2YPZ

KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form

Summary for 2YPZ

• Entry DOI: 10.2210/pdb2ypz/pdb
• Related: 2YPY 2YQ0 2YQ1
• Descriptor: KSHV LANA (1 entity in total)
• Functional Keywords: viral protein, latency-associated nuclear antigen, lana-1, dna-binding domain, origin-binding domain, oligomerization domain, kaposi's sarcoma-associated herpesvirus, gammaherpesvirus, rhadinovirus, primary effusion lymphoma, multicentric castleman's disease, tumor virus, cancer, murid herpesvirus 4, muhv-4, murid herpesvirus 68, mhv-68
• Biological source: HUMAN HERPESVIRUS 8 TYPE M
• Total number of polymer chains: 10
• Total formula weight: 157602.01

Authors

Hellert, J.,Krausze, J.,Luhrs, T. (deposition date: 2012-11-02, release date: 2013-11-13, Last modification date: 2023-12-20)

• Primary citation: Hellert, J.,Weidner-Glunde, M.,Krausze, J.,Richter, U.,Adler, H.,Fedorov, R.,Pietrek, M.,Ruckert, J.,Ritter, C.,Schulz, T.F.,Luhrs, T.; A Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.; Plos Pathog., 9:3640-, 2013; PubMed: 24146614; DOI: 10.1371/JOURNAL.PPAT.1003640

Experimental method

X-RAY DIFFRACTION (3.199 Å)