7L1Y
 
 | | Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium-xylobiose complex | | 分子名称: | 1,2-ETHANEDIOL, Exo-B-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | | 著者 | Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. | | 登録日 | 2020-12-15 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium.
Biotechnol.Bioeng., 118, 2021
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7L1W
 | | Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exo-B-1,4-beta-xylanase | | 著者 | Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. | | 登録日 | 2020-12-15 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium.
Biotechnol.Bioeng., 118, 2021
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7L1Z
 | | Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium - NT-truncated form | | 分子名称: | 1,2-ETHANEDIOL, Exo-B-1,4-beta-xylanase, SULFATE ION | | 著者 | Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. | | 登録日 | 2020-12-15 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium.
Biotechnol.Bioeng., 118, 2021
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6CIU
 | | Structure of a Thr-rich interface in an Azami Green tetramer | | 分子名称: | Azami-Green | | 著者 | Oi, C, Lim, C.S, Knecht, K.M, Xiong, Y, Regan, L. | | 登録日 | 2018-02-25 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A threonine zipper that mediates protein-protein interactions: Structure and prediction.
Protein Sci., 27, 2018
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3KD7
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2AVP
 | | Crystal structure of an 8 repeat consensus TPR superhelix | | 分子名称: | CADMIUM ION, synthetic consensus TPR protein | | 著者 | Kajander, T, Cortajarena, A.L, Main, E.R, Mochrie, S, Regan, L. | | 登録日 | 2005-08-30 | | 公開日 | 2005-09-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure and stability of designed TPR protein superhelices: unusual crystal packing and implications for natural TPR proteins.
Acta Crystallogr.,Sect.D, 63, 2007
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4C3O
 | | Structure and function of an oxygen tolerant NiFe hydrogenase from Salmonella | | 分子名称: | CHLORIDE ION, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ... | | 著者 | Bowman, L, Flanagan, L, Fyfe, P.K, Parkin, A, Hunter, W.N, Sargent, F. | | 登録日 | 2013-08-26 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | How the Structure of the Large Subunit Controls Function in an Oxygen-Tolerant [Nife]-Hydrogenase.
Biochem.J., 458, 2014
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2QND
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1NA3
 | | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif | | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | | 著者 | Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. | | 登録日 | 2002-11-26 | | 公開日 | 2003-06-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
Structure, 11, 2003
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1NA0
 | | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif | | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, ACETATE ION, CHLORIDE ION, ... | | 著者 | Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. | | 登録日 | 2002-11-26 | | 公開日 | 2003-06-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif
Structure, 11, 2003
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8U3M
 | | The FARFAR-MD-NMR ensemble of an HIV-1 TAR excited state | | 分子名称: | The excited state of HIV-1 transactivation response element (31-MER) | | 著者 | Geng, A, Ganser, L, Roy, R, Shi, H, Pratihar, S, Case, D.A, Al-Hashimi, H.M. | | 登録日 | 2023-09-07 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An RNA excited conformational state at atomic resolution.
Nat Commun, 14, 2023
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1XNF
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3ESK
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3FWV
 | | Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide | | 分子名称: | Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION | | 著者 | Jackrel, M.E, Valverde, R, Regan, L. | | 登録日 | 2009-01-19 | | 公開日 | 2009-04-21 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
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7T63
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4R6A
 | | Crystal structure of human TLR8 in complex with Hybrid-2 | | 分子名称: | 1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... | | 著者 | Tanji, H, Ohto, U, Shimizu, T. | | 登録日 | 2014-08-22 | | 公開日 | 2015-08-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Hybrid-2: AnImidazoquinoline Dual Toll-like receptor 7/8 Agonist that Potently Activates Cytokine Production by Human Newborn and Adult Leukocytes
To be Published
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6XKB
 | | Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD | | 分子名称: | S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION | | 著者 | Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2020-06-26 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
Febs Lett., 596, 2022
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8WCP
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8J0L
 | | Structure of DNA binding Domain of Human TFAP2A | | 分子名称: | GLYCEROL, Transcription factor AP-2-alpha | | 著者 | Liu, K, Xiao, Y.Q, Gan, L.Y, Min, J.R. | | 登録日 | 2023-04-11 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Nucleic Acids Res., 51, 2023
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6DKJ
 | | human GIPR ECD and Fab complex | | 分子名称: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | | 著者 | Min, X, Wang, Z. | | 登録日 | 2018-05-29 | | 公開日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.
Sci Transl Med, 10, 2018
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8J0K
 | | Crystal structure of human TFAP2A in complex with DNA | | 分子名称: | DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*GP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*CP*GP*AP*GP*GP*CP*AP*G)-3'), GLYCEROL, ... | | 著者 | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | | 登録日 | 2023-04-11 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Nucleic Acids Res., 51, 2023
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8J0Q
 | | Structure of DNA binding domain of human TFAP2B | | 分子名称: | GLYCEROL, Transcription factor AP-2-beta | | 著者 | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | | 登録日 | 2023-04-11 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Nucleic Acids Res., 51, 2023
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8J0R
 | | Structure of human TFAP2A in complex with DNA | | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*AP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*GP*AP*GP*GP*CP*AP*G)-3'), ... | | 著者 | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | | 登録日 | 2023-04-11 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Nucleic Acids Res., 51, 2023
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3E8K
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4ZO5
 | | PDE10 complexed with 4-isopropoxy-2-(2-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione | | 分子名称: | 2-{2-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}-4-(propan-2-yloxy)-1H-isoindole-1,3(2H)-dione, 3-(1-hydroxy-2-methylpropan-2-yl)-5-phenyl-3,5-dihydro-1H-imidazo[4,5-c][1,8]naphthyridine-2,4-dione, MAGNESIUM ION, ... | | 著者 | Yan, Y. | | 登録日 | 2015-05-06 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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