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6O0X
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BU of 6o0x by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
分子名称: 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ...
著者Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
登録日2019-02-17
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
6O0Y
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BU of 6o0y by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
分子名称: 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ...
著者Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
登録日2019-02-17
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
6O0Z
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BU of 6o0z by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
分子名称: CRISPR-associated endonuclease Cas9/Csn1, non-target strand DNA, single guide RNA, ...
著者Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
登録日2019-02-17
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
4YE6
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BU of 4ye6 by Molmil
The crystal structure of the intact human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE9
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BU of 4ye9 by Molmil
The crystal structure of the G45V mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YYE
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BU of 4yye by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with the canonical tRNAThr and threonyl sulfamoyl adenylate
分子名称: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, SULFATE ION, Threonine--tRNA ligase, ...
著者Holman, K.M, Simonovic, M.
登録日2015-03-23
公開日2016-01-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA.
Nucleic Acids Res., 44, 2016
4WYN
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BU of 4wyn by Molmil
The crystal structure of the A109G mutant of RNase A
分子名称: Ribonuclease pancreatic
著者French, R.L, Gagne, D, Doucet, N, Simonovic, M.
登録日2014-11-17
公開日2015-11-18
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4ZDO
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BU of 4zdo by Molmil
The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4WYP
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BU of 4wyp by Molmil
The crystal structure of the A109G mutant of RNase A in complex with 5'AMP
分子名称: ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic
著者French, R.L, Gagne, D, Doucet, N, Simonovic, M.
登録日2014-11-17
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4WYZ
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BU of 4wyz by Molmil
The crystal structure of the A109G mutant of RNase A in complex with 3'UMP
分子名称: 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic
著者French, R.L, Gagne, D, Doucet, N, Simonovic, M.
登録日2014-11-18
公開日2015-11-18
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4ZDP
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BU of 4zdp by Molmil
The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDL
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BU of 4zdl by Molmil
The crystal structure of the T325S mutant of the human holo SepSecS
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, O-phosphoseryl-tRNA(Sec) selenium transferase
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4YE8
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BU of 4ye8 by Molmil
The crystal structure of the Y57H mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
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件を2024-10-16に公開中

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