4XC2
| Crystal structure of GABARAP in complex with KBTBD6 LIR peptide | 分子名称: | GABA(A) receptor-associated protein, Kelch repeat and BTB domain-containing protein 6 | 著者 | Huber, J, Genau, H.M, Baschieri, F, Doetsch, V, Farhan, H, Rogov, V.V, Behrends, C, Akutsu, M. | 登録日 | 2014-12-17 | 公開日 | 2015-03-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling. Mol.Cell, 57, 2015
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6XX0
| Crystal structure of NEMO in complex with Ubv-LIN | 分子名称: | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b, ... | 著者 | Akutsu, M, Skenderovic, A, Garcia-Pardo, J, Maculins, T, Dikic, I. | 登録日 | 2020-01-26 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, 27, 2020
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4WAA
| Crystal structure of Nix LIR-fused human LC3B_2-119 | 分子名称: | Microtubule-associated proteins 1A/1B light chain 3B | 著者 | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | 登録日 | 2014-08-29 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins. Sci Rep, 7, 2017
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6YEK
| Crystal structure of human NEMO apo form | 分子名称: | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b | 著者 | Garcia-Pardo, J, Akutsu, M, Busse, P, Skenderovic, A, Maculins, T, Dikic, I. | 登録日 | 2020-03-25 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, 27, 2020
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1A66
| SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES | 分子名称: | CORE NFATC1, DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3') | 著者 | Zhou, P, Sun, L.J, Doetsch, V, Wagner, G, Verdine, G.L. | 登録日 | 1998-03-06 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the core NFATC1/DNA complex. Cell(Cambridge,Mass.), 92, 1998
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4QVK
| Apo-crystal structure of Podospora anserina methyltransferase PaMTH1 | 分子名称: | 1,2-ETHANEDIOL, PaMTH1 Methyltransferase | 著者 | Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H. | 登録日 | 2014-07-15 | 公開日 | 2015-05-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J.Biol.Chem., 290, 2015
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7SAF
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7SAY
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4MRT
| Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | 分子名称: | 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ... | 著者 | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | 登録日 | 2013-09-17 | 公開日 | 2014-04-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
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4YMG
| Crystal structure of SAM-bound Podospora anserina methyltransferase PaMTH1 | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Putative SAM-dependent O-methyltranferase, ... | 著者 | Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H. | 登録日 | 2015-03-06 | 公開日 | 2015-05-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J.Biol.Chem., 290, 2015
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5J9P
| KcsA in vitro | 分子名称: | Fab, POTASSIUM ION, pH-gated potassium channel KcsA | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2016-04-10 | 公開日 | 2016-07-20 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Combining in Vitro Folding with Cell Free Protein Synthesis for Membrane Protein Expression. Biochemistry, 55, 2016
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4YMH
| Crystal structure of SAH-bound Podospora anserina methyltransferase PaMTH1 | 分子名称: | DI(HYDROXYETHYL)ETHER, Putative SAM-dependent O-methyltranferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H. | 登録日 | 2015-03-06 | 公開日 | 2015-05-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.876 Å) | 主引用文献 | Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. J.Biol.Chem., 290, 2015
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8P9D
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2 | 分子名称: | Darpin 1810 A2, Tumor protein 63, Tumor protein p73 | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-05 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
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8P9E
| Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | 分子名称: | Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ... | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-05 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
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8P9C
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | 分子名称: | 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ... | 著者 | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-05 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
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1GYF
| GYF DOMAIN FROM HUMAN CD2BP2 PROTEIN | 分子名称: | PROTEIN (CYTOPLASMIC DOMAIN BINDING PROTEIN (CD2BP2)) | 著者 | Freund, C, Doetsch, V, Nishizawa, K, Reinherz, E.L, Wagner, G. | 登録日 | 1999-04-30 | 公開日 | 2000-01-05 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences. Nat.Struct.Biol., 6, 1999
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3SJB
| Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | 分子名称: | ATPase GET3, Golgi to ER traffic protein 1, PHOSPHATE ION, ... | 著者 | Reitz, S, Wild, K, Sinning, I. | 登録日 | 2011-06-21 | 公開日 | 2011-07-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
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3SJC
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3SJA
| Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | 分子名称: | ATPase GET3, Golgi to ER traffic protein 1, PHOSPHATE ION, ... | 著者 | Reitz, S, Wild, K, Sinning, I. | 登録日 | 2011-06-21 | 公開日 | 2011-07-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
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3SJD
| Crystal structure of S. cerevisiae Get3 with bound ADP-Mg2+ in complex with Get2 cytosolic domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 2, ... | 著者 | Reitz, S, Wild, K, Sinning, I. | 登録日 | 2011-06-21 | 公開日 | 2011-07-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | 主引用文献 | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
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6HB9
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6H8C
| Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif | 分子名称: | Gamma-aminobutyric acid receptor-associated protein-like 2, Ubiquitin-like modifier-activating enzyme 5 | 著者 | Huber, J, Loehr, F, Gruber, J, Akutsu, M, Guentert, P, Doetsch, V, Rogov, V.V. | 登録日 | 2018-08-02 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 16, 2020
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7OVC
| Structure of the human UFC1 protein in complex with the UBA5 C-terminal UFC1-binding motif. | 分子名称: | Ubiquitin-fold modifier-conjugating enzyme 1, Ubiquitin-like modifier-activating enzyme 5 | 著者 | Wesch, W, Loehr, F, Rogova, N, Doetsch, V, Rogov, V.V. | 登録日 | 2021-06-14 | 公開日 | 2021-08-04 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1. Int J Mol Sci, 22, 2021
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5N2O
| Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome | 分子名称: | Tumor protein 63 | 著者 | Rinnenthal, J, Wuerz, J.M, Osterburg, C, Guentert, P, Doetsch, V. | 登録日 | 2017-02-08 | 公開日 | 2018-02-07 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8POK
| Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid environment | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HISTAMINE, ... | 著者 | Schnelle, K, Koeck, Z, Persechino, M, Umbach, S, Schihada, H, Januliene, D, Parey, K, Pockes, S, Kolb, P, Doetsch, V, Moeller, A, Hilger, D, Bernhard, F. | 登録日 | 2023-07-05 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment. Nat Commun, 15, 2024
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