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2VBJ
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Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VBO
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Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VNF
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BU of 2vnf by Molmil
MOLECULAR BASIS OF HISTONE H3K4ME3 RECOGNITION BY ING4
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, HISTONE H3, ...
著者Palacios, A, Munoz, I.G, Pantoja-Uceda, D, Marcaida, M.J, Torres, D, Martin-Garcia, J.M, Luque, I, Montoya, G, Blanco, F.J.
登録日2008-02-04
公開日2008-04-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Molecular Basis of Histone H3K4Me3 Recognition by Ing4
J.Biol.Chem., 283, 2008
2VS7
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The crystal structure of I-DmoI in complex with DNA and Ca
分子名称: 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*CP*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*G)-3', ACETATE ION, ...
著者Marcaida, M.J, Prieto, J, Redondo, P, Nadra, A.D, Alibes, A, Serrano, L, Grizot, S, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2008-04-21
公開日2008-11-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
4AFL
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BU of 4afl by Molmil
The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.
分子名称: INHIBITOR OF GROWTH PROTEIN 4
著者Culurgioni, S, Munoz, I.G, Moreno, A, Palacios, A, Villate, M, Palmero, I, Montoya, G, Blanco, F.J.
登録日2012-01-19
公開日2012-02-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.275 Å)
主引用文献Crystal Structure of Inhibitor of Growth 4 (Ing4) Dimerization Domain Reveals Functional Organization of Ing Family of Chromatin-Binding Proteins.
J.Biol.Chem., 287, 2012
2KG4
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Three-dimensional structure of human Gadd45alpha in solution by NMR
分子名称: Growth arrest and DNA-damage-inducible protein GADD45 alpha
著者Sanchez, R, Pantoja-Uceda, D, Prieto, J, Diercks, T, Campos-Olivas, R, Blanco, F.J.
登録日2009-03-04
公開日2009-03-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase
J.Biol.Chem., 285, 2010
2JTO
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BU of 2jto by Molmil
Solution Structure of Tick Carboxypeptidase Inhibitor
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.J.
登録日2007-08-03
公開日2008-07-15
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
Biochemistry, 47, 2008
2K1J
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Plan homeodomain finger of tumour supressor ING4
分子名称: Inhibitor of growth protein 4, ZINC ION
著者Palacios, A, Garcia, P, Padro, D, Lopez-Hernandez, E, Blanco, F.J.
登録日2008-03-05
公開日2008-04-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4.
Febs Lett., 580, 2006
2JA4
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Crystal structure of CD5 domain III reveals the fold of a group B scavenger cysteine-rich receptor
分子名称: T-CELL SURFACE GLYCOPROTEIN CD5
著者Rodamilans, B, Munoz, I.G, Sarrias, M.R, Lozano, F, Blanco, F.J, Montoya, G.
登録日2006-11-21
公開日2007-03-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal Structure of the Third Extracellular Domain of Cd5 Reveals the Fold of a Group B Scavenger Cysteine-Rich Receptor Domain.
J.Biol.Chem., 282, 2007
2O7M
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BU of 2o7m by Molmil
The C-terminal loop of the homing endonuclease I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold
分子名称: DNA endonuclease I-CreI
著者Prieto, J, Redondo, P, Padro, D, Blanco, F.J, Paques, F, Montoya, G.
登録日2006-12-11
公開日2007-10-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage
Nucleic Acids Res., 35, 2007
2OTT
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BU of 2ott by Molmil
Crystal structure of CD5_DIII
分子名称: T-cell surface glycoprotein CD5
著者Rodamilans, B.
登録日2007-02-09
公開日2007-03-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain.
J.Biol.Chem., 282, 2007
6FB6
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BU of 6fb6 by Molmil
Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with an altered version of its target DNA (Haemoglobin beta subunit gene) at 5NNN region in the presence of Manganese
分子名称: DNA (5'-D(*TP*CP*AP*GP*AP*CP*TP*TP*GP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*CP*TP*CP*CP*TP*GP*TP*GP*G)-3'), DNA (5'-D(P*AP*CP*AP*AP*GP*TP*CP*TP*GP*A)-3'), ...
著者Molina, R, Prieto, J.
登録日2017-12-18
公開日2018-07-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
6RS2
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BU of 6rs2 by Molmil
Structure of the Bateman module of human CNNM4.
分子名称: Metal transporter CNNM4
著者Corral-Rodriguez, M.A, Stuiver, M, Gomez-Garcia, I, Oyenarte, I, Gimenez, P, Ereno-Orbea, J, Diercks, T, Muller, D, Martinez-Cruz, L.A.
登録日2019-05-21
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.694 Å)
主引用文献Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
Int J Mol Sci, 20, 2019
1TUD
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
分子名称: ALPHA-SPECTRIN
著者Viguera, A.R, Serrano, L, Wilmanns, M.
登録日1996-02-29
公開日1996-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
8F5Q
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BU of 8f5q by Molmil
Crystal structure of human PCNA in complex with the PIP box of FBH1
分子名称: F-box DNA helicase 1, Proliferating cell nuclear antigen
著者Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
登録日2022-11-15
公開日2023-09-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
2K2X
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BU of 2k2x by Molmil
Solution Structure of Tick Carboxypeptidase Inhibitor at pH 3.5
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Y
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Solution structure of the folded domain of intermediate IIIa of Tick Carboxypeptidase Inhibitor
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Z
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Solution structure of the folded domain of intermediate IIIb of Tick Carboxypeptidase Inhibitor
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
3MXA
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Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
分子名称: DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
著者Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
登録日2010-05-07
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MX9
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Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
分子名称: CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
著者Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
登録日2010-05-07
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MXB
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Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
分子名称: CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
著者Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
登録日2010-05-07
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
1TRL
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BU of 1trl by Molmil
NMR SOLUTION STRUCTURE OF THE C-TERMINAL FRAGMENT 255-316 OF THERMOLYSIN: A DIMER FORMED BY SUBUNITS HAVING THE NATIVE STRUCTURE
分子名称: THERMOLYSIN FRAGMENT 255 - 316
著者Rico, M, Jimenez, M.A, Gonzalez, C, De Filippis, V, Fontana, A.
登録日1994-09-02
公開日1995-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of the C-terminal fragment 255-316 of thermolysin: a dimer formed by subunits having the native structure.
Biochemistry, 33, 1994
1TUC
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20
分子名称: ALPHA-SPECTRIN
著者Wilmanns, M, Serrano, L, Viguera, A.R.
登録日1996-02-29
公開日1996-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
6FB9
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Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with an altered version of its target DNA at 5NNN region in the presence of Manganese
分子名称: DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3'), DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*TP*GP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3'), ...
著者Molina, R, Prieto, J.
登録日2017-12-18
公開日2018-07-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
6FB5
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Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with an altered version of its target DNA (Haemoglobin beta subunit gene) at 5NNN region in the presence of Magnesium
分子名称: ACETATE ION, DNA (5'-D(*TP*CP*AP*GP*AP*CP*TP*TP*GP*TP*CP*CP*AP*CP*AP*GP*GP*AP*GP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*CP*TP*CP*CP*TP*GP*TP*GP*GP*AP*CP*AP*AP*GP*TP*CP*TP*GP*A)-3'), ...
著者Molina, R, Prieto, J.
登録日2017-12-18
公開日2018-07-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018

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