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4AKM
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BU of 4akm by Molmil
Crystal structure of the human lysosome-associated membrane protein LAMP-3 (aka DC-LAMP)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IRIDIUM (III) ION, LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3
著者Krausze, J, Wilke, S, Buessow, K.
登録日2012-02-24
公開日2012-08-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.687 Å)
主引用文献Crystal Structure of the Conserved Domain of the Dc Lysosomal Associated Membrane Protein: Implications for the Lysosomal Glycocalyx.
Bmc Biol., 10, 2012
8RZ6
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BU of 8rz6 by Molmil
SeMet derivative structure of the condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase
分子名称: FORMIC ACID, GLYCEROL, POTASSIUM ION, ...
著者Karanth, M, Schmelz, S, Kirkpatrick, J, Krausze, J, Scrima, A, Carlomagno, T.
登録日2024-02-12
公開日2024-06-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
4UZB
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BU of 4uzb by Molmil
KSHV LANA (ORF73) C-terminal domain mutant bound to LBS1 DNA (R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D)
分子名称: LANA BINDING SITE 1 DNA, ORF 73
著者Hellert, J, Krausze, J, Luhrs, T.
登録日2014-09-05
公開日2015-05-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.865 Å)
主引用文献The 3D Structure of Kaposi Sarcoma Herpesvirus Lana C-Terminal Domain Bound to DNA.
Proc.Natl.Acad.Sci.USA, 112, 2015
8QNF
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BU of 8qnf by Molmil
Crystal structure of the Condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase
分子名称: Condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase, FORMIC ACID, GLYCEROL, ...
著者Karanth, M, Schmelz, S, Kirkpatrick, J, Krausze, J, Scrima, A, Carlomagno, T.
登録日2023-09-26
公開日2024-06-26
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
4UZC
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BU of 4uzc by Molmil
KSHV LANA (ORF73) C-terminal domain, spiral: hexagonal crystal form
分子名称: ORF 73
著者Hellert, J, Krausze, J, Luhrs, T.
登録日2014-09-05
公開日2015-05-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The 3D Structure of Kaposi Sarcoma Herpesvirus Lana C-Terminal Domain Bound to DNA.
Proc.Natl.Acad.Sci.USA, 112, 2015
2YPZ
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BU of 2ypz by Molmil
KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form
分子名称: KSHV LANA
著者Hellert, J, Krausze, J, Luhrs, T.
登録日2012-11-02
公開日2013-11-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献A Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.
Plos Pathog., 9, 2013
2YQ0
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BU of 2yq0 by Molmil
KSHV LANA (ORF73) C-terminal domain, octameric ring: cubic crystal form
分子名称: ORF 73, SULFATE ION
著者Hellert, J, Krausze, J, Luhrs, T.
登録日2012-11-02
公開日2013-11-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.911 Å)
主引用文献A Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.
Plos Pathog., 9, 2013
2YQ1
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BU of 2yq1 by Molmil
MHV-68 LANA (ORF73) C-terminal domain: triclinic crystal form
分子名称: ORF73
著者Hellert, J, Krausze, J, Luhrs, T.
登録日2012-11-02
公開日2013-11-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.
Plos Pathog., 9, 2013
2YPY
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BU of 2ypy by Molmil
KSHV LANA (ORF73) C-terminal domain, decameric ring: monoclinic crystal form
分子名称: CHLORIDE ION, ORF 73
著者Hellert, J, Krausze, J, Luhrs, T.
登録日2012-11-02
公開日2013-11-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.453 Å)
主引用文献A Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.
Plos Pathog., 9, 2013
4D3Z
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BU of 4d3z by Molmil
The structure of inactive prolegumain from chinese hamster, trigonal space group.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROLEGUMAIN
著者Li, W, Heinz, D.W, Krausze, J.
登録日2014-10-24
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
4D3X
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BU of 4d3x by Molmil
The structure of mature legumain from chinese hamster.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN
著者Li, W, Heinz, D.W, Krausze, J.
