2HUF
 
 | | Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase | | 分子名称: | 1-BUTANOL, Alanine glyoxylate aminotransferase | | 著者 | Han, Q, Robinson, H, Gao, Y.G, Vogelaar, N, Wilson, S.R, Rizzi, M, Li, J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem., 281, 2006
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2B1L
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2FJ2
 | | Crystal Structure of Viral Macrophage Inflammatory Protein-II | | 分子名称: | Viral macrophage inflammatory protein-II | | 著者 | Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z. | | 登録日 | 2005-12-30 | | 公開日 | 2006-12-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of chemically synthesized vMIP-II.
Proteins, 67, 2007
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2FHT
 | | Crystal Structure of Viral Macrophage Inflammatory Protein-II | | 分子名称: | Viral macrophage inflammatory protein-II | | 著者 | Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z. | | 登録日 | 2005-12-27 | | 公開日 | 2006-12-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of chemically synthesized vMIP-II.
Proteins, 67, 2007
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2HUI
 | | Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase in complex with glyoxylic acid | | 分子名称: | Alanine glyoxylate aminotransferase, GLYOXYLIC ACID | | 著者 | Han, Q, Robinson, H, Gao, Y.G, Vogelaar, N, Wilson, S.R, Rizzi, M, Li, J. | | 登録日 | 2006-07-26 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem., 281, 2006
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2HUU
 | | Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase in complex with alanine | | 分子名称: | 1-BUTANOL, ALANINE, Alanine glyoxylate aminotransferase | | 著者 | Han, Q, Robinson, H, Gao, Y.G, Vogelaar, N, Wilson, S.R, Rizzi, M, Li, J. | | 登録日 | 2006-07-27 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
J.Biol.Chem., 281, 2006
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2OPN
 | | Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527 | | 分子名称: | Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)], MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Cao, R, Gao, Y.G, Robinson, H, Goddard, A, Oldfield, E. | | 登録日 | 2007-01-29 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Bisphosphonates: Teaching Old Drugs with New Tricks
To be Published
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2QMT
 | | Crystal Polymorphism of Protein GB1 Examined by Solid-state NMR and X-ray Diffraction | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ISOPROPYL ALCOHOL, Immunoglobulin G-binding protein G, ... | | 著者 | Frericks Schmidt, H.L, Sperling, L.J, Gao, Y.G, Wylie, B.J, Boettcher, J.M, Wilson, S.R, Rienstra, C.M. | | 登録日 | 2007-07-16 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Crystal Polymorphism of Protein GB1 Examined by Solid-State NMR Spectroscopy and X-ray Diffraction.
J.Phys.Chem.B, 111, 2007
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2OPM
 | | Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461 | | 分子名称: | 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)], MAGNESIUM ION, ... | | 著者 | Cao, R, Gao, Y.G, Robinson, H, Goddard, A. | | 登録日 | 2007-01-29 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
J.Am.Chem.Soc., 131, 2009
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2R5C
 | | Aedes Kynurenine Aminotransferase in Complex with Cysteine | | 分子名称: | Kynurenine aminotransferase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | | 著者 | Han, Q, Gao, Y.G, Robinson, H, Li, J. | | 登録日 | 2007-09-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase.
Biochemistry, 47, 2008
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1VAQ
 | | Crystal structure of the Mg2+-(chromomycin A3)2-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by metal ion | | 分子名称: | (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... | | 著者 | Hou, M.H, Robinson, H, Gao, Y.G, Wang, A.H.-J. | | 登録日 | 2004-02-19 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion
Nucleic Acids Res., 32, 2004
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1YIY
 | | Aedes aegypti kynurenine aminotransferase | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BROMIDE ION, kynurenine aminotransferase; glutamine transaminase K | | 著者 | Han, Q, Gao, Y.G, Robinson, H, Ding, H, Wilson, S, Li, J. | | 登録日 | 2005-01-13 | | 公開日 | 2005-05-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of Aedes aegypti kynurenine aminotransferase.
