2NO6
 
 | | C4S dCK variant of dCK in complex with FTC+ADP | | 分子名称: | 4-AMINO-5-FLUORO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | | 著者 | Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A. | | 登録日 | 2006-10-25 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
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2ZI5
 | | C4S dCK variant of dCK in complex with L-dA+UDP | | 分子名称: | (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
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2ZI3
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2ZI4
 | | C4S dCK variant of dCK in complex with L-dA+ADP | | 分子名称: | (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ... | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
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2ZI6
 | | C4S dCK variant of dCK in complex with D-dA+UDP | | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
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2NO9
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2NOA
 | | The structure of deoxycytidine kinase complexed with lamivudine and ADP. | | 分子名称: | 4-AMINO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2006-10-25 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.
Nucleic Acids Res., 35, 2007
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2ZIA
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2ZI9
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2ZI7
 | | C4S dCK variant of dCK in complex with D-dG+UDP | | 分子名称: | 2'-DEOXY-GUANOSINE, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase
J.Med.Chem., 51, 2008
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