3L1E
 
 | | Bovine AlphaA crystallin Zinc Bound | | 分子名称: | Alpha-crystallin A chain, GLYCEROL, ZINC ION | | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2009-12-11 | | 公開日 | 2010-05-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.
Protein Sci., 19, 2010
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3L1G
 | | Human AlphaB crystallin | | 分子名称: | Alpha-crystallin B chain, SULFATE ION | | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2009-12-11 | | 公開日 | 2010-05-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.
Protein Sci., 19, 2010
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6DKQ
 | | Crystal structure of the Shr Hemoglobin Interacting Domain 2 | | 分子名称: | Heme-binding protein Shr, SULFATE ION | | 著者 | Macdonald, R, Cascio, D, Collazo, M.J, Clubb, R.T. | | 登録日 | 2018-05-30 | | 公開日 | 2018-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Streptococcus pyogenes Shr protein captures human hemoglobin using two structurally unique binding domains.
J.Biol.Chem., 293, 2018
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3L2X
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7SXN
 | | Orb2A residues 1-9 MYNKFVNFI | | 分子名称: | Orb2A residues 1-9 MYNKFVNFI | | 著者 | Bowler, J.T, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | | 登録日 | 2021-11-23 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.05 Å) | | 主引用文献 | Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like beta-sheets.
J.Biol.Chem., 298, 2022
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3AL1
 | | DESIGNED PEPTIDE ALPHA-1, RACEMIC P1BAR FORM | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ETHANOLAMINE, PROTEIN (D, ... | | 著者 | Patterson, W.R, Anderson, D.H, Degrado, W.F, Cascio, D, Eisenberg, D. | | 登録日 | 1998-10-26 | | 公開日 | 1998-11-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.75 Å) | | 主引用文献 | Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1.
Protein Sci., 8, 1999
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2RIF
 | | CBS domain protein PAE2072 from Pyrobaculum aerophilum complexed with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, CESIUM ION, Conserved protein with 2 CBS domains | | 著者 | Lee, T.M, King, N.P, Sawaya, M.R, Cascio, D, Yeates, T.O. | | 登録日 | 2007-10-10 | | 公開日 | 2008-06-17 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structures and Functional Implications of an AMP-Binding Cystathionine beta-Synthase Domain Protein from a Hyperthermophilic Archaeon.
J.Mol.Biol., 380, 2008
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2RIH
 | | CBS domain protein PAE2072 from Pyrobaculum aerophilum | | 分子名称: | ACETIC ACID, Conserved protein with 2 CBS domains, SULFATE ION | | 著者 | Lee, T.M, King, N.P, Sawaya, M.R, Cascio, D, Yeates, T.O. | | 登録日 | 2007-10-10 | | 公開日 | 2008-06-17 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures and Functional Implications of an AMP-Binding Cystathionine beta-Synthase Domain Protein from a Hyperthermophilic Archaeon
J.Mol.Biol., 380, 2008
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1RLC
 | | CRYSTAL STRUCTURE OF THE UNACTIVATED RIBULOSE 1, 5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE COMPLEXED WITH A TRANSITION STATE ANALOG, 2-CARBOXY-D-ARABINITOL 1,5-BISPHOSPHATE | | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (LARGE CHAIN), RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (SMALL CHAIN) | | 著者 | Zhang, K.Y.J, Cascio, D, Eisenberg, D. | | 登録日 | 1993-08-04 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the unactivated ribulose 1,5-bisphosphate carboxylase/oxygenase complexed with a transition state analog, 2-carboxy-D-arabinitol 1,5-bisphosphate.
Protein Sci., 3, 1994
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6WQK
 | | hnRNPA2 Low complexity domain (LCD) determined by cryoEM | | 分子名称: | MCherry fluorescent protein,Heterogeneous nuclear ribonucleoproteins A2/B1 chimera | | 著者 | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | | 登録日 | 2020-04-29 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid.
Nat Commun, 11, 2020
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6WPQ
 | | GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant | | 分子名称: | Heterogeneous nuclear ribonucleoprotein A2 | | 著者 | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | | 登録日 | 2020-04-27 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid.
