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3KN1
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BU of 3kn1 by Molmil
Crystal Structure of Golgi Phosphoprotein 3 N-term Truncation Variant
分子名称: Golgi phosphoprotein 3, SULFATE ION
著者Schmitz, K.R, Bessman, N.J, Setty, T.G, Ferguson, K.M.
登録日2009-11-11
公開日2009-12-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking.
J.Cell Biol., 187, 2009
2ZII
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BU of 2zii by Molmil
Crystal Structure of Yeast Vps74-N-term Truncation Variant
分子名称: Vacuolar protein sorting-associated protein 74
著者Schmitz, K.R, Li, S, Setty, T.G, Ferguson, K.M.
登録日2008-02-18
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Golgi localization of glycosyltransferases requires a Vps74p oligomer.
Dev.Cell, 14, 2008
2ZIH
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BU of 2zih by Molmil
Crystal Structure of Yeast Vps74
分子名称: Vacuolar protein sorting-associated protein 74
著者Schmitz, K.R, Li, S, Setty, T.G, Ferguson, K.M.
登録日2008-02-18
公開日2008-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Golgi localization of glycosyltransferases requires a Vps74p oligomer.
Dev.Cell, 14, 2008
1YY9
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BU of 1yy9 by Molmil
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ...
著者Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M.
登録日2005-02-24
公開日2005-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.605 Å)
主引用文献Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
1YY8
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BU of 1yy8 by Molmil
Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225
分子名称: Cetuximab Fab Heavy chain, Cetuximab Fab Light chain
著者Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M.
登録日2005-02-24
公開日2005-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
2AHX
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BU of 2ahx by Molmil
Crystal structure of ErbB4/HER4 extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4, SULFATE ION, ...
著者Bouyain, S, Longo, P.A, Li, S, Ferguson, K.M, Leahy, D.J.
登録日2005-07-28
公開日2005-09-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand
Proc.Natl.Acad.Sci.USA, 102, 2005
7LEN
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BU of 7len by Molmil
Crystal structure of the epidermal growth factor receptor extracellular region with R84K mutation in complex with epiregulin crystallized with trehalose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A.
登録日2021-01-14
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias.
Nature, 602, 2022
7LFS
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BU of 7lfs by Molmil
Crystal structure of the epidermal growth factor receptor extracellular region with A265V mutation in complex with epiregulin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 4 of Epidermal growth factor receptor, ...
著者Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A.
登録日2021-01-18
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias.
Nature, 602, 2022
7LFR
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Crystal structure of the epidermal growth factor receptor extracellular region with R84K mutation in complex with epiregulin crystallized with spermine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Proepiregulin, ...
著者Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A.
登録日2021-01-18
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias.
Nature, 602, 2022
5WI2
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BU of 5wi2 by Molmil
Crystal structure of the KA1 domain from human Chk1
分子名称: ACETATE ION, GLYCEROL, cDNA FLJ56409, ...
著者Emptage, R.P, Marmorstein, R.
登録日2017-07-18
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain.
J. Biol. Chem., 292, 2017
4WPC
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BU of 4wpc by Molmil
Crystal structure of Rgd1p F-BAR domain in complex with inositol phosphate
分子名称: INOSITOL HEXAKISPHOSPHATE, RHO GTPase-activating protein RGD1
著者Moravcevic, K, Lemmon, M.A.
登録日2014-10-17
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site.
Structure, 23, 2015
4WPE
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BU of 4wpe by Molmil
Crystal Structure of Hof1p F-BAR domain
分子名称: Cytokinesis protein 2
著者Lemmon, M.A, Moravcevic, K.
登録日2014-10-17
公開日2014-12-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site.
Structure, 23, 2015
6C9D
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BU of 6c9d by Molmil
Crystal structure of KA1-autoinhibited MARK1 kinase
分子名称: Serine/threonine-protein kinase MARK1,Serine/threonine-protein kinase MARK1
著者Emptage, R.P, Marmorstein, R.
登録日2018-01-26
公開日2018-07-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain.
Structure, 26, 2018
1EAZ
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BU of 1eaz by Molmil
Crystal structure of the phosphoinositol (3,4)-bisphosphate binding PH domain of TAPP1 from human.
分子名称: CITRIC ACID, TANDEM PH DOMAIN CONTAINING PROTEIN-1
著者Thomas, C.C, Dowler, S, Deak, M, Alessi, D.R, Van Aalten, D.M.F.
登録日2001-07-17
公開日2002-07-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity
Biochem.J., 358, 2001
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