8SMQ
| Crystal Structure of the N-terminal Domain of the Cryptic Surface Protein (CD630_25440) from Clostridium difficile. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Kiryukhina, O, Wawrzak, Z, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2023-04-26 | 公開日 | 2023-05-10 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Protein target highlights in CASP15: Analysis of models by structure providers. Proteins, 91, 2023
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8DAQ
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8SCD
| Crystal structure of sulfonamide resistance enzyme Sul3 in complex with reaction intermediate | 分子名称: | 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, 4-AMINOBENZOIC ACID, CHLORIDE ION, ... | 著者 | Stogios, P.J, Venkatesan, M, Michalska, K, Mesa, N, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2023-04-05 | 公開日 | 2023-05-03 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics. Nat Commun, 14, 2023
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8SQN
| CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ... | 著者 | Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-05-04 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | 主引用文献 | Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8. Cell, 186, 2023
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8EBC
| Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Listeria monocytogenes in the complex with IMP | 分子名称: | FORMIC ACID, GLYCEROL, INOSINIC ACID, ... | 著者 | Kim, Y, Maltseva, N, Makowska-Grzyska, M, Osipiuk, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-08-31 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Listeria monocytogenes in the complex with IMP To Be Published
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8EW4
| Human Serum Albumin with Cobalt (II) and Myristic Acid - crystal 1 | 分子名称: | COBALT (II) ION, MYRISTIC ACID, Serum albumin | 著者 | Gucwa, M, Cooper, D.R, Unciano, J, Lea, K, Kim, L, Lenkiewicz, J, Starban, I, Stewart, A.J, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-10-21 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids Chem Sci, 14, 2023
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8EY5
| Human Serum Albumin with Cobalt (II) and Myristic Acid - crystal 3 | 分子名称: | COBALT (II) ION, MYRISTIC ACID, Serum albumin | 著者 | Gucwa, M, Cooper, D.R, Stewart, A.J, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-10-26 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids Chem Sci, 14, 2023
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8EW7
| Human Serum Albumin with Cobalt (II) and Myristic Acid - crystal 2 | 分子名称: | COBALT (II) ION, MYRISTIC ACID, Serum albumin | 著者 | Gucwa, M, Cooper, D.R, Stewart, A.J, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-10-21 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids Chem Sci, 14, 2023
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8T28
| The crystal structure of SrtC2 sortase from Actinomyces oris | 分子名称: | CHLORIDE ION, Class C sortase, PHOSPHATE ION | 著者 | Osipiuk, J, Chang, C, Ton-That, H.L, Ton-That, H, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-06-05 | 公開日 | 2024-04-17 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular basis for dual functions in pilus assembly modulated by the lid of a pilus-specific sortase. J.Biol.Chem., 300, 2024
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8UFM
| Crystal Structure of L516C/Y647C Mutant of SARS-Unique Domain (SUD) from SARS-CoV-2 | 分子名称: | ACETATE ION, FORMIC ACID, Papain-like protease nsp3, ... | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Rosas-Lemus, M, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-10-04 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal Structure of L516C/Y647C Mutant of SARS-Unique Domain (SUD) from SARS-CoV-2 To Be Published
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8UFL
| Crystal Structure of SARS-Unique Domain (SUD) of Nsp3 from SARS coronavirus | 分子名称: | CHLORIDE ION, Papain-like protease nsp3, SULFATE ION | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-10-04 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal Structure of SARS-Unique Domain (SUD) of Nsp3 from SARS coronavirus To Be Published
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8EP7
| Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in complex with NADP | 分子名称: | ACETIC ACID, Ketol-acid reductoisomerase (NADP(+)) 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Kim, Y, Maltseva, N, Osipiuk, J, Gu, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-10-05 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in the complex with NADP. To Be Published
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8EP6
| Crystal Structure of the Beta-lactamase Class D from Chitinophaga pinensis in complex with Avibactam | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, ACETIC ACID, Beta-lactamase Class D Cpin_0907 | 著者 | Maltseva, N, Kim, Y, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-10-05 | 公開日 | 2022-10-19 | 最終更新日 | 2023-02-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of the Beta-lactamase Class D from Chitinophaga pinensis in the complex with Avibactam. To Be Published
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8EWO
| Crystal structure of putative glyoxylase II from Pseudomonas aeruginosa | 分子名称: | CHLORIDE ION, GLYCEROL, PA1813, ... | 著者 | Stogios, P.J, Skarina, T, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-10-24 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Crystal structure of putative glyoxylase II from Pseudomonas aeruginosa To Be Published
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7UUM
| Crystal structure of aminoglycoside resistance enzyme ApmA, complex with paromomycin and coenzyme A | 分子名称: | Aminocyclitol acetyltransferase ApmA, COENZYME A, GLYCEROL, ... | 著者 | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
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7UUN
| Crystal structure of aminoglycoside resistance enzyme ApmA, complex with neomycin | 分子名称: | 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, NEOMYCIN | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Osipiuk, J, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
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7UUO
| Crystal structure of aminoglycoside resistance enzyme ApmA H135A mutant, complex with tobramycin and coenzyme A | 分子名称: | 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, COENZYME A, ... | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
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7UUL
| Crystal structure of aminoglycoside resistance enzyme ApmA, complex with kanamycin B and coenzyme A | 分子名称: | (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, ... | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2022-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
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8U00
| Crystal structure of metallo-beta-lactamase superfamily protein from Caulobacter vibrioides | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Kim, Y, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-08-28 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of metallo-beta-lactamase superfamily protein from Caulobacter vibrioides To Be Published
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8U12
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7UUK
| Crystal structure of aminoglycoside resistance enzyme ApmA, complex with tobramycin | 分子名称: | Aminocyclitol acetyltransferase ApmA, CHLORIDE ION, TOBRAMYCIN | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2023-04-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nat.Chem.Biol., 20, 2024
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7UUJ
| Crystal structure of aminoglycoside resistance enzyme ApmA, complex with gentamicin | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, ... | 著者 | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2023-04-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with gentamicin To Be Published
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8EWF
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8VLC
| Crystal structure of Zn-dependent hydrolase from Salmonella typhimurium LT2 | 分子名称: | 1,2-ETHANEDIOL, HARLDQ motif MBL-fold protein, SULFATE ION | 著者 | Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2024-01-11 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Zn-dependent hydrolase from Salmonella typhimurium LT2 To Be Published
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8TTP
| Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | 著者 | Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2023-08-14 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam to be published
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