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Crystal Structure of KPT-330 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Baumhardt, J.M, Chook, Y.M.
登録日	2020-12-21
公開日	2021-01-27
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.944 Å)
主引用文献	Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

2M4M

Solution structure of the RRM domain of the hypothetical protein CAGL0M09691g from Candida glabrata
分子名称:	hypothetical protein
著者	Harris, R, Hillerich, B, Ahmed, M, Bonanno, J.B, Chamala, S, Evans, B, Lafleur, J, Hammonds, J, Washington, E, Stead, M, Love, J, Attonito, J, Patel, H, Seidel, R.D, Chook, Y.M, Rout, M.P, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
登録日	2013-02-07
公開日	2013-02-27
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of the RRM domain of the hypothetical protein CAGL0M09691g from Candida glabrata To be Published

5DHA

Crystal Structure of CPEB4 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Engineered Nuclear Export Signal Peptide (CPEB4 NES reverse mutant), Exportin-1, GLYCEROL, ...
著者	Fung, H.Y, Chook, Y.M.
登録日	2015-08-30
公開日	2015-09-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.95 Å)
主引用文献	Structural determinants of nuclear export signal orientation in binding to exportin CRM1. Elife, 4, 2015

5DIF

Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	CHLORIDE ION, Cytoplasmic polyadenylation element-binding protein 4, Exportin-1, ...
著者	Fung, H.Y, Chook, Y.M.
登録日	2015-08-31
公開日	2015-09-16
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.092 Å)
主引用文献	Structural determinants of nuclear export signal orientation in binding to exportin CRM1. Elife, 4, 2015

5DI9

Crystal Structure of hRio2 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称:	CHLORIDE ION, Engineered Nuclear Export Signal Peptide (hRio2 NES reverse mutant), Exportin-1, ...
著者	Fung, H.Y, Chook, Y.M.
登録日	2015-08-31
公開日	2015-09-16
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.28 Å)
主引用文献	Structural determinants of nuclear export signal orientation in binding to exportin CRM1. Elife, 4, 2015

2OT8

Karyopherin Beta2/Transportin-hnRNPM NLS Complex
分子名称:	Heterogeneous nuclear ribonucleoprotein M, Transportin-1
著者	Cansizoglu, A.E, Chook, Y.M.
登録日	2007-02-07
公開日	2007-04-10
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Structure-based design of a pathway-specific nuclear import inhibitor. Nat.Struct.Mol.Biol., 14, 2007

6XJP

Crystal Structure of KPT-185 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称:	Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者	Baumhardt, J.M, Chook, Y.M.
登録日	2020-06-24
公開日	2021-01-27
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.802 Å)
主引用文献	Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

6XJR

Crystal Structure of KPT-185 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ)
分子名称:	Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者	Baumhardt, J.M, Chook, Y.M.
登録日	2020-06-24
公開日	2021-01-27
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.941 Å)
主引用文献	Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

6XJU

Crystal Structure of KPT-8602 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ)
分子名称:	(2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ...
著者	Baumhardt, J.M, Chook, Y.M.
登録日	2020-06-24
公開日	2021-01-27
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.193 Å)
主引用文献	Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

6XJS

Crystal Structure of KPT-330 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ)
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Baumhardt, J.M, Chook, Y.M.
登録日	2020-06-24
公開日	2021-01-27
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.942 Å)
主引用文献	Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

6XJT

Crystal Structure of KPT-8602 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称:	(2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ...
著者	Baumhardt, J.M, Chook, Y.M.
登録日	2020-06-24
公開日	2021-01-27
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.406 Å)
主引用文献	Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021

5YVG

Crystal structure of Karyopherin beta2 in complex with FUS(full length)
分子名称:	RNA-binding protein FUS, Transportin-1
著者	Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
登録日	2017-11-25
公開日	2018-05-16
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (4.05 Å)
主引用文献	Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018

5YVH

Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
分子名称:	RNA-binding protein FUS, Transportin-1
著者	Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
登録日	2017-11-25
公開日	2018-05-16
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (3.15 Å)
主引用文献	Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018

5YVI

Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
分子名称:	RNA-binding protein FUS, Transportin-1
著者	Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
登録日	2017-11-25
公開日	2018-05-16
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018

5UWI

Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.143 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWU

Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	CHLORIDE ION, Exportin-1, GLYCEROL, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.24 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWQ

Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.278 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWW

Crystal Structure of DEAF1 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
分子名称:	Deformed epidermal autoregulatory factor 1 homolog, Exportin-1, GLYCEROL, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.152 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWJ

Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.221 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWR

Crystal Structure of CDC7 NES Peptide (extended) in complex with CRM1-Ran-RanBP1
分子名称:	CHLORIDE ION, Cell division cycle 7-related protein kinase, Exportin-1, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.24 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWP

Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.054 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWH

Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.26 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWO

Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.347 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWT

Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
分子名称:	Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.342 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

5UWS

Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称:	Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ...
著者	Fung, H.Y.J, Chook, Y.M.
登録日	2017-02-21
公開日	2017-03-22
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.401 Å)
主引用文献	Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

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