4JQI
| Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide | 分子名称: | 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ... | 著者 | Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J. | 登録日 | 2013-03-20 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature, 497, 2013
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5G15
| Structure Aurora A (122-403) bound to activating monobody Mb1 and AMPPCP | 分子名称: | AURORA A KINASE, MAGNESIUM ION, MB1 MONOBODY, ... | 著者 | Zorba, A, Kutter, S, Kern, D, Koide, S, Koide, A. | 登録日 | 2016-03-23 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Allosteric modulation of a human protein kinase with monobodies. Proc.Natl.Acad.Sci.USA, 116, 2019
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7JW7
| Structure of monobody 27 human MLKL pseudokinase domain complex | 分子名称: | Mixed lineage kinase domain-like protein, Monobody 27 | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | 登録日 | 2020-08-25 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nat Commun, 12, 2021
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7JXU
| Structure of monobody 32 human MLKL pseudokinase domain complex | 分子名称: | 1,2-ETHANEDIOL, Mixed lineage kinase domain-like protein, Monobody 32 | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | 登録日 | 2020-08-28 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis. Nat Commun, 12, 2021
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7KZZ
| Cryo-EM structure of YiiP-Fab complex in Holo state | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ... | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | 登録日 | 2020-12-10 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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7KZX
| Cryo-EM structure of YiiP-Fab complex in Apo state | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | 登録日 | 2020-12-10 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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6WW5
| Structure of VcINDY-Na-Fab84 in nanodisc | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DASS family sodium-coupled anion symporter, Fab84 Heavy Chain, ... | 著者 | Sauer, D.B, Marden, J, Song, J.M, Koide, A, Koide, S, Wang, D.N. | 登録日 | 2020-05-07 | 公開日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural basis for the reaction cycle of DASS dicarboxylate transporters. Elife, 9, 2020
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3EC5
| The crystal structure of Thioflavin-T (ThT) binding OspA mutant | 分子名称: | Outer Surface Protein A, TETRAETHYLENE GLYCOL | 著者 | Biancalana, M, Makabe, K, Koide, A, Koide, S. | 登録日 | 2008-08-28 | 公開日 | 2009-02-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies J.Mol.Biol., 385, 2009
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5DC9
| CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL B | 分子名称: | AS25 monobody, GLYCEROL, IMIDAZOLE, ... | 著者 | Wojcik, J.B, Koide, A, Koide, S. | 登録日 | 2015-08-23 | 公開日 | 2016-03-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface. J.Biol.Chem., 291, 2016
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3CH8
| The crystal structure of PDZ-Fibronectin fusion protein | 分子名称: | C-terminal octapeptide from protein ARVCF, MAGNESIUM ION, fusion protein PDZ-Fibronectin,Fibronectin | 著者 | Makabe, K, Huang, J, Koide, A, Koide, S. | 登録日 | 2008-03-08 | 公開日 | 2009-03-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution. J.Mol.Biol., 392, 2009
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5DC4
| CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL A | 分子名称: | AS25 monobody, GLYCEROL, Tyrosine-protein kinase ABL1 | 著者 | Wojcik, J.B, Koide, A, Koide, S. | 登録日 | 2015-08-23 | 公開日 | 2016-03-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface. J.Biol.Chem., 291, 2016
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6D0N
| Crystal structure of a CLC-type fluoride/proton antiporter, V319G mutant | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | 登録日 | 2018-04-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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6D0K
| Crystal structure of a CLC-type fluoride/proton antiporter, E118Q mutant | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | 登録日 | 2018-04-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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6D0J
| Crystal structure of a CLC-type fluoride/proton antiporter | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | 登録日 | 2018-04-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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2P42
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE3-mono-2 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold | 分子名称: | ANTIBODY CAB-RN05, MAGNESIUM ION, Ribonuclease pancreatic | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P48
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.3A resolution: SE5B-tetra crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P45
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.1A resolution: SE5B-ORTHO-1 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P47
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: SE5B-TRI crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P44
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE5A-mono-1 crystal form with five se-met sites (M34, M51, F68M, M83, L86M) in vhh scaffold | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P43
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.65A resolution: SE3-mono-1 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P46
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: se5b-ortho-2 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic, ZINC ION | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2OY8
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2OY7
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3RZW
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2OBG
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