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2H79
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BU of 2h79 by Molmil
Crystal Structure of human TR alpha bound T3 in orthorhombic space group
分子名称: 3,5,3'TRIIODOTHYRONINE, THRA protein
著者Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I.
登録日2006-06-01
公開日2006-07-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
2H77
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BU of 2h77 by Molmil
Crystal structure of human TR alpha bound T3 in monoclinic space group
分子名称: 3,5,3'TRIIODOTHYRONINE, THRA protein
著者Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I.
登録日2006-06-01
公開日2006-07-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
5U0K
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BU of 5u0k by Molmil
C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA)
分子名称: Glutaminase liver isoform, mitochondrial
著者Ferreira, I.M, Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B.
登録日2016-11-24
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0I
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BU of 5u0i by Molmil
C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - tetragonal crystal form
分子名称: CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ...
著者Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B.
登録日2016-11-24
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.423 Å)
主引用文献The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0J
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BU of 5u0j by Molmil
C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - monoclinic crystal form
分子名称: Glutaminase kidney isoform, mitochondrial, SODIUM ION
著者Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B.
登録日2016-11-24
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5UQE
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BU of 5uqe by Molmil
Multidomain structure of human kidney-type glutaminase(KGA/GLS)
分子名称: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
著者Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B.
登録日2017-02-08
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
3JZC
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BU of 3jzc by Molmil
Crystal Structure of TR-beta bound to the selective thyromimetic TRIAC
分子名称: Thyroid hormone receptor beta, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
著者Nascimento, A.S, Dias, S.G.M, Nunes, F.M, Aparicio, R.
登録日2009-09-23
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Gaining ligand selectivity in thyroid hormone receptors via entropy.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HZF
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BU of 3hzf by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group
分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Aparicio, R, Bleicher, L, Polikarpov, I.
登録日2009-06-23
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
3ILZ
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BU of 3ilz by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group
分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Aparicio, R, Polikarpov, L, Bleicher, L.
登録日2009-08-07
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
3IMY
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BU of 3imy by Molmil
Structure of TR-beta bound to selective thyromimetic GC-1
分子名称: Thyroid hormone receptor beta, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Bleicher, L, Polikarpov, L, Aparicio, R.
登録日2009-08-11
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
BMC STRUCT.BIOL., 8, 2008
5F28
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BU of 5f28 by Molmil
Crystal structure of FAT domain of Focal Adhesion Kinase (FAK) bound to the transcription factor MEF2C
分子名称: Focal adhesion kinase 1, MEF2C
著者Cardoso, A.C, Ambrosio, A.L.B, Dessen, A, Franchini, K.G.
登録日2015-12-01
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes.
Structure, 24, 2016
8S5I
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BU of 8s5i by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction
分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5H
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BU of 8s5h by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, helical reconstruction
分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5K
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BU of 8s5k by Molmil
Full-length human cystathionine beta-synthase, basal state, single particle reconstruction
分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5J
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BU of 8s5j by Molmil
Full-length human cystathionine beta-synthase, basal state, helical reconstruction
分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5L
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BU of 8s5l by Molmil
Full-length human cystathionine beta-synthase, basal state, partially degraded tetramer
分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5M
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BU of 8s5m by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction
分子名称: Cystathionine beta-synthase, S-ADENOSYLMETHIONINE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
2OM9
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BU of 2om9 by Molmil
Ajulemic acid, a synthetic cannabinoid bound to PPAR gamma
分子名称: (6AR,10AR)-3-(1,1-DIMETHYLHEPTYL)-1-HYDROXY-6,6-DIMETHYL-6A,7,10,10A-TETRAHYDRO-6H-BENZO[C]CHROMENE-9-CARBOXYLIC ACID, Peroxisome proliferator-activated receptor gamma
著者Ambrosio, A.L.B, Garratt, R.C.
登録日2007-01-21
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ajulemic Acid, a Synthetic Nonpsychoactive Cannabinoid Acid, Bound to the Ligand Binding Domain of the Human Peroxisome Proliferator-activated Receptor gamma
J.Biol.Chem., 282, 2007
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