3MLL

Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound azide

Summary for 3MLL

Entry DOI	10.2210/pdb3mll/pdb
Related	1PHM 3MIB 3MIC 3MID 3MIE 3MIF 3MIG 3MIH 3MLJ 3MLK
Descriptor	Peptidyl-glycine alpha-amidating monooxygenase, COPPER (II) ION, NICKEL (II) ION, ... (5 entities in total)
Functional Keywords	oxidoreductase, monooxygenase, bioactive peptide activation, ascorbate
Biological source	Rattus norvegicus (rat)
Cellular location	Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein: P14925
Total number of polymer chains	1
Total formula weight	35172.39
Authors	Chufan, E.E.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. (deposition date: 2010-04-16, release date: 2011-03-02, Last modification date: 2023-09-06)
Primary citation	Chufan, E.E.,Prigge, S.T.,Siebert, X.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. Differential reactivity between two copper sites in peptidylglycine alpha-hydroxylating monooxygenase J.Am.Chem.Soc., 132:15565-15572, 2010 Cited by PubMed: 20958070 DOI: 10.1021/ja103117r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation