4UZB
KSHV LANA (ORF73) C-terminal domain mutant bound to LBS1 DNA (R1039Q, R1040Q, K1055E, K1109A, D1110A, A1121E, K1138S, K1140D, K1141D)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ORF 73 | polymer | 141 | 15896.1 | 2 | UniProt (Q76SB0) Pfam (PF21501) UniProt (by SIFTS) (Q9QR71) | HUMAN HERPESVIRUS 8 | LATENCY-ASSOCIATED NUCLEAR ANTIGEN, LANA-1, KSHV LANA |
| 2 | C (C) | LANA BINDING SITE 1 DNA | polymer | 20 | 6137.9 | 1 | GenBank (1841835) | HUMAN HERPESVIRUS 8 | |
| 3 | D (D) | LANA BINDING SITE 1 DNA | polymer | 20 | 6137.9 | 1 | GenBank (1841835) | HUMAN HERPESVIRUS 8 | |
| 4 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, B: 1008 - 1146 (UniProt: Q76SB0)
| PDB | External Database | Details |
|---|---|---|
| Gly 1006 | - | expression tag |
| Ser 1007 | - | expression tag |
| Gln 1039 | Arg 1039 | engineered mutation |
| Gln 1040 | Arg 1040 | engineered mutation |
| Glu 1055 | Lys 1055 | engineered mutation |
| Ala 1109 | Lys 1109 | engineered mutation |
| Ala 1110 | Asp 1110 | engineered mutation |
| Glu 1121 | Ala 1121 | engineered mutation |
| Ser 1138 | Lys 1138 | engineered mutation |
| Asp 1140 | Lys 1140 | engineered mutation |
| Asp 1141 | Lys 1141 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44068.0 | |
| All* | Total formula weight | 44068.0 |
