8Q7N
 
 | | cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2023-08-16 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
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2OZB
 | | Structure of a human Prp31-15.5K-U4 snRNA complex | | 分子名称: | CALCIUM ION, RNA comprising the 5' Stem-Loop RNA of U4snRNA, U4/U6 small nuclear ribonucleoprotein Prp31, ... | | 著者 | Liu, S, Luehrmann, R, Wahl, M.C. | | 登録日 | 2007-02-26 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.
Science, 316, 2007
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5M88
 | | Spliceosome component | | 分子名称: | Core | | 著者 | Moura, T.R, Pena, V. | | 登録日 | 2016-10-28 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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5M89
 | | Spliceosome component | | 分子名称: | Spliceosome WD40 Sc | | 著者 | Moura, T.R, Pena, V. | | 登録日 | 2016-10-28 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.605 Å) | | 主引用文献 | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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5MS0
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5MQF
 | | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... | | 著者 | Bertram, K, Hartmuth, K, Kastner, B. | | 登録日 | 2016-12-20 | | 公開日 | 2017-03-22 | | 最終更新日 | 2018-11-21 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
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3TP2
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5HY7
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6FF7
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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6FF4
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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6Y53
 | | human 17S U2 snRNP low resolution part | | 分子名称: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | 登録日 | 2020-02-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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6Y5Q
 | | human 17S U2 snRNP | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | 登録日 | 2020-02-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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6Y50
 | | 5'domain of human 17S U2 snRNP | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | 登録日 | 2020-02-24 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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5LM7
 | | Crystal structure of the lambda N-Nus factor complex | | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | | 著者 | Said, N, Santos, K, Weber, G, Wahl, M.C. | | 登録日 | 2016-07-29 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
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5LM9
 | | Structure of E. coli NusA | | 分子名称: | MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA | | 著者 | Said, N, Weber, G, Santos, K, Wahl, M.C. | | 登録日 | 2016-07-29 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.143 Å) | | 主引用文献 | Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
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5LQW
 | | yeast activated spliceosome | | 分子名称: | Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... | | 著者 | Rauhut, R, Luehrmann, R. | | 登録日 | 2016-08-17 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016
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7PKS
 | | Structural basis of Integrator-mediated transcription regulation | | 分子名称: | DNA Template, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Fianu, I, Chen, Y, Dienemann, C, Cramer, P. | | 登録日 | 2021-08-26 | | 公開日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of Integrator-mediated transcription regulation.
Science, 374, 2021
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5M8C
 | | Spliceosome component | | 分子名称: | Pre-mRNA-processing factor 19 | | 著者 | Moura, T.R, Pena, V. | | 登録日 | 2016-10-28 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
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5O9Z
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6QHK
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6QH3
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6S98
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6S96
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7ABG
 | | Human pre-Bact-1 spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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7ABH
 | | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | | 分子名称: | Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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