Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3IW4
DownloadVisualize
BU of 3iw4 by Molmil
Crystal structure of PKC alpha in complex with NVP-AEB071
分子名称: 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione, Protein kinase C alpha type
著者Stark, W, Rummel, G, Strauss, A, Cowan-Jacob, S.W.
登録日2009-09-02
公開日2009-11-03
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes
J.Med.Chem., 52, 2009
1S0X
DownloadVisualize
BU of 1s0x by Molmil
Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A
分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Nuclear receptor ROR-alpha
著者Kallen, J, Schlaeppi, J.M, Bitsch, F, Delhon, I, Fournier, B.
登録日2004-01-05
公開日2004-02-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A
J.Biol.Chem., 279, 2004
5DJP
DownloadVisualize
BU of 5djp by Molmil
Crystal structure of human FPPS in complex with biaryl compound 5
分子名称: 4-(naphthalen-1-yl)-1H-indole-2-carboxylic acid, Farnesyl pyrophosphate synthase, PHOSPHATE ION
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DGM
DownloadVisualize
BU of 5dgm by Molmil
Crystal structure of human FPPS in complex with monophosphonate compound 7
分子名称: Farnesyl pyrophosphate synthase, PHOSPHATE ION, {2-[(phosphonomethyl)carbamoyl]-1H-benzo[g]indol-1-yl}acetic acid
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-08-28
公開日2016-07-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献A General Strategy for Targeting Drugs to Bone.
Angew.Chem.Int.Ed.Engl., 54, 2015
5DIQ
DownloadVisualize
BU of 5diq by Molmil
Crystal structure of human FPPS in complex with salicylic acid derivative 3a
分子名称: 2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-01
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJV
DownloadVisualize
BU of 5djv by Molmil
Crystal structure of human FPPS in complex with biaryl compound 8e
分子名称: 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-10-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJR
DownloadVisualize
BU of 5djr by Molmil
Crystal structure of human FPPS in complex with biaryl compound 6
分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
<12

 

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon