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3KFO
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Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae
分子名称: GLYCEROL, Nucleoporin NUP133
著者Sampathkumar, P, Bonanno, J.B, Miller, S, Bain, K, Dickey, M, Gheyi, T, Almo, S.C, Rout, M, Sali, A, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2009-10-27
公開日2010-01-26
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex.
Proteins, 79, 2011
2GGE
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BU of 2gge by Molmil
Crystal Structure of Mandelate Racemase/Muconate Lactonizing Enzyme from Bacillus Subtilis complexed with MG++ at 1.8 A
分子名称: CHLORIDE ION, MAGNESIUM ION, yitF
著者Malashkevich, V.N, Sauder, J.M, Schwinn, K.D, Emtage, S, Thompson, D.A, Rutter, M.E, Dickey, M, Groshong, C, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Powell, A, Boice, A, Gheyi, T, Ozyurt, S, Atwell, S, Wasserman, S.R, Burley, S.K, Sali, A, Babbitt, P, Pieper, U, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-03-23
公開日2006-04-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structure of Mandelate Racemase/Muconate Lactonizing Enzyme from Bacillus Subtilis complexed with MG++ at 1.8 A
To be Published
1BO4
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BU of 1bo4 by Molmil
CRYSTAL STRUCTURE OF A GCN5-RELATED N-ACETYLTRANSFERASE: SERRATIA MARESCENS AMINOGLYCOSIDE 3-N-ACETYLTRANSFERASE
分子名称: COENZYME A, PROTEIN (SERRATIA MARCESCENS AMINOGLYCOSIDE-3-N-ACETYLTRANSFERASE), SPERMIDINE
著者Wolf, E, Vassilev, A, Makino, Y, Sali, A, Nakatani, Y, Burley, S.K.
登録日1998-08-08
公開日1998-10-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase.
Cell(Cambridge,Mass.), 94, 1998
1CMO
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BU of 1cmo by Molmil
IMMUNOGLOBULIN MOTIF DNA-RECOGNITION AND HETERODIMERIZATION FOR THE PEBP2/CBF RUNT-DOMAIN
分子名称: POLYOMAVIRUS ENHANCER BINDING PROTEIN 2
著者Nagata, T, Gupta, V, Sorce, D, Kim, W.Y, Sali, A, Chait, B.T, Shigesada, K, Ito, Y, Werner, M.H.
登録日1999-05-11
公開日2000-01-05
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain.
Nat.Struct.Biol., 6, 1999
1A5T
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BU of 1a5t by Molmil
CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III
分子名称: DELTA PRIME, ZINC ION
著者Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J.
登録日1998-02-18
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
2QJC
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BU of 2qjc by Molmil
Crystal structure of a putative diadenosine tetraphosphatase
分子名称: Diadenosine tetraphosphatase, putative, MANGANESE (II) ION, ...
著者Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-07-06
公開日2007-07-24
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
3TXN
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BU of 3txn by Molmil
Crystal structure of Rpn6 from Drosophila melanogaster, native data
分子名称: 26S proteasome regulatory complex subunit p42B, GLYCEROL, SULFATE ION
著者Pathare, G.R, Bracher, A.
登録日2011-09-23
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TXM
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Crystal structure of Rpn6 from Drosophila melanogaster, Gd(3+) complex
分子名称: 26S proteasome regulatory complex subunit p42B, GADOLINIUM ION, SULFATE ION
著者Pathare, G.R, Bracher, A.
登録日2011-09-23
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together.
Proc.Natl.Acad.Sci.USA, 109, 2012
4XX9
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BU of 4xx9 by Molmil
Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RF4
分子名称: (2-{[2-(2,6-dimethylphenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rettenmaier, T.J, Wells, J.A.
登録日2015-01-29
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking.
J.Med.Chem., 58, 2015
2G59
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BU of 2g59 by Molmil
Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase from Homo sapiens
分子名称: PHOSPHATE ION, Receptor-type tyrosine-protein phosphatase O
著者Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-02-22
公開日2006-03-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
6N1Z
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BU of 6n1z by Molmil
Importin-9 bound to H2A-H2B
分子名称: Histone H2A, Histone H2B 1.1, Importin-9
著者Tomchick, D.R, Chook, Y.M, Padavannil, A.
