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133D
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BU of 133d by Molmil
THE CRYSTAL STRUCTURE OF N4-METHYLCYTOSINE.GUANOSIN BASE-PAIRS IN THE SYNTHETIC HEXANUCLEOTIDE D(CGCGM(4)CG)
分子名称: DNA (5'-D(*CP*GP*CP*GP*(C34)P*G)-3')
著者Cervi, A.R, Guy, A, Leonard, G.A, Teoule, R, Hunter, W.N.
登録日1993-07-29
公開日1994-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of N4-methylcytosine.guanosine base-pairs in the synthetic hexanucleotide d(CGCGm4CG).
Nucleic Acids Res., 21, 1993
1D75
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BU of 1d75 by Molmil
CONFORMATION OF THE GUANINE.8-OXOADENINE BASE PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(O8A)GCG)
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(A38)P*GP*CP*G)-3')
著者Leonard, G.A, Guy, A, Brown, T, Teoule, R, Hunter, W.N.
登録日1992-05-07
公開日1993-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Biochemistry, 31, 1992
9CKV
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BU of 9ckv by Molmil
Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Werther, R, Nguyen, A, Estrada Alamo, K.A, Wang, X, Campbell, M.G.
登録日2024-07-09
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献De Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine
To Be Published
1BEI
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BU of 1bei by Molmil
Shk-dnp22: A Potent Kv1.3-specific immunosuppressive polypeptide, NMR, 20 structures
分子名称: POTASSIUM CHANNEL TOXIN SHK
著者Kalman, K, Pennington, M.W, Lanigan, M.D, Nguyen, A, Rauer, H, Mahnir, V, Gutman, G.A, Paschetto, K, Kem, W.R, Grissmer, S, Christian, E.P, Cahalan, M.D, Norton, R.S, Chandy, K.G.
登録日1998-05-14
公開日1998-12-02
最終更新日2022-12-21
実験手法SOLUTION NMR
主引用文献ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
J.Biol.Chem., 273, 1998
2C1J
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BU of 2c1j by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-15
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
2C1N
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BU of 2c1n by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-16
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
7APL
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tRNA-guanine transglycosylase G87C mutant spin-labeled with MTSL
分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION
著者Nguyen, D, Heine, A, Klebe, G.
登録日2020-10-18
公開日2020-10-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Unraveling a Ligand-Induced Twist of a Homodimeric Enzyme by Pulsed Electron-Electron Double Resonance.
Angew.Chem.Int.Ed.Engl., 60, 2021
7APM
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BU of 7apm by Molmil
tRNA-guanine transglycosylase H319C mutant spin-labeled with MTSL.
分子名称: CHLORIDE ION, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
著者Nguyen, D, Heine, A, Klebe, G.
登録日2020-10-18
公開日2020-10-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Unraveling a Ligand-Induced Twist of a Homodimeric Enzyme by Pulsed Electron-Electron Double Resonance.
Angew.Chem.Int.Ed.Engl., 60, 2021
4RP7
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BU of 4rp7 by Molmil
Structure of the amyloid-forming segment TIITLE from p53 (residues 253-258)
分子名称: TIITLE hexapeptide segment from p53, ZINC ION
著者Soriaga, A.B, Soragni, A, Eisenberg, D.
登録日2014-10-29
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4RP6
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BU of 4rp6 by Molmil
Structure of the amyloid-forming segment LTIITLE from p53 (residues 252-258)
分子名称: LTIITLE heptapeptide segment from p53
著者Soriaga, A.B, Soragni, A, Eisenberg, D.
登録日2014-10-29
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
7JH5
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BU of 7jh5 by Molmil
Co-LOCKR: de novo designed protein switch
分子名称: Co-LOCKR: de novo designed protein switch
著者Bick, M.J, Lajoie, M.J, Boyken, S.E, Sankaran, B, Baker, D.
登録日2020-07-20
公開日2020-09-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Designed protein logic to target cells with precise combinations of surface antigens.
Science, 369, 2020
6X00
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BU of 6x00 by Molmil
Structure of DbNA(11) peptides bound to H-2Db MHC-I
分子名称: Beta-2-microglobulin, Epitope from Neuraminidase Protein (NA-181-191), H-2 class I histocompatibility antigen, ...
著者Farenc, C, Rossjohn, J.
登録日2020-05-14
公開日2020-09-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Overlapping Peptides Elicit Distinct CD8 + T Cell Responses following Influenza A Virus Infection.
J Immunol., 205, 2020
6WZY
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BU of 6wzy by Molmil
Structure of DbNA(10) peptides bound to H-2Db MHC-I
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Farenc, C, Rossjohn, J.
