
|
|
8H63
| Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH10 bound | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K. | 登録日 | 2022-10-15 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes. J.Biol.Chem., 299, 2023
|
|
8H64
| |
8H62
| Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12 | 分子名称: | ACETATE ION, CALCIUM ION, Cadherin-1, ... | 著者 | Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K. | 登録日 | 2022-10-14 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes. J.Biol.Chem., 299, 2023
|
|
5GJ3
| Periplasmic heme-binding protein RhuT from Roseiflexus sp. RS-1 in two-heme bound form (holo-2) | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Periplasmic binding protein, ZINC ION | 著者 | Rahman, M.M, Naoe, Y, Nakamura, N, Shiro, Y, Sugimoto, H. | 登録日 | 2016-06-26 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for binding and transfer of heme in bacterial heme-acquisition systems. Proteins, 85, 2017
|
|