登録日2014-10-24
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
4D3Y
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BU of 4d3y by Molmil
The structure of inactive prolegumain from chinese hamster.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LEGUMAIN
著者Li, W, Heinz, D.W, Krausze, J.
登録日2014-10-24
公開日2016-01-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
4A4V
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BU of 4a4v by Molmil
Ligand binding domain of human PPAR gamma in complex with amorfrutin 2
分子名称: AMORFRUTIN 2, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者de Groot, J.C, Weidner, C, Krausze, J, Kawamoto, K, Schroeder, F.C, Sauer, S, Buessow, K.
登録日2011-10-20
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor Gamma.
J.Med.Chem., 56, 2013
4A4W
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BU of 4a4w by Molmil
Ligand binding domain of human PPAR gamma in complex with amorfrutin B
分子名称: AMORFRUTIN B, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
著者de Groot, J.C, Weidner, C, Krausze, J, Kawamoto, K, Schroeder, F.C, Sauer, S, Buessow, K.
登録日2011-10-20
公開日2012-10-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor Gamma.
J.Med.Chem., 56, 2013
2YBO
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BU of 2ybo by Molmil
The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH
分子名称: METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE
著者Storbeck, S, Saha, S, Krausze, J, Klink, B.U, Heinz, D.W, Layer, G.
登録日2011-03-08
公開日2011-06-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Heme D1 Biosynthesis Enzyme Nire in Complex with its Substrate Reveals New Insights Into the Catalytic Mechanism of S-Adenosyl-L-Methionine-Dependent Uroporphyrinogen III Methyltransferases.
J.Biol.Chem., 286, 2011
2YBQ
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BU of 2ybq by Molmil
The x-ray structure of the SAM-dependent uroporphyrinogen III methyltransferase NirE from Pseudomonas aeruginosa in complex with SAH and uroporphyrinogen III
分子名称: METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, UROPORPHYRINOGEN III
著者Storbeck, S, Saha, S, Krausze, J, Klink, B.U, Heinz, D.W, Layer, G.
登録日2011-03-09
公開日2011-06-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Heme D1 Biosynthesis Enzyme Nire in Complex with its Substrate Reveals New Insights Into the Catalytic Mechanism of S-Adenosyl-L-Methionine-Dependent Uroporphyrinogen III Methyltransferases.
J.Biol.Chem., 286, 2011
6ZTH
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BU of 6zth by Molmil
Phospholipase PlaB from Legionella pneumophila
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PlaB phospholipase
著者Diwo, M.G, Flieger, A, Blankenfeldt, W.
登録日2020-07-20
公開日2021-06-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZTI
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BU of 6zti by Molmil
Phospholipase PlaB from Legionella pneumophila in complex with thio-NAD
分子名称: GLYCEROL, PlaB phospholipase, THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Diwo, M.G, Flieger, A, Blankenfeldt, W.
登録日2020-07-20
公開日2021-06-02
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB.
Proc.Natl.Acad.Sci.USA, 118, 2021
6R5G
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BU of 6r5g by Molmil
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
分子名称: ITSM, Tyrosine-protein phosphatase non-receptor type 11
著者Marasco, M.
登録日2019-03-25
公開日2020-02-05
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
8QPY
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BU of 8qpy by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase
分子名称: Carrier protein TomAPCP
著者Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
登録日2023-10-03
公開日2024-06-26
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8QRX
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BU of 8qrx by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase in its substrate-loaded state
分子名称: TomAPCP substrate-loaded from the Tomaymycin non-ribosomal peptide synthetase
著者Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
登録日2023-10-09
公開日2024-06-26
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8QSX
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Solution NMR structure of the novel adaptor domain TomBN91 from the Tomaymycin non-ribosomal peptide synthetase
分子名称: TomBN91
著者Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
登録日2023-10-11
公開日2024-06-26
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
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