2R02
| |
4WLP
| Crystal structure of UCH37-NFRKB Inhibited Deubiquitylating Complex | 分子名称: | Nuclear factor related to kappa-B-binding protein, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
|
|
4WNN
| SPT16-H2A-H2B FACT HISTONE Complex | 分子名称: | Histone H2A.1, Histone H2B.1, PHOSPHATE ION, ... | 著者 | Kemble, D.J, Hill, C.P, Whitby, F.G, Formosa, T, McCullough, L.L. | 登録日 | 2014-10-13 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol.Cell, 60, 2015
|
|
4WLQ
| Crystal structure of mUCH37-hRPN13 CTD complex | 分子名称: | Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
|
|
1CMX
| |
3DFZ
| SirC, precorrin-2 dehydrogenase | 分子名称: | GLYCEROL, Precorrin-2 dehydrogenase, SULFATE ION | 著者 | Schubert, H.L, Hill, C.P, Warren, M.J. | 登録日 | 2008-06-12 | 公開日 | 2008-10-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and function of SirC from Bacillus megaterium: a metal-binding precorrin-2 dehydrogenase Biochem.J., 415, 2008
|
|
1JPH
| Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
|
|
1JPI
| Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
|
|
1JPK
| Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
|
|
4WLR
| Crystal Structure of mUCH37-hRPN13 CTD-hUb complex | 分子名称: | Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
|
|
1TLB
| Yeast coproporphyrinogen oxidase | 分子名称: | Coproporphyrinogen III oxidase, SULFATE ION | 著者 | Phillip, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | 登録日 | 2004-06-09 | 公開日 | 2004-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the oxygen-dependent coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
|
|
1URO
| UROPORPHYRINOGEN DECARBOXYLASE | 分子名称: | BETA-MERCAPTOETHANOL, PROTEIN (UROPORPHYRINOGEN DECARBOXYLASE) | 著者 | Whitby, F.G, Phillips, J.D, Kushner, J.P, Hill, C.P. | 登録日 | 1998-08-21 | 公開日 | 1998-08-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human uroporphyrinogen decarboxylase. EMBO J., 17, 1998
|
|
1TK1
| YEAST OXYGEN-DEPENDENT COPROPORPHYRINOGEN OXIDASE | 分子名称: | Coproporphyrinogen III oxidase | 著者 | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | 登録日 | 2004-06-08 | 公開日 | 2004-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
|
|
1TKL
| Yeast Oxygen-Dependent Coproporphyrinogen Oxidase | 分子名称: | Coproporphyrinogen III oxidase | 著者 | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | 登録日 | 2004-06-08 | 公開日 | 2004-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
|
|
6OMB
| Cdc48 Hexamer (Subunits A to E) with substrate bound to the central pore | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. | 登録日 | 2019-04-18 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
|
|
6OPC
| Cdc48 Hexamer in a complex with substrate and Shp1(Ubx Domain) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. | 登録日 | 2019-04-24 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
|
|
6OO2
| Vps4 with Cyclic Peptide Bound in the Central Pore | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Designed Cyclic Peptide, ... | 著者 | Han, H, Fulcher, J.M, Dandey, V.P, Sundquist, W.I, Kay, M.S, Shen, P, Hill, C.P. | 登録日 | 2019-04-22 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases. Elife, 8, 2019
|
|
6OI4
| RPN13 (19-132)-RPN2 (940-952) pY950-Ub complex | 分子名称: | 1,2-ETHANEDIOL, 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, ... | 著者 | Hemmis, C.W, Hill, C.P. | 登録日 | 2019-04-08 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Phosphorylation of Tyr-950 in the proteasome scaffolding protein RPN2 modulates its interaction with the ubiquitin receptor RPN13. J.Biol.Chem., 294, 2019
|
|
6PEK
| Structure of Spastin Hexamer (Subunit A-E) in complex with substrate peptide | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P. | 登録日 | 2019-06-20 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. J.Biol.Chem., 295, 2020
|
|
6PEN
| Structure of Spastin Hexamer (whole model) in complex with substrate peptide | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, EYEYEYEYEY, ... | 著者 | Han, H, Schubert, H.L, McCullough, J, Monroe, N, Sundquist, W.I, Hill, C.P. | 登録日 | 2019-06-20 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. J.Biol.Chem., 295, 2020
|
|
6NDY
| Vps4 with Cyclic Peptide Bound in the Central Pore | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Designed Cyclic Peptide, ... | 著者 | Han, H, Fulcher, J.M, Dandey, V.P, Sundquist, W.I, Kay, M.S, Shen, P, Hill, C.P. | 登録日 | 2018-12-14 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases. Elife, 8, 2019
|
|
3ZXP
| |
8UC6
| Calpain-7:IST1 Complex | 分子名称: | Calpain-7, IST1 homolog | 著者 | Paine, E, Whitby, F.G, Hill, C.P, Sunquist, W.I. | 登録日 | 2023-09-25 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission. Elife, 12, 2023
|
|
8V14
| Structure of NRAP-1 and its role in NMDAR signaling | 分子名称: | CALCIUM ION, NMDA receptor auxiliary protein | 著者 | Whitby, F.G, Goodell, D.J, Maricq, A.V, Hill, C.P. | 登録日 | 2023-11-19 | 公開日 | 2024-01-31 | 最終更新日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic and structural studies reveal NRAP-1-dependent coincident activation of NMDARs. Cell Rep, 43, 2024
|
|
7SMU
| Crystal Structure of Consomatin-Ro1 | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaoctatetracontane-1,48-diol, Consomatin-Ro1 | 著者 | Ramiro, I.B.L, Whitby, F.G, Hill, C.P, Safavi-Hemami, H, Concepcion, G.P, Olivera, B.M. | 登録日 | 2021-10-26 | 公開日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads. Sci Adv, 8, 2022
|
|