登録日2018-11-12
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife, 8, 2019
5LN3
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BU of 5ln3 by Molmil
The human 26S Proteasome at 6.8 Ang.
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P.
登録日2016-08-03
公開日2017-03-22
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.
Mol. Cell Proteomics, 16, 2017
7UK4
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BU of 7uk4 by Molmil
KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound
分子名称: Polyketide synthase PKS13, UNKNOWN LIGAND
著者Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M.
登録日2022-03-31
公開日2023-02-15
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (1.94 Å)
主引用文献Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Nat.Struct.Mol.Biol., 30, 2023
7KDT
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BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
分子名称: Mitochondrial import receptor subunit TOM70, ORF9b protein
著者QCRG Structural Biology Consortium
登録日2020-10-09
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
6URI
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BU of 6uri by Molmil
HIV-1 Nef in complex with the CD4 cytoplasmic domain and the AP2 clathrin adaptor complex
分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Jia, X, Kwon, Y.
登録日2019-10-23
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of CD4 downregulation by HIV-1 Nef.
Nat.Struct.Mol.Biol., 27, 2020
8FVZ
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BU of 8fvz by Molmil
PiPT Y150A
分子名称: CITRATE ANION, PHOSPHATE ION, Phosphate transporter
著者Gupta, M, Finer-Moore, J, Stroud, R.M.
登録日2023-01-20
公開日2024-01-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Roles of PiPT residues in phosphate binding and transport tested by mutagenesis
To be published
4M51
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BU of 4m51 by Molmil
Crystal structure of amidohydrolase nis_0429 (ser145ala mutant) from nitratiruptor sp. sb155-2
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Amidohydrolase family protein, BENZOIC ACID, ...
著者Patskovsky, Y, Toro, R, Gobble, A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2013-08-07
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes.
Biochemistry, 52, 2013
4IFQ
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BU of 4ifq by Molmil
Crystal structure of Saccharomyces cerevisiae NUP192, residues 2 to 960 [ScNup192(2-960)]
分子名称: IODIDE ION, Nucleoporin NUP192, SULFATE ION
著者Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
登録日2012-12-14
公開日2013-02-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Structure, 21, 2013
2FH7
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BU of 2fh7 by Molmil
Crystal structure of the phosphatase domains of human PTP SIGMA
分子名称: Receptor-type tyrosine-protein phosphatase S
著者Alvarado, J, Udupi, R, Smith, D, Koss, J, Wasserman, S.R, Ozyurt, S, Atwell, S, Powell, A, Kearins, M.C, Rooney, I, Maletic, M, Bain, K.T, Freeman, J.C, Russell, M, Thompson, D.A, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-12-23
公開日2006-01-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
5TVZ
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BU of 5tvz by Molmil
Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820
分子名称: Nucleoporin POM152
著者Dutta, K, Sampathkumar, P, Cowburn, D, Almo, S.C, Rout, M.P, Fernandez-Martinez, J.
登録日2016-11-10
公開日2017-02-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Structure, 25, 2017
4K1C
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BU of 4k1c by Molmil
VCX1 Calcium/Proton Exchanger
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, IODIDE ION, ...
著者Waight, A.B, Pedersen, B.P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2013-04-04
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for alternating access of a eukaryotic calcium/proton exchanger.
Nature, 499, 2013
8C8J
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Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, ...
著者Nichols, C.E, Walpole, T.B, Baldwin, E.
登録日2023-01-20
公開日2023-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
2ER7
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X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION
分子名称: ENDOTHIAPEPSIN, SULFATE ION, TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN
著者Veerapandian, B, Cooper, J.B, Szelke, M, Blundell, T.L.
登録日1990-11-12
公開日1991-01-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
J.Mol.Biol., 216, 1990
5L1Z
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TAR complex with HIV-1 Tat-AFF4-P-TEFb
分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ...
著者Schulze-Gahmen, U, Hurley, J.
登録日2016-07-29
公開日2016-10-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Elife, 5, 2016
5YVG
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Crystal structure of Karyopherin beta2 in complex with FUS(full length)
分子名称: RNA-binding protein FUS, Transportin-1
著者Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
登録日2017-11-25
公開日2018-05-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.05 Å)
主引用文献Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018

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