3RPI
 
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6S8J
 | | Structure of ZEBOV GP in complex with 5T0180 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope Glycoprotein 1, Envelope glycoprotein, ... | | 著者 | Diskin, R, Cohen-Dvashi, H. | | 登録日 | 2019-07-10 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structural Basis for a Convergent Immune Response against Ebola Virus.
Cell Host Microbe, 27, 2020
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6S8I
 | | Structure of ZEBOV GP in complex with 3T0265 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Enveloped Glycoprotein 1, ... | | 著者 | Diskin, R, Cohen-Dvashi, H. | | 登録日 | 2019-07-10 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Structural Basis for a Convergent Immune Response against Ebola Virus.
Cell Host Microbe, 27, 2020
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6S8D
 | | Structure of ZEBOV GP in complex with 1T0227 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Heavy chain, ... | | 著者 | Diskin, R, Cohen-Dvashi, H. | | 登録日 | 2019-07-09 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structural Basis for a Convergent Immune Response against Ebola Virus.
Cell Host Microbe, 27, 2020
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8P4T
 | | The spike complex of the Lujo Virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, ... | | 著者 | Eilon-Ashkenazy, M, Diskin, R. | | 登録日 | 2023-05-23 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | The spike complex of the Lujo Virus
To Be Published
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4ZJF
 | | Crystal structure of GP1 - the receptor binding domain of Lassa virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein | | 著者 | Cohen-Dvashi, H, Cohen, N, Israeli, H, Diskin, R. | | 登録日 | 2015-04-29 | | 公開日 | 2015-05-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | | 主引用文献 | Molecular Mechanism for LAMP1 Recognition by Lassa Virus.
J.Virol., 89, 2015
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7A5O
 | | Human MUC2 AAs 21-1397 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D. | | 登録日 | 2020-08-21 | | 公開日 | 2020-10-21 | | 最終更新日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
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6TM2
 | | Human MUC2 AAs 21-1397 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D. | | 登録日 | 2019-12-03 | | 公開日 | 2020-10-21 | | 最終更新日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
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6GC2
 | | AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface | | 分子名称: | Heavy chain, Light Chain | | 著者 | Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J. | | 登録日 | 2018-04-17 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
Plos Comput.Biol., 15, 2019
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7B0B
 | | Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, IGK@ protein, ... | | 著者 | Borenstein-Katz, A, Diskin, R. | | 登録日 | 2020-11-19 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants.
Immunity, 56, 2023
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6GJC
 | | Structure of Mycobacterium tuberculosis Fatty Acid Synthase - I | | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase | | 著者 | Elad, N, Baron, S, Shakked, Z, Zimhony, O, Diskin, R. | | 登録日 | 2018-05-16 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.
Nat Commun, 9, 2018
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6GH8
 | | Crystal structure of GP1 domain of Lujo virus in complex with the first CUB domain of neuropilin-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glycoprotein, ... | | 著者 | Cohen-Dvashi, H, Kilimnik, I, Diskin, R. | | 登録日 | 2018-05-06 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structural basis for receptor recognition by Lujo virus.
Nat Microbiol, 3, 2018
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5OMI
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5NFF
 | | Crystal structure of GP1 receptor binding domain from Morogoro virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | | 著者 | Israeli, H, Cohen-Dvashi, H, Shulman, A, Shimon, A, Diskin, R. | | 登録日 | 2017-03-14 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.615 Å) | | 主引用文献 | Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses.
PLoS Pathog., 13, 2017
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5NSJ
 | | GP1 receptor-binding domain from Whitewater Arroyo mammarenavirus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pre-glycoprotein polyprotein GP complex, ... | | 著者 | Shimon, A, Shani, O, Diskin, R. | | 登録日 | 2017-04-26 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | | 主引用文献 | Structural Basis for Receptor Selectivity by the Whitewater Arroyo Mammarenavirus.
J. Mol. Biol., 429, 2017
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4JDT
 | | Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | | 著者 | Scharf, L, Diskin, R, Bjorkman, P.J. | | 登録日 | 2013-02-25 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | | 主引用文献 | Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2VSD
 | | crystal structure of CHIR-AB1 | | 分子名称: | CHIR AB1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Arnon, T.I, Kaiser, J.T, Bjorkman, P.J. | | 登録日 | 2008-04-22 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The Crystal Structure of Chir-Ab1: A Primordial Avian Classical Fc Receptor.
J.Mol.Biol., 381, 2008
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5T87
 | | Crystal structure of CDI complex from Cupriavidus taiwanensis LMG 19424 | | 分子名称: | CdiA toxin, CdiI immunity protein | | 著者 | Michalska, K, Joachimiak, G, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Proteins, 86 Suppl 1, 2018
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5FT2
 | | Sub-tomogram averaging of Lassa virus glycoprotein spike from virus- like particles at pH 5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX | | 著者 | Li, S, Zhaoyang, S, Pryce, R, Parsy, M.L, Fehling, S.K, Schlie, K, Siebert, C.A, Garten, W, Bowden, T.A, Strecker, T, Huiskonen, J.T. | | 登録日 | 2016-01-09 | | 公開日 | 2016-03-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (16.4 Å) | | 主引用文献 | Acidic Ph-Induced Conformations and Lamp1 Binding of the Lassa Virus Glycoprotein Spike.
Plos Pathog., 12, 2016
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6TM6
 | | MUC2 CysD1 domain | | 分子名称: | CALCIUM ION, Mucin-2 | | 著者 | Khmelnitsky, L, Fass, D. | | 登録日 | 2019-12-03 | | 公開日 | 2020-02-19 | | 最終更新日 | 2021-03-03 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
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4JPV
 | | Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Zhou, T, Moquin, S, Kwong, P.D. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.827 Å) | | 主引用文献 | Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
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4JPW
 | | Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ... | | 著者 | Acharya, P, Luongo, T, Zhou, T, Kwong, P.D. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | | 主引用文献 | Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell(Cambridge,Mass.), 153, 2013
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3OD6
 | | Crystal structure of p38alpha Y323T active mutant | | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Livnah, O, Tzarum, N. | | 登録日 | 2010-08-11 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.682 Å) | | 主引用文献 | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation.
J.Mol.Biol., 405, 2011
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3ODY
 | | Crystal structure of p38alpha Y323Q active mutant | | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Livnah, O, Tzarum, N. | | 登録日 | 2010-08-12 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation.
J.Mol.Biol., 405, 2011
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3ODZ
 | | Crystal structure of P38alpha Y323R active mutant | | 分子名称: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Livnah, O, Tzarum, N. | | 登録日 | 2010-08-12 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation.
J.Mol.Biol., 405, 2011
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