Nat Commun, 11, 2020
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3KX9
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4ZNN
 | | MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56 | | 分子名称: | Alpha-synuclein | | 著者 | Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. | | 登録日 | 2015-05-05 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.41 Å) | | 主引用文献 | Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
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4ZK7
 | | Crystal structure of rescued two-component self-assembling tetrahedral cage T33-31 | | 分子名称: | Chorismate mutase, Divalent-cation tolerance protein CutA | | 著者 | Liu, Y, Cascio, D, Sawaya, M.R, Bale, J, Collazo, M.J, Park, R, King, N, Baker, D, Yeates, T. | | 登録日 | 2015-04-30 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.
Protein Sci., 24, 2015
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7QYD
 | | mosquitocidal Cry11Ba determined at pH 6.5 from naturally-occurring nanocrystals by Serial femtosecond crystallography | | 分子名称: | Pesticidal crystal protein Cry11Ba | | 著者 | De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P, Sawaya, M.R, Schibrowsky, N.A, Cascio, D, Rodriguez, J.A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
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7R1E
 | | Mosquitocidal Cry11Ba determined at pH 10.4 from naturally-occurring nanocrystals by Serial femtosecond crystallography | | 分子名称: | GLYCEROL, Pesticidal crystal protein Cry11Ba | | 著者 | Colletier, J.-P, Sawaya, M.R, Schibrowsky, N.A, Cascio, D, Rodriguez, J.A. | | 登録日 | 2022-02-02 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
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1ZUR
 | | Crystal structure of spin labeled T4 Lysozyme (V131R1F) | | 分子名称: | CHLORIDE ION, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | 著者 | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | | 登録日 | 2005-05-31 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of spin labeled T4 Lysozyme (V131R1F)
To be Published
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1ZWN
 | | Crystal structure of spin labeled T4 Lysozyme (V131R1B) | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | | 著者 | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | | 登録日 | 2005-06-03 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of spin labeled T4 Lysozyme (V131R1B)
To be Published
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2A4T
 | | Crystal structure of spin labeled T4 Lysozyme (V131R7) | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | | 著者 | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | | 登録日 | 2005-06-29 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of spin labeled T4 Lysozyme (V131R7
To be Published
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1ZYT
 | | Crystal structure of spin labeled T4 Lysozyme (A82R1) | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | | 著者 | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | | 登録日 | 2005-06-10 | | 公開日 | 2006-08-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | EPR (1.7 Å), X-RAY DIFFRACTION | | 主引用文献 | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
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3UID
 | | Crystal Structure of Protein Ms6760 from Mycobacterium smegmatis | | 分子名称: | Putative uncharacterized protein | | 著者 | Bajaj, R.A, Miallau, L, Cascio, D, Arbing, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-11-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.571 Å) | | 主引用文献 | Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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1BYZ
 | | DESIGNED PEPTIDE ALPHA-1, P1 FORM | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | | 著者 | Prive, G.G, Anderson, D.H, Wesson, L, Cascio, D, Eisenberg, D. | | 登録日 | 1998-10-20 | | 公開日 | 1998-10-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Packed protein bilayers in the 0.90 A resolution structure of a designed alpha helical bundle.
Protein Sci., 8, 1999
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1COS
 | | CRYSTAL STRUCTURE OF A SYNTHETIC TRIPLE-STRANDED ALPHA-HELICAL BUNDLE | | 分子名称: | COILED SERINE | | 著者 | Lovejoy, B, Choe, S, Cascio, D, Mcrorie, D.K, Degrado, W, Eisenberg, D. | | 登録日 | 1993-01-22 | | 公開日 | 1993-10-31 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of a synthetic triple-stranded alpha-helical bundle.
Science, 259, 1993
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6T1A
 | | Structure of mosquitocidal Cyt1Aa protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 10 | | 分子名称: | CALCIUM ION, Type-1Aa cytolytic delta-endotoxin | | 著者 | Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P. | | 登録日 | 2019-10-03 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
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6T14
 | | Native structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7 | | 分子名称: | SODIUM ION, Type-1Aa cytolytic delta-endotoxin | | 著者 | Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P. | | 登録日 | 2019-10-03 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade.
Nat Commun, 11, 2020
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