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2WXC
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BU of 2wxc by Molmil
The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family.
分子名称: DIHYDROLIPOYLTRANSSUCCINASE
著者Neuweiler, H, Sharpe, T.D, Rutherford, T.J, Johnson, C.M, Allen, M.D, Ferguson, N, Fersht, A.R.
登録日2009-11-06
公開日2009-11-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Folding Mechanism of Bbl: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family.
J.Mol.Biol., 390, 2009
1W4H
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BU of 1w4h by Molmil
Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE
著者Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R.
登録日2004-07-23
公開日2005-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
1W4E
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BU of 1w4e by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE
著者Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R.
登録日2004-07-23
公開日2005-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
1W4K
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BU of 1w4k by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: PYRUVATE DEHYDROGENASE E2
著者Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R.
登録日2004-07-23
公開日2005-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
1W4I
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BU of 1w4i by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: PYRUVATE DEHYDROGENASE E2
著者Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R.
登録日2004-07-23
公開日2005-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
2J2S
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BU of 2j2s by Molmil
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase
分子名称: ZINC FINGER PROTEIN HRX, ZINC ION
著者Allen, M.D, Grummitt, C.G, Hilcenko, C, Young-Min, S, Tonkin, L.M, Johnson, C.M, Bycroft, M, Warren, A.J.
登録日2006-08-17
公開日2006-08-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Nonmethyl-Cpg-Binding Cxxc Domain of the Leukaemia-Associated Mll Histone Methyltransferase
Embo J., 25, 2006
6QJY
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BU of 6qjy by Molmil
Solution NMR structure of a mutant major ampullate spidroin 1 N-terminal domain
分子名称: Major ampullate spidroin 1
著者Goretzki, B, Heiby, J, Neuweiler, H, Hellmich, U.A.
登録日2019-01-27
公開日2019-09-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution NMR structure of a mutant major ampullate spidroin 1 N-terminal domain
Nat Commun, 2019
2Y3W
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BU of 2y3w by Molmil
N-terminal head domain and beginning of coiled coil domain of Danio rerio SAS-6
分子名称: SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG
著者van Breugel, M.
登録日2010-12-27
公開日2011-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of SAS-6 suggest its organization in centrioles.
Science, 331, 2011
5IHB
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BU of 5ihb by Molmil
Structure of the immune receptor CD33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33
著者Dodd, R.B.
登録日2016-02-29
公開日2017-03-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure of ligand bound CD33 receptor associated with Alzheimer's disease
To Be Published
5J0B
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BU of 5j0b by Molmil
Structure of the immune receptor CD33 in complex with 6'-sialyllactose
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ...
著者Dodd, R.B.
登録日2016-03-28
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
To Be Published
5J06
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BU of 5j06 by Molmil
Structure of the immune receptor CD33 in complex with 3'-sialyllactose
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ...
著者Dodd, R.B.
登録日2016-03-27
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
To Be Published
5KC2
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BU of 5kc2 by Molmil
Negative stain structure of Vps15/Vps34 complex
分子名称: Phosphatidylinositol 3-kinase VPS34, Serine/threonine-protein kinase VPS15
著者Kirsten, M.L, Zhang, L, Ohashi, Y, Perisic, O, Williams, R.L, Sachse, C.
登録日2016-06-04
公開日2016-10-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (28 Å)
主引用文献Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex.
Autophagy, 12, 2016
6HXY
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BU of 6hxy by Molmil
Crystal structure of the head and coiled-coil domains of zebrafish CCDC61
分子名称: Coiled-coil domain-containing protein 61
著者Ochi, T, van Breugel, M.
登録日2018-10-18
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020
6HXV
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BU of 6hxv by Molmil
Crystal structure of the head and coiled-coil domains of zebrafish CCDC61 (F129E/D130A)
分子名称: Coiled-coil domain-containing protein 61
著者Barnabas, D, Ochi, T, van Breugel, M.
登録日2018-10-18
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020
6HXT
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BU of 6hxt by Molmil
Crystal structure of the head domain of human CCDC61
分子名称: Coiled-coil domain-containing protein 61
著者Ochi, T, Blundell, T.L, van Breugel, M.
登録日2018-10-18
公開日2020-04-29
最終更新日2020-06-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020
4WIP
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BU of 4wip by Molmil
DIX domain of human Dvl2
分子名称: PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2
著者Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W.
登録日2014-09-26
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Nat Commun, 6, 2015
4WZP
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BU of 4wzp by Molmil
Ser65 phosphorylated ubiquitin, major conformation
分子名称: SULFATE ION, ubiquitin
著者Wauer, T, Wagstaff, J, Freund, S.M.V, Komander, D.
登録日2014-11-20
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
Embo J., 34, 2015
5LNP
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BU of 5lnp by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-05
公開日2016-10-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
5LPH
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BU of 5lph by Molmil
Structure of the TOG domain of human Cep104
分子名称: Centrosomal protein of 104 kDa
著者van Breugel, M.
登録日2016-08-13
公開日2017-01-11
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
5LPI
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BU of 5lpi by Molmil
Structure of the zinc finger array of Cep104
分子名称: Centrosomal protein of 104 kDa, ZINC ION
著者van Breugel, M, Yu, M, al Jassar, C.
登録日2016-08-13
公開日2017-01-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
6S6A
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BU of 6s6a by Molmil
Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L.
登録日2019-07-02
公開日2019-10-16
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
6SB2
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BU of 6sb2 by Molmil
cryo-EM structure of mTORC1 bound to active RagA/C GTPases
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ...
著者Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L.
登録日2019-07-18
公開日2019-10-16
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
6SB0
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BU of 6sb0 by Molmil
cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Proline-rich AKT1 substrate 1, ...
著者Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L.
登録日2019-07-18
公開日2019-10-16
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
6S6D
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BU of 6s6d by Molmil
Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L.
登録日2019-07-02
公開日2019-10-16
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
4BXP
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BU of 4bxp by Molmil
Structure of the wild-type TCP10 domain of Danio rerio CPAP
分子名称: CPAP
著者van Breugel, M.
登録日2013-07-15
公開日2013-09-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
Elife, 2, 2013

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