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5J88
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BU of 5j88 by Molmil
Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-07
公開日2016-07-06
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J5B
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BU of 5j5b by Molmil
Structure of the WT E coli ribosome bound to tetracycline
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-01
公開日2016-07-27
最終更新日2018-08-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IT8
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BU of 5it8 by Molmil
High-resolution structure of the Escherichia coli ribosome
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-03-16
公開日2016-07-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J8A
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BU of 5j8a by Molmil
Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-07
公開日2016-07-06
最終更新日2016-08-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JC9
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BU of 5jc9 by Molmil
Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-14
公開日2016-07-06
最終更新日2016-08-03
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J7L
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BU of 5j7l by Molmil
Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Cocozaki, A, Ferguson, A.
登録日2016-04-06
公開日2016-07-27
最終更新日2018-08-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
3GLG
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BU of 3glg by Molmil
Crystal Structure of a Mutant (gammaT157A) E. coli Clamp Loader Bound to Primer-Template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
著者Simonetta, K.R, Seyedin, S.N, Kuriyan, J.
登録日2009-03-12
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
3GLF
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BU of 3glf by Molmil
Crystal Structure of the Ecoli Clamp Loader Bound to Primer-Template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
著者Simonetta, K.R, Kuriyan, J.
登録日2009-03-12
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.388 Å)
主引用文献The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
3GLI
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BU of 3gli by Molmil
Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(*CP*TP*GP*GP*CP*CP*TP*AP*TP*A)-3'), ...
著者Simonetta, K.R, Cantor, A.J, Kuriyan, J.
登録日2009-03-12
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
Cell(Cambridge,Mass.), 137, 2009
4Z8D
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BU of 4z8d by Molmil
Antibacterial FabH Inhibitors with Validated Mode of Action in Haemophilus Influenzae by in vitro resistance mutation mapping
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, SULFATE ION, trans-4-[({[(2-chlorobenzyl)oxy]carbonyl}amino)methyl]cyclohexanecarboxylic acid
著者Lahiri, S.D.
登録日2015-04-08
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping.
Acs Infect Dis., 2, 2016
6QB6
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BU of 6qb6 by Molmil
Mcl1 in complex with a Fab
分子名称: Fab Heavy Chain, Fab Light Chain, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Hargreaves, D.
登録日2018-12-20
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QB4
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BU of 6qb4 by Molmil
Mcl1-scFv complex with an indole acid inhibitor
分子名称: 3-[3-[[(1~{R})-1,2,3,4-tetrahydronaphthalen-1-yl]oxy]propyl]-7-(1,3,5-trimethylpyrazol-4-yl)-1~{H}-indole-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55
著者Hargreaves, D.
登録日2018-12-20
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QB9
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BU of 6qb9 by Molmil
Structure of an anti-Mcl1 scFv
分子名称: L(+)-TARTARIC ACID, scFv55
著者Hargreaves, D.
登録日2018-12-20
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QBC
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BU of 6qbc by Molmil
structure of anti-Mcl1 Fab
分子名称: Anti-Mcl1 Fab Heavy Chain, Anti-Mcl1 Fab Light Chain
著者Luptak, J.
登録日2018-12-20
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QF9
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BU of 6qf9 by Molmil
Structure of an anti-Mcl1 scFv
分子名称: scFv
著者Luptak, J.
登録日2019-01-09
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QFC
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BU of 6qfc by Molmil
Structure of an anti-Mcl1 scFv
分子名称: DIMETHYL SULFOXIDE, Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55
著者Luptak, J.
登録日2019-01-09
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
1EM8
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BU of 1em8 by Molmil
Crystal structure of chi and psi subunit heterodimer from DNA POL III
分子名称: DNA POLYMERASE III CHI SUBUNIT, DNA POLYMERASE III PSI SUBUNIT
著者Gulbis, J.M, Finkelstein, J, O'Donnell, M, Kuriyan, J.
登録日2000-03-16
公開日2003-08-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the chi:psi sub-assembly of the Escherichia coli DNA polymerase clamp-loader complex.
Eur.J.Biochem., 271, 2004
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