6G7M
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![BU of 6g7m by Molmil](/molmil-images/mine/6g7m) | Four-site variant (Y222C, C197S, C432S, C433S) of E. coli hydrogenase-2 | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2 large chain, ... | 著者 | Carr, S.B, Armstrong, F.A, Zhang, L, Beaton, S.E. | 登録日 | 2018-04-06 | 公開日 | 2019-04-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Direct visible light activation of a surface cysteine-engineered [NiFe]-hydrogenase by silver nanoclusters Energy Environ Sci, 2019
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2B76
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![BU of 2b76 by Molmil](/molmil-images/mine/2b76) | E. coli Quinol fumarate reductase FrdA E49Q mutation | 分子名称: | CITRATE ANION, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Maklashina, E, Iverson, T.M, Sher, Y, Kotlyar, V, Mirza, O, Andrell, J, Hudson, J.M, Armstrong, F.A, Cecchini, G. | 登録日 | 2005-10-03 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Fumarate Reductase and Succinate Oxidase Activity of Escherichia coli Complex II Homologs Are Perturbed Differently by Mutation of the Flavin Binding Domain J.Biol.Chem., 281, 2006
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1F5C
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![BU of 1f5c by Molmil](/molmil-images/mine/1f5c) | CRYSTAL STRUCTURE OF F25H FERREDOXIN 1 MUTANT FROM AZOTOBACTER VINELANDII AT 1.75 ANGSTROM RESOLUTION | 分子名称: | FE3-S4 CLUSTER, FERREDOXIN 1, IRON/SULFUR CLUSTER, ... | 著者 | Chen, K, Bonagura, C.A, Tilley, G.J, Jung, Y.S, Armstrong, F.A, Stout, C.D, Burgess, B.K. | 登録日 | 2000-06-13 | 公開日 | 2000-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of ferredoxin variants exhibiting large changes in [Fe-S] reduction potential. Nat.Struct.Biol., 9, 2002
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1F5B
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![BU of 1f5b by Molmil](/molmil-images/mine/1f5b) | CRYSTAL STRUCTURE OF F2H FERREDOXIN 1 MUTANT FROM AZOTOBACTER VINELANDII AT 1.75 ANGSTROM RESOLUTION | 分子名称: | FE3-S4 CLUSTER, FERREDOXIN 1, IRON/SULFUR CLUSTER | 著者 | Chen, K, Bonagura, C.A, Tilley, G.J, Jung, Y.S, Armstrong, F.A, Stout, C.D, Burgess, B.K. | 登録日 | 2000-06-13 | 公開日 | 2000-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Crystal structures of ferredoxin variants exhibiting large changes in [Fe-S] reduction potential. Nat.Struct.Biol., 9, 2002
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1FTC
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![BU of 1ftc by Molmil](/molmil-images/mine/1ftc) | Y13C MUTANT OF AZOTOBACTER VINELANDII FDI | 分子名称: | FE3-S4 CLUSTER, FERREDOXIN, IRON/SULFUR CLUSTER | 著者 | Kemper, M.A, Lloyd, S.J, Prasad, G.S, Stout, C.D, Fawcett, S, Armstrong, F.A, Burgess, B.K. | 登録日 | 1997-01-08 | 公開日 | 1997-04-01 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Y13C Azotobacter vinelandii ferredoxin I. A designed [Fe-S] ligand motif contains a cysteine persulfide. J.Biol.Chem., 272, 1997
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1PC4
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![BU of 1pc4 by Molmil](/molmil-images/mine/1pc4) | Crystal Structure of the P50A mutant of ferredoxin I at 1.65 A Resolution | 分子名称: | FE3-S4 CLUSTER, Ferredoxin I, IRON/SULFUR CLUSTER | 著者 | Camba, R, Jung, Y.S, Chen, K, Hunsicker-Wang, L.M, Burgess, B.K, Stout, C.D, Hirst, J, Armstrong, F.A. | 登録日 | 2003-05-15 | 公開日 | 2003-09-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I Biochemistry, 42, 2003
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1PC5
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![BU of 1pc5 by Molmil](/molmil-images/mine/1pc5) | Crystal Structure of the P50G Mutant of Ferredoxin I at 1.8 A Resolution | 分子名称: | FE3-S4 CLUSTER, Ferredoxin I, IRON/SULFUR CLUSTER | 著者 | Camba, R, Jung, Y.S, Chen, K, Hunsicker-Wang, L.M, Burgess, B.K, Stout, C.D, Hirst, J, Armstrong, F.A. | 登録日 | 2003-05-15 | 公開日 | 2003-09-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I Biochemistry, 42, 2003
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6G94
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![BU of 6g94 by Molmil](/molmil-images/mine/6g94) | |
4GD3
