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4F87
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BU of 4f87 by Molmil
X-ray Crystal Structure of PlyCB
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PlyCB
著者McGowan, S, Buckle, A.M, Fischetti, V.A, Nelson, D.C, Whisstock, J.C.
登録日2012-05-17
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-ray crystal structure of the streptococcal specific phage lysin PlyC.
Proc.Natl.Acad.Sci.USA, 109, 2012
2R9Y
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BU of 2r9y by Molmil
Structure of antiplasmin
分子名称: Alpha-2-antiplasmin
著者Law, R.H.P, Sofian, T, Kan, W.T, Horvath, A.J, Hitchen, C.R, Langendorf, C.G, Buckle, A.M, Whisstock, J.C, Coughlin, P.B.
登録日2007-09-14
公開日2007-12-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献X-ray crystal structure of the fibrinolysis inhibitor {alpha}2-antiplasmin
Blood, 111, 2008
6EE5
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BU of 6ee5 by Molmil
Reactive centre loop dynamics and serpin specificity
分子名称: Conserpin-AATRCL
著者Marijanovic, E.M, Porebski, B.T, McGowan, S, Buckle, A.M.
登録日2018-08-13
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Reactive centre loop dynamics and serpin specificity.
Sci Rep, 9, 2019
2VH4
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BU of 2vh4 by Molmil
Structure of a loop C-sheet serpin polymer
分子名称: TENGPIN
著者Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M.
登録日2007-11-19
公開日2008-01-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
6NVB
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BU of 6nvb by Molmil
Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
分子名称: GLYCEROL, Kallikrein-4, SULFATE ION
著者Riley, B.T, Buckle, A.M, McGowan, S.
登録日2019-02-04
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.636 Å)
主引用文献Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.
Acta Crystallogr.,Sect.F, 75, 2019
6O21
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BU of 6o21 by Molmil
Crystal Structure of Human KLK4 in Complex With Cleaved SFTI-FCQR(Asn14)[1,14] Inhibitor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein 4 (Prostase, enamel matrix, ...
著者Ilyichova, O.V, Buckle, A.M.
登録日2019-02-22
公開日2019-03-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.
Biochemistry, 58, 2019
4U3H
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BU of 4u3h by Molmil
Crystal structure of FN3con
分子名称: FN3con
著者Porebski, B.T, McGowan, S, Buckle, A.M.
登録日2014-07-21
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.
Protein Eng.Des.Sel., 28, 2015
1YZW
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BU of 1yzw by Molmil
The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore
分子名称: DI(HYDROXYETHYL)ETHER, GFP-like non-fluorescent chromoprotein
著者Wilmann, P.G, Petersen, J, Pettikiriarachchi, A, Buckle, A.M, Devenish, R.J, Prescott, M, Rossjohn, J.
登録日2005-02-28
公開日2005-05-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The 2.1A Crystal Structure of the Far-red Fluorescent Protein HcRed: Inherent Conformational Flexibility of the Chromophore
J.Mol.Biol., 349, 2005
1SNG
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BU of 1sng by Molmil
Structure of a Thermophilic Serpin in the Native State
分子名称: COG4826: Serine protease inhibitor, SULFATE ION
著者Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C.
登録日2004-03-10
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.
J.Biol.Chem., 280, 2005
3VP6
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BU of 3vp6 by Molmil
Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation
分子名称: 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, Glutamate decarboxylase 1
著者Langendorf, C.G, Tuck, K.L, Key, T.L.G, Rosado, C.J, Wong, A.S.M, Fenalti, G, Buckle, A.M, Law, R.H.P, Whisstock, J.C.
登録日2012-02-27
公開日2013-01-16
最終更新日2013-08-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
Biosci.Rep., 33, 2013
1FY9
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BU of 1fy9 by Molmil
CRYSTAL STRUCTURE OF THE HEXA-SUBSTITUTED MUTANT OF THE MOLECULAR CHAPERONIN GROEL APICAL DOMAIN
分子名称: 60 KD CHAPERONIN, GLYCEROL
著者Wang, Q, Buckle, A.M, Fersht, A.R.
登録日2000-09-28
公開日2000-11-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Stabilization of GroEL minichaperones by core and surface mutations.