FEBS J., 272, 2005
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1YIZ
 | | Aedes aegypti kynurenine aminotrasferase | | 分子名称: | BROMIDE ION, kynurenine aminotransferase; glutamine transaminase | | 著者 | Han, Q, Gao, Y.G, Robinson, H, Ding, H, Wilson, S, Li, J. | | 登録日 | 2005-01-13 | | 公開日 | 2005-05-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structures of Aedes aegypti kynurenine aminotransferase.
FEBS J., 272, 2005
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2B1K
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4O8B
 | | Crystal structure of transcriptional regulator BswR | | 分子名称: | Uncharacterized protein | | 著者 | Ye, F.Z, Wang, C, Kumar, V, Zhang, L.H, Gao, Y.G. | | 登録日 | 2013-12-26 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ.
Nucleic Acids Res., 42, 2014
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5IMR
 | | Structure of ribosome bound to cofactor at 5.7 angstrom resolution | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. | | 登録日 | 2016-03-06 | | 公開日 | 2016-05-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
J.Biol.Chem., 291, 2016
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5IMQ
 | | Structure of ribosome bound to cofactor at 3.8 angstrom resolution | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. | | 登録日 | 2016-03-06 | | 公開日 | 2016-05-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
J.Biol.Chem., 291, 2016
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4CXX
 | | Crystal structure of human FTO in complex with acylhydrazine inhibitor 16 | | 分子名称: | (2E)-4-{N'-[4-(4-tert-Butyl-benzyl)-pyridine-3-carbonyl]-hydrazino}-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION | | 著者 | Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. | | 登録日 | 2014-04-09 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Chem Sci, 6, 2015
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4CXW
 | | Crystal structure of human FTO in complex with subfamily-selective inhibitor 12 | | 分子名称: | (2E)-4-[N'-(4-benzyl-pyridine-3-carbonyl)-hydrazino]-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION | | 著者 | Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. | | 登録日 | 2014-04-09 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Chem Sci, 6, 2015
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4D6V
 | | Crystal structure of signal transducing protein | | 分子名称: | G PROTEIN BETA SUBUNIT GIB2 | | 著者 | Ero, R, Dimitrova, V.T, Chen, Y, Bu, W, Feng, S, Liu, T, Wang, P, Xue, C, Tan, S.M, Gao, Y.G. | | 登録日 | 2014-11-17 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Gib2, a Signal-Transducing Protein Scaffold Associated with Ribosomes in Cryptococcus Neoformans.
Sci.Rep., 5, 2015
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4CXY
 | | Crystal structure of human FTO in complex with acylhydrazine inhibitor 21 | | 分子名称: | (E)-4-(2-Nicotinoylhydrazinyl)-4-oxobut-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION | | 著者 | Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. | | 登録日 | 2014-04-09 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Chem Sci, 6, 2015
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6IEJ
 | | The C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholine | | 分子名称: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CALCIUM ION, Cytosolic phospholipase A2, ... | | 著者 | Hirano, Y, Gao, Y.G, Stephenson, D.J, Vu, N.T, Malinina, L, Chalfant, C.E, Patel, D.J, Brown, R.E. | | 登録日 | 2018-09-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Elife, 8, 2019
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6IUY
 | | Structure of DsGPDH of Dunaliella salina | | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, GLYCEROL, Glycerol-3-phosphate dehydrogenase [NAD(+)], ... | | 著者 | He, Q, Toh, J.D, Ero, R, Qiao, Z, Kumar, V, Gao, Y.G. | | 登録日 | 2018-12-01 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The unusual di-domain structure of Dunaliella salina glycerol-3-phosphate dehydrogenase enables direct conversion of dihydroxyacetone phosphate to glycerol.
Plant J., 102, 2020
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6KFS
 | | Structure of CCM related protein | | 分子名称: | LCIB_C_CA domain-containing protein, ZINC ION | | 著者 | Jin, S, Gao, Y.G. | | 登録日 | 2019-07-08 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural and biochemical characterization of novel carbonic anhydrases from Phaeodactylum tricornutum.
Acta Crystallogr D Struct Biol, 76, 2020
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7C3M
 | | Structure of FERM protein | | 分子名称: | Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3 | | 著者 | Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G. | | 登録日 | 2020-05-13 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state.
Plos Biol., 18, 2020
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