1GG5
 
 | | CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION | | 分子名称: | 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | | 著者 | Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M. | | 登録日 | 2000-07-12 | | 公開日 | 2001-09-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones.
Structure, 9, 2001
|
|
1MAB
 | | RAT LIVER F1-ATPASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Bianchet, M.A, Amzel, L.M. | | 登録日 | 1998-08-06 | | 公開日 | 1998-09-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The 2.8-A structure of rat liver F1-ATPase: configuration of a critical intermediate in ATP synthesis/hydrolysis.
Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
2CK0
 | |
2BRA
 | | Structure of N-Terminal FAD Binding motif of mouse MICAL | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS | | 著者 | Nadella, M, Bianchet, M.A, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2005-05-04 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and activity of the axon guidance protein MICAL.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
|
|
1RYA
 | | Crystal Structure of the E. coli GDP-mannose mannosyl hydrolase in complex with GDP and MG | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GDP-mannose mannosyl hydrolase, ... | | 著者 | Gabelli, S.B, Bianchet, M.A, Legler, P.M, Mildvan, A.S, Amzel, L.M. | | 登録日 | 2003-12-20 | | 公開日 | 2004-06-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure and mechanism of GDP-mannose glycosyl hydrolase, a Nudix enzyme that cleaves at carbon instead of phosphorus.
Structure, 12, 2004
|
|
1SDW
 | | Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase with bound peptide and dioxygen | | 分子名称: | COPPER (II) ION, GLYCEROL, N-ALPHA-ACETYL-3,5-DIIODOTYROSYL-D-THREONINE, ... | | 著者 | Prigge, S.T, Eipper, B.A, Mains, R.E, Amzel, L.M. | | 登録日 | 2004-02-14 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex.
Science, 304, 2004
|
|
1KBQ
 | | Complex of Human NAD(P)H quinone Oxidoreductase with 5-methoxy-1,2-dimethyl-3-(4-nitrophenoxymethyl)indole-4,7-dione (ES936) | | 分子名称: | 5-METHOXY-1,2-DIMETHYL-3-(4-NITROPHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | | 著者 | Faig, M, Bianchet, M.A, Amzel, L.M. | | 登録日 | 2001-11-06 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches.
Biochemistry, 40, 2001
|
|
1KBO
 | | Complex of Human recombinant NAD(P)H:Quinone Oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione (ES1340) | | 分子名称: | 5-METHOXY-1,2-DIMETHYL-3-(PHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | | 著者 | Faig, M, Bianchet, M.A, Amzel, L.M. | | 登録日 | 2001-11-06 | | 公開日 | 2002-01-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches.
Biochemistry, 40, 2001
|
|
5I8U
 | | Crystal Structure of the RV1700 (MT ADPRASE) E142Q mutant | | 分子名称: | ADP-ribose pyrophosphatase, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | | 著者 | Thirawatananond, P, Kang, L.-W, Amzel, L.M, Gabelli, S.B. | | 登録日 | 2016-02-19 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis.
J. Bioenerg. Biomembr., 48, 2016
|
|
3VAE
 | | Crystal Structure of M. tuberculosis LD-transpeptidase type 2 with Modified Catalytic Cysteine (C354) | | 分子名称: | DI(HYDROXYETHYL)ETHER, LD-transpeptidase type 2 | | 著者 | Erdemli, S, Bianchet, M.A, Gupta, R, Lamichhane, G, Amzel, L.M. | | 登録日 | 2011-12-29 | | 公開日 | 2012-12-12 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2.
Structure, 20, 2012
|
|
1YUH
 | | FAB FRAGMENT | | 分子名称: | 4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID, 88C6/12 FAB (HEAVY CHAIN), 88C6/12 FAB (LIGHT CHAIN) | | 著者 | Yuhasz, S.C, Amzel, L.M, Parry, C, Strand, M. | | 登録日 | 1996-01-30 | | 公開日 | 1996-07-11 | | 最終更新日 | 2018-03-21 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural analysis of affinity maturation: the three-dimensional structures of complexes of an anti-nitrophenol antibody.
Mol.Immunol., 32, 1995
|
|
3MIC
 | | Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound azide obtained by co-crystallization | | 分子名称: | AZIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Chufan, E.E, Eipper, B.A, Mains, R.E, Amzel, L.M. | | 登録日 | 2010-04-10 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM)
J.Am.Chem.Soc., 132, 2010
|
|
3MIF
 | | Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound carbon monooxide (CO) | | 分子名称: | CARBON MONOXIDE, COPPER (II) ION, GLYCEROL, ... | | 著者 | Siebert, X, Chufan, E, Eipper, B.A, Mains, R.E, Amzel, L.M. | | 登録日 | 2010-04-10 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM)
J.Am.Chem.Soc., 132, 2010
|
|
3MLL
 | | Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound azide | | 分子名称: | AZIDE ION, COPPER (II) ION, NICKEL (II) ION, ... | | 著者 | Chufan, E.E, Eipper, B.A, Mains, R.E, Amzel, L.M. | | 登録日 | 2010-04-16 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Differential reactivity between two copper sites in peptidylglycine alpha-hydroxylating monooxygenase
J.Am.Chem.Soc., 132, 2010
|
|
3MIB
 | | Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound nitrite | | 分子名称: | COPPER (II) ION, GLYCEROL, NICKEL (II) ION, ... | | 著者 | Chufan, E.E, Eipper, B.A, Mains, R.E, Amzel, L.M. | | 登録日 | 2010-04-10 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM)
J.Am.Chem.Soc., 132, 2010
|
|
3MIE
 | | Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound azide obtained by soaking (50mM NaN3) | | 分子名称: | AZIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Chufan, E.E, Eipper, B.A, Mains, R.E, Amzel, L.M. | | 登録日 | 2010-04-10 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | | 主引用文献 | Differential Reactivity Between the Two Copper Sites of Peptidylglycine alpha-Hydroxylating Monooxygenase (PHM)
J.Am.Chem.Soc., 132, 2010
|
|
6E0T
 | | C-terminal domain of Fission Yeast OFD1 | | 分子名称: | Prolyl 3,4-dihydroxylase ofd1 | | 著者 | Bianchet, M.A, Amzel, L.M, Espenshade, P.J, Yeh, T. | | 登録日 | 2018-07-06 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor.
Structure, 19, 2011
|
|
5WM0
 | |
5WJA
 | | Crystal structure of H107A peptidylglycine alpha-hydroxylating monooxygenase (PHM) in complex with citrate | | 分子名称: | CITRATE ANION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-07-21 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
5WKW
 | | Crystal structure of apo wild type peptidylglycine alpha-hydroxylating monooxygenase (PHM) | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Peptidyl-glycine alpha-amidating monooxygenase | | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | | 登録日 | 2017-07-25 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
|
|
1CK0
 | |
4OVV
 | | Crystal Structure of PI3Kalpha in complex with diC4-PIP2 | | 分子名称: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, PHOSPHATE ION, Phosphatidylinositol 3-kinase regulatory subunit alpha, ... | | 著者 | Gabelli, S.B, Vogelstein, B, Miller, M, Amzel, L.M. | | 登録日 | 2014-01-14 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of nSH2 regulation and lipid binding in PI3K alpha.
Oncotarget, 5, 2014
|
|
4OVU
 | | Crystal Structure of p110alpha in complex with niSH2 of p85alpha | | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. | | 登録日 | 2014-01-14 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Structural basis of nSH2 regulation and lipid binding in PI3K alpha.
Oncotarget, 5, 2014
|
|
3CQO
 | |
2GSI
 | |