J.Mol.Biol., 298, 2000
1FYA
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BU of 1fya by Molmil
CRYSTAL STRUCTURE OF THE HEXA-SUBSTITUTED MUTANT OF THE MOLECULAR CHAPERONIN GROEL APICAL DOMAIN
分子名称: 60 KD CHAPERONIN, GLYCEROL
著者Wang, Q, Buckle, A.M, Fersht, A.R.
登録日2000-09-28
公開日2000-11-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Stabilization of GroEL minichaperones by core and surface mutations.
J.Mol.Biol., 298, 2000
5J7C
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BU of 5j7c by Molmil
A picomolar affinity FN3 domain in complex with hen egg-white lysozyme
分子名称: FNfn10-anti-lysozyme (DE0.4.1), Lysozyme C
著者Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M.
登録日2016-04-06
公開日2016-08-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.535 Å)
主引用文献Circumventing the stability-function trade-off in an engineered FN3 domain.
Protein Eng.Des.Sel., 2016
5J7K
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BU of 5j7k by Molmil
Loop grafting onto a highly stable FN3 scaffold
分子名称: FN3con-a-lys, ZINC ION
著者Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M.
登録日2016-04-06
公開日2016-08-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Circumventing the stability-function trade-off in an engineered FN3 domain.
Protein Eng.Des.Sel., 2016
5CDZ
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BU of 5cdz by Molmil
Crystal structure of conserpin in the latent state
分子名称: Conserpin in the latent state, GLYCEROL
著者Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M.
登録日2015-07-06
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
5CE0
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BU of 5ce0 by Molmil
Crystal structure of conserpin with Z-mutation
分子名称: Native conserpin with Z-variant (E342K)
著者Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M.
登録日2015-07-06
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
5CDX
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BU of 5cdx by Molmil
Crystal structure of conserpin
分子名称: Conserpin
著者Porebski, B.T, Borg, N.A, McGowan, S, Buckle, A.M.
登録日2015-07-06
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
1HJZ
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BU of 1hjz by Molmil
Crystal structure of AF1521 protein containing a macroH2A domain
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HYPOTHETICAL PROTEIN AF1521
著者Allen, M.D, Buckle, A.M, Cordell, S.C, Lowe, J, Bycroft, M.
登録日2003-03-05
公開日2003-07-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Af1521 a Protein from Archaeoglobus Fulgidus with Homology to the Non-Histone Domain of Macroh2A
J.Mol.Biol., 330, 2003
4K1E
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BU of 4k1e by Molmil
Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein-4, LITHIUM ION, ...
著者Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
登録日2013-04-04
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
4KGA
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BU of 4kga by Molmil
Crystal structure of kallikrein-related peptidase 4
分子名称: 1,2-ETHANEDIOL, Kallikrein-4, NICKEL (II) ION
著者Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
登録日2013-04-29
公開日2014-04-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
4K8Y
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BU of 4k8y by Molmil
Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower Trypsin Inhibitor (SFTI-1)
分子名称: Kallikrein-4, Trypsin inhibitor 1
著者Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
登録日2013-04-19
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
4KEL
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BU of 4kel by Molmil
Atomic resolution crystal structure of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR(N)
分子名称: Kallikrein-4, Trypsin inhibitor 1
著者Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
登録日2013-04-25
公開日2014-04-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.148 Å)
主引用文献KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.
Biochemistry, 58, 2019
3JZ4
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BU of 3jz4 by Molmil
Crystal structure of E. coli NADP dependent enzyme
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase [NADP+]
著者Langendorf, C.G, Key, T.L.G, Fenalti, G, Kan, W.T, Buckle, A.M, Caradoc-Davies, T, Tuck, K.L, Law, R.H.P, Whisstock, J.C.
登録日2009-09-22
公開日2010-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.
Plos One, 5, 2010
2H4R
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BU of 2h4r by Molmil
Crystal structure of wildtype MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
3EBG
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BU of 3ebg by Molmil
Structure of the M1 Alanylaminopeptidase from malaria
分子名称: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
著者McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C.
登録日2008-08-27
公開日2009-01-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase
Proc.Natl.Acad.Sci.USA, 106, 2009

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