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![BU of 4gd3 by Molmil](/molmil-images/mine/4gd3) | Structure of E. coli hydrogenase-1 in complex with cytochrome b | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Volbeda, A, Fontecilla-Camps, J.C, Darnault, C. | 登録日 | 2012-07-31 | 公開日 | 2013-01-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal Structure of the O(2)-Tolerant Membrane-Bound Hydrogenase 1 from Escherichia coli in Complex with Its Cognate Cytochrome b. Structure, 21, 2013
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8BAY
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![BU of 8bay by Molmil](/molmil-images/mine/8bay) | Crystal Structure of IDH1 variant R132C S280F in complex with NADPH, Ca2+ and 3-butyl-2-oxoglutarate | 分子名称: | (R)-3-butyl-2-oxopentanedioic acid, (S)-3-butyl-2-oxopentanedioic acid, CALCIUM ION, ... | 著者 | Rabe, P, Schofield, C.J, Reinbold, R, Brewitz, L. | 登録日 | 2022-10-12 | 公開日 | 2022-11-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2. J.Biol.Chem., 299, 2023
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8POU
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![BU of 8pou by Molmil](/molmil-images/mine/8pou) | Crystal Structure of the C19G/C120G variant of the membrane-bound [NiFe]-Hydrogenase from Cupriavidus necator in the air-oxidized state at 1.65 A Resolution. | 分子名称: | CHLORIDE ION, FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, ... | 著者 | Schmidt, A, Kalms, J, Scheerer, P. | 登録日 | 2023-07-05 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Stepwise conversion of the Cys 6 [4Fe-3S] to a Cys 4 [4Fe-4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase. Chem Sci, 14, 2023
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8POV
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![BU of 8pov by Molmil](/molmil-images/mine/8pov) | Crystal Structure of the C19G/C120G variant of the membrane-bound [NiFe]-Hydrogenase from Cupriavidus necator in the H2-reduced state at 1.92 A Resolution. | 分子名称: | FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | 著者 | Schmidt, A, Kalms, J, Scheerer, P. | 登録日 | 2023-07-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Stepwise conversion of the Cys 6 [4Fe-3S] to a Cys 4 [4Fe-4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase. Chem Sci, 14, 2023
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8POW
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![BU of 8pow by Molmil](/molmil-images/mine/8pow) | Crystal Structure of the C19G variant of the membrane-bound [NiFe]-Hydrogenase from Cupriavidus necator in the air-oxidized state at 1.61 A Resolution. | 分子名称: | CHLORIDE ION, FE3-S4 CLUSTER, Fe4S4, ... | 著者 | Kalms, J, Schmidt, A, Scheerer, P. | 登録日 | 2023-07-05 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Stepwise conversion of the Cys 6 [4Fe-3S] to a Cys 4 [4Fe-4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase. Chem Sci, 14, 2023
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8PVM
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![BU of 8pvm by Molmil](/molmil-images/mine/8pvm) | formaldehyde-inhibited [FeFe]-hydrogenase CpI from Clostridium pasteurianum, variant C299D | 分子名称: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, FORMYL GROUP, ... | 著者 | Duan, J, Hofmann, E, Happe, T. | 登録日 | 2023-07-18 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Insights into the Molecular Mechanism of Formaldehyde Inhibition of [FeFe]-Hydrogenases. J.Am.Chem.Soc., 145, 2023
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8QM3
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![BU of 8qm3 by Molmil](/molmil-images/mine/8qm3) | |
7NEM
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![BU of 7nem by Molmil](/molmil-images/mine/7nem) | Hydrogenase-2 variant R479K - anaerobically oxidised form | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | 著者 | Carr, S.B. | 登録日 | 2021-02-04 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | A comprehensive structural and kinetic investigation of the role of the active-site argininein bidirectional hydrogen activation by the [NiFe]-hydrogenase "Hyd-2) from Escherichia coli To Be Published
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6YF4