登録日2020-05-14
公開日2020-09-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Overlapping Peptides Elicit Distinct CD8 + T Cell Responses following Influenza A Virus Infection.
J Immunol., 205, 2020
8AYH
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BU of 8ayh by Molmil
Structure of Complement C5 in Complex with small molecule inhibitor and CVF
分子名称: 5-methoxy-2-[[(1~{S})-1-(2-methoxyphenyl)ethyl]carbamoylamino]-4-(4-methylpentoxy)benzoic acid, Cobra venom factor, Complement C5 alpha chain, ...
著者Srinivas, H.
登録日2022-09-02
公開日2022-12-21
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献A small-molecule inhibitor of C5 complement protein.
Nat.Chem.Biol., 15, 2019
8AXW
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BU of 8axw by Molmil
The structure of mouse AsterC (GramD1c) with Ezetimibe
分子名称: (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, CHLORIDE ION, ETHANOL, ...
著者Fairall, L, Xiao, X, Burger, L, Tontonoz, P, Schwabe, J.W.R.
登録日2022-09-01
公開日2023-09-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Science, 382, 2023
7UV9
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BU of 7uv9 by Molmil
KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate
分子名称: DNA (185-MER), FE (III) ION, Histone H2A type 1, ...
著者Spangler, C.J, Skrajna, A, Foley, C.A, Budziszewski, G.R, Azzam, D.N, James, L.I, Frye, S.V, McGinty, R.K.
登録日2022-04-29
公開日2023-02-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
7UVA
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BU of 7uva by Molmil
Crystal structure of KDM2A histone demethylase catalytic domain in complex with an H3C36 peptide modified by UNC8015
分子名称: FE (III) ION, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Budziszewski, G.R, Azzam, D.N, Spangler, C.J, Skrajna, A, Foley, C.A, James, L.I, Frye, S.V, McGinty, R.K.
登録日2022-04-29
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
3KHQ
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BU of 3khq by Molmil
Crystal structure of murine Ig-beta (CD79b) in the monomeric form
分子名称: B-cell antigen receptor complex-associated protein beta chain, CITRATE ANION, GLUTATHIONE, ...
著者Radaev, S, Sun, P.D.
登録日2009-10-30
公開日2010-08-25
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3KG5
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BU of 3kg5 by Molmil
Crystal structure of human Ig-beta homodimer
分子名称: B-cell antigen receptor complex-associated protein beta chain
著者Radaev, S, Sun, P.D.
登録日2009-10-28
公開日2010-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3KHO
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BU of 3kho by Molmil
Crystal structure of murine Ig-beta (CD79b) homodimer
分子名称: B-cell antigen receptor complex-associated protein beta chain, SULFATE ION
著者Radaev, S, Sun, P.D.
登録日2009-10-30
公開日2010-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3HR5
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BU of 3hr5 by Molmil
M1prime peptide from IgE bound by humanized antibody 47H4 Fab
分子名称: Fab h47H4 heavy chain, Fab h47H4 light chain, GLYCEROL, ...
著者Eigenbrot, C.W, Ultsch, M.H.
登録日2009-06-08
公開日2010-05-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.
J.Clin.Invest., 120, 2010
7JWI
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BU of 7jwi by Molmil
Crystal structure of B17.R2 TCR in complex with H2D-b-NP366
分子名称: 1,2-ETHANEDIOL, B17.R2 TCR alpha chain, B17.R2 TCR beta chain, ...
著者Farenc, C, Rossjohn, J.
登録日2020-08-25
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Science, 372, 2021
7JWJ
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BU of 7jwj by Molmil
Crystal Structure of B17-C1 TCR-H2Db
分子名称: B17.C1 TCR alpha chain, B17.C1 TCR beta chain, Beta-2-microglobulin, ...
著者Farenc, C, Rossjohn, J, Gras, S, Szeto, C.
登録日2020-08-25
公開日2021-07-07
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.251 Å)
主引用文献Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Science, 372, 2021
3UIE
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BU of 3uie by Molmil
Crystal structure of adenosine 5'-phosphosulfate kinase from Arabidopsis Thaliana in Complex with AMPPNP and APS
分子名称: ADENOSINE-5'-PHOSPHOSULFATE, Adenylyl-sulfate kinase 1, chloroplastic, ...
著者Ravilious, G.E, Jez, J.M.
登録日2011-11-04
公開日2012-01-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献Structural basis and evolution of redox regulation in plant adenosine-5'-phosphosulfate kinase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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