6WG3
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![BU of 6wg3 by Molmil](/molmil-images/mine/6wg3) | Cryo-EM structure of human Cohesin-NIPBL-DNA complex | 分子名称: | Cohesin subunit SA-1, DNA (51-MER), Double-strand-break repair protein rad21 homolog, ... | 著者 | Shi, Z.B, Gao, H, Bai, X.C, Yu, H. | 登録日 | 2020-04-04 | 公開日 | 2020-05-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
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6WGE
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![BU of 6wge by Molmil](/molmil-images/mine/6wge) | Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1 | 分子名称: | DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ... | 著者 | Shi, Z.B, Gao, H, Bai, X.C, Yu, H. | 登録日 | 2020-04-05 | 公開日 | 2020-05-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science, 368, 2020
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2FVO
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![BU of 2fvo by Molmil](/molmil-images/mine/2fvo) | Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1 | 分子名称: | Peptide chain release factor 1 | 著者 | Rawat, U, Gao, H, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. | 登録日 | 2006-01-31 | 公開日 | 2006-04-04 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12.8 Å) | 主引用文献 | Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM. J.Mol.Biol., 357, 2006
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7L4S
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2GOY
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![BU of 2goy by Molmil](/molmil-images/mine/2goy) | Crystal structure of assimilatory adenosine 5'-phosphosulfate reductase with bound APS | 分子名称: | ADENOSINE-5'-PHOSPHOSULFATE, IRON/SULFUR CLUSTER, adenosine phosphosulfate reductase | 著者 | Chartron, J, Carroll, K.S, Shiau, C, Gao, H, Leary, J.A, Bertozzi, C.R, Stout, C.D. | 登録日 | 2006-04-14 | 公開日 | 2006-09-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5'-Phosphosulfate Reductase. J.Mol.Biol., 364, 2006
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8XJ8
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![BU of 8xj8 by Molmil](/molmil-images/mine/8xj8) | The Cryo-EM structure of MPXV E5 C-terminal in complex with DNA | 分子名称: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | 著者 | Zhang, W, Liu, Y, Gao, H, Gan, J. | 登録日 | 2023-12-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Structural and functional insights into the helicase protein E5 of Mpox virus. Cell Discov, 10, 2024
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8XJ7
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![BU of 8xj7 by Molmil](/molmil-images/mine/8xj7) | The Cryo-EM structure of MPXV E5 in complex with DNA | 分子名称: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | 著者 | Zhang, W, Liu, Y, Gao, H, Gan, J. | 登録日 | 2023-12-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Structural and functional insights into the helicase protein E5 of Mpox virus. Cell Discov, 10, 2024
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8XJ6
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![BU of 8xj6 by Molmil](/molmil-images/mine/8xj6) | The Cryo-EM structure of MPXV E5 apo conformation | 分子名称: | AMP PHOSPHORAMIDATE, Monkeypox virus E5, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Zhang, W, Liu, Y, Gao, H, Gan, J. | 登録日 | 2023-12-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structural and functional insights into the helicase protein E5 of Mpox virus. Cell Discov, 10, 2024
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6M4J
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![BU of 6m4j by Molmil](/molmil-images/mine/6m4j) | SspA in complex with cysteine | 分子名称: | CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, SspA complex protein | 著者 | Liu, L, Gao, H. | 登録日 | 2020-03-07 | 公開日 | 2020-04-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System. Mbio, 11, 2020
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8K5R
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![BU of 8k5r by Molmil](/molmil-images/mine/8k5r) | CDK9/cyclin T1 in complex with KB-0742 | 分子名称: | (1S,3S)-N3-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine, Cyclin-T1, Cyclin-dependent kinase 9 | 著者 | Zhou, M, Li, H, Gao, H, Trotter, B.W, Freeman, D. | 登録日 | 2023-07-24 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.751 Å) | 主引用文献 | Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers. J.Med.Chem., 66, 2023
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3TL8
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7YEH
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![BU of 7yeh by Molmil](/molmil-images/mine/7yeh) | Cryo-EM structure of human OGT-OGA complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | 著者 | Lu, P, Liu, Y, Yu, H, Gao, H. | 登録日 | 2022-07-05 | 公開日 | 2023-07-12 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14, 2023
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7XYF
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7XYG
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7XXE
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2H5E
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6USN
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![BU of 6usn by Molmil](/molmil-images/mine/6usn) | Co-crystal structure of SPR with compound 5 | 分子名称: | (2-hydroxyphenyl)[3-methyl-1-(pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Huang, X, Wang, K. | 登録日 | 2019-10-28 | 公開日 | 2019-12-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | 主引用文献 | Virtual screening to identify potent sepiapterin reductase inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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7E6R
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![BU of 7e6r by Molmil](/molmil-images/mine/7e6r) | Crystal structure of HCoV-NL63 3C-like protease,pH5.6 | 分子名称: | 3C-like proteinase | 著者 | Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | 登録日 | 2021-02-23 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7E6L
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![BU of 7e6l by Molmil](/molmil-images/mine/7e6l) | Crystal structure of HCoV-NL63 3C-like protease,pH5.0 | 分子名称: | 3C-like proteinase | 著者 | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | 登録日 | 2021-02-22 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.78037143 Å) | 主引用文献 | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7E6M
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![BU of 7e6m by Molmil](/molmil-images/mine/7e6m) | Crystal structure of Human coronavirus NL63 3C-like protease | 分子名称: | 3C-like proteinase | 著者 | Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | 登録日 | 2021-02-22 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.83445024 Å) | 主引用文献 | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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7E6N
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![BU of 7e6n by Molmil](/molmil-images/mine/7e6n) | Crystal structure of HCoV-NL63 3C-like protease,pH5.2 | 分子名称: | 3C-like proteinase | 著者 | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | 登録日 | 2021-02-22 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8413 Å) | 主引用文献 | Crystal structures of human coronavirus NL63 main protease at different pH values Acta Crystallogr.,Sect.F, 77, 2021
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5HVU
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7DRI
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![BU of 7dri by Molmil](/molmil-images/mine/7dri) | Structure of SspE_CTD_41658 | 分子名称: | DUF1524 domain | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-28 | 公開日 | 2022-06-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRS
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![BU of 7drs by Molmil](/molmil-images/mine/7drs) | Structure of SspE_40224 | 分子名称: | SspE protein | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-29 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRR
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![BU of 7drr by Molmil](/molmil-images/mine/7drr) | Structure of SspE-R100A protein | 分子名称: | SspE protein | 著者 | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | 登録日 | 2020-12-29 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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