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![BU of 6yf4 by Molmil](/molmil-images/mine/6yf4) | [FeFe]-hydrogenase I from Clostridium pasteurianum (CpI), variant E279D | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, Iron hydrogenase 1, ... | 著者 | Duan, J, Hofmann, E, Happe, T. | 登録日 | 2020-03-25 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | The roles of long-range proton-coupled electron transfer in the directionality and efficiency of [FeFe]-hydrogenases. Proc.Natl.Acad.Sci.USA, 117, 2020
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3EGW
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![BU of 3egw by Molmil](/molmil-images/mine/3egw) | The crystal structure of the NarGHI mutant NarH - C16A | 分子名称: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, ... | 著者 | Bertero, M.G, Rothery, R.A, Weiner, J.H, Strynadka, N.C.J. | 登録日 | 2008-09-11 | 公開日 | 2010-03-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | When width is more important than height: Barriers to electron transfer in E.coli nitrate reductase To be Published
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4C3O
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![BU of 4c3o by Molmil](/molmil-images/mine/4c3o) | Structure and function of an oxygen tolerant NiFe hydrogenase from Salmonella | 分子名称: | CHLORIDE ION, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ... | 著者 | Bowman, L, Flanagan, L, Fyfe, P.K, Parkin, A, Hunter, W.N, Sargent, F. | 登録日 | 2013-08-26 | 公開日 | 2014-01-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | How the Structure of the Large Subunit Controls Function in an Oxygen-Tolerant [Nife]-Hydrogenase. Biochem.J., 458, 2014
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1B0V
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![BU of 1b0v by Molmil](/molmil-images/mine/1b0v) | I40N MUTANT OF AZOTOBACTER VINELANDII FDI | 分子名称: | FE3-S4 CLUSTER, IRON/SULFUR CLUSTER, PROTEIN (FERREDOXIN) | 著者 | Sridhar, V, Prasad, G.S, Stout, C.D, Chen, K, Burgess, B.K. | 登録日 | 1998-11-12 | 公開日 | 2000-01-19 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Alteration of the reduction potential of the [4Fe-4S](2+/+) cluster of Azotobacter vinelandii ferredoxin I. J.Biol.Chem., 274, 1999
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3UQY
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![BU of 3uqy by Molmil](/molmil-images/mine/3uqy) | H2-reduced structure of E. coli hydrogenase-1 | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Volbeda, A, Fontecilla-Camps, J.C, Darnault, C. | 登録日 | 2011-11-21 | 公開日 | 2012-03-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli. Proc.Natl.Acad.Sci.USA, 109, 2012
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3USE
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![BU of 3use by Molmil](/molmil-images/mine/3use) | Crystal Structure of E. coli hydrogenase-1 in its as-isolated form | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Volbeda, A, Fontecilla-Camps, J.C, Darnault, C. | 登録日 | 2011-11-23 | 公開日 | 2012-03-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli. Proc.Natl.Acad.Sci.USA, 109, 2012
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3USC
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![BU of 3usc by Molmil](/molmil-images/mine/3usc) | Crystal Structure of E. coli hydrogenase-1 in a ferricyanide-oxidized form | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Volbeda, A, Fontecilla-Camps, J.C, Darnault, C. | 登録日 | 2011-11-23 | 公開日 | 2012-03-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli. Proc.Natl.Acad.Sci.USA, 109, 2012
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7PJM
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![BU of 7pjm by Molmil](/molmil-images/mine/7pjm) | Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and Ca2+/2-Oxoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J. | 登録日 | 2021-08-24 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
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7PJN
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![BU of 7pjn by Molmil](/molmil-images/mine/7pjn) | Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and inhibitor DS-1001B | 分子名称: | (E)-3-(1-(5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)isoxazole-4-carbonyl)-3-methyl-1H-indol-4-yl)acrylic acid, CITRIC ACID, GLYCEROL, ... | 著者 | Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J, Clifton, I.J. | 登録日 | 2021-08-24 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
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