4UZB

KSHV LANA (ORF73) C-terminal domain mutant bound to LBS1 DNA (R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D)

Summary for 4UZB

• Entry DOI: 10.2210/pdb4uzb/pdb
• Related: 4UZC
• Descriptor: ORF 73, LANA BINDING SITE 1 DNA, ... (4 entities in total)
• Functional Keywords: viral protein-dna complex, dna-binding domain, origin-binding domain, oligomerization domain, hhv-8, gammaherpesvirus, rhadinovirus, primary effusion lymphoma, multicentric castleman's disease, tumor virus, cancer, viral protein/dna
• Biological source: HUMAN HERPESVIRUS 8; More
• Total number of polymer chains: 4
• Total formula weight: 44068.04

Authors

Hellert, J.,Krausze, J.,Luhrs, T. (deposition date: 2014-09-05, release date: 2015-05-13, Last modification date: 2024-01-10)

• Primary citation: Hellert, J.,Weidner-Glunde, M.,Krausze, J.,Lunsdorf, H.,Ritter, C.,Schulz, T.F.,Luhrs, T.; The 3D Structure of Kaposi Sarcoma Herpesvirus Lana C-Terminal Domain Bound to DNA.; Proc.Natl.Acad.Sci.USA, 112:6694-, 2015; PubMed: 25947153; DOI: 10.1073/PNAS.1421804112

Experimental method

X-RAY DIFFRACTION (2.